Martine Extermann, MD Moffitt Cancer Center Tampa, FL, USA - - PowerPoint PPT Presentation

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Martine Extermann, MD Moffitt Cancer Center Tampa, FL, USA - - PowerPoint PPT Presentation

Feb 03, 2024 639 likes •783 views

Martine Extermann, MD Moffitt Cancer Center Tampa, FL, USA Education: 1 ! Increase public awareness to the worldwide cancer in the elderly epidemic and the need for a specific approach ! Political (Health ministries, international

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Martine Extermann, MD Moffitt Cancer Center Tampa, FL, USA

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Education: 1

! Increase public awareness to the

worldwide cancer in the elderly epidemic and the need for a specific approach

! Political (Health ministries, international

  • rganizations)

! Medical societies ! Advocacy networks, media, to develop a more

positive image of older cancer patients

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Education: 2

! Integrate geriatric oncology in the curricula

for medical and nursing education, both during studies and post-graduate education

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Education: 3

! Address the shortage of specialist

  • ncologists/geriatricians & allied health

staff in geriatric oncology

! Develop/support specific training programs ! Increase/develop funding to foster

academically oriented specialists able to address the populations not targeted by traditional oncology studies

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Clinical practice: 4

! Develop interdisciplinary geriatric oncology

clinics, especially in academic institutions and comprehensive cancer centers

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Clinical practice: 5

! Integrate geriatric evaluation (comorbidity

included) into oncology decision-making and guidelines.

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Clinical practice: 6

! Address issues of access to care,

including the needs of the caregiver

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Research: 7

! Develop, test and diffuse easy screening

tools to enable proper referral patterns to multidisciplinary clinics or integrated approaches between oncologists and geriatricians

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Research: 8

! Create a clear and operational definition of

vulnerability/frailty applicable in oncology

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Research: 9

! Increase the relevance of clinical trials for

  • lder patients:

! Require large phase III trials to oversample older

cancer patients in order reach a meaningful percentage of their cohorts, and to build their analyses to provide results specific and pertinent to this population.

! Extend phase II and III trials to patients with high

levels of comorbidity or functional impairment with stratified accruals or extension cohorts

! Design specific trials for older cancer patients

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Research: 10

! Promote multidisciplinary basic/

translational research on the interface of aging and cancer

Article: Extermann et al., J Geriatric Oncology, 2011 Pdf: www.siog.org

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Next steps

! SIOG is diffusing these priorities to health

authorities, professional associations, research group

! SIOG basic/translational workshop in

Manchester, UK www.siog.org

! Societies such as ASCO and ESMO have

developed educational material: use it!

! Use SIOG guidelines and NCCN elderly

guidelines

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PCC: today and tomorrow

NSCLC (histology) NSCLC

  • histology
  • EGFR
  • ERCC-1 & Co

Etc… Patient

  • ECOG PS
  • Age

Patient

  • ECOG PS
  • Comorbidity
  • CGA
  • Life expectancy
  • Biologic markers of

aging & functional reserve

Interaction