SLIDE 1
Liver transplant meeting 19th September 2017
Dr Tu Vinh Luong Royal Free Hospital
SLIDE 2 Royal Free Hospital - Case A
- Female 41 years
- Liver transplant in Feb 2017 for PBC.
- Stable at clinical follow-ups until July 2017
when a liver biopsy was performed for worsening graft function (ALT 210, AST 161, bilitubin 41).
SLIDE 3
Royal Free Hospital - Case A
SLIDE 4
Royal Free Hospital - Case A
SLIDE 5 Royal Free Hospital - Case A
DPAS HE
SLIDE 6
Royal Free Hospital - Case A
SLIDE 7
Royal Free Hospital - Case A
SLIDE 8 Royal Free Hospital - Case B
- Female 36 years
- Patient underwent transplant on 28.03.17 for PSC, receiving
a split graft.
- She developed graft dysfunction due to hepatic artery
thrombosis and required supraurgent re-transplantation on 06.04.17.
- The time zero liver biopsy at the 1st transplantation was
negative for C4d.
- The slides submitted are from the second transplantation
(split graft) and post transplant liver biopsy performed on day 5 after the second transplant.
- Split graft/second explant - slides 381810 and 381811.
- Day 5 - slides 381812 and 381813.
SLIDE 9
Split graft/second explant slide 381810
SLIDE 10
Split graft/second explant slide 381810
SLIDE 11
Split graft/second explant slide 381810
SLIDE 12
Split graft/second explant slide 381810
SLIDE 13
Split graft/second explant slide 381810
SLIDE 14
Split graft/second explant slide 381810
SLIDE 15
Split graft/second explant slide 381811 – C4d
SLIDE 16
Split graft/second explant slide 381811 – C4d
SLIDE 17
Split graft/second explant slide 381811 – C4d
SLIDE 18 Further clinical information
- Positivity for donor specific antibodies
- Treatment with cycles of plasma exchange
SLIDE 19
Day 5 - slides 381812
SLIDE 20
Day 5 - slides 381812
SLIDE 21
Day 5 - slides 381812
SLIDE 22
Day 5 - slides 381813 – C4d
SLIDE 23
Day 5 - slides 381813 – C4d
SLIDE 24
Day 5 - slides 381813 – C4d
