Lessons learned from research that led to debate on dual use - - PowerPoint PPT Presentation

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Lessons learned from research that led to debate on dual use - - PowerPoint PPT Presentation

Jun 21, 2023 147 likes •309 views

Lessons learned from research that led to debate on dual use Christianne Bruschke Arnold Dwarkasing Rik Bleijs Spanish Flu 2 3 Infectious Disease Research Loss-of-function Take virulent/transmissible/resistant virus and test how it can

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Lessons learned from research that led to debate on dual use

Christianne Bruschke Arnold Dwarkasing Rik Bleijs

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Spanish Flu

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Infectious Disease Research

Loss-of-function

  • Take virulent/transmissible/resistant virus and test how it can

loose these functions Gain-of function

  • Take non-virulent/non-transmissible/sensitive virus and test how it

gain these functions Reduction of biological threats Induction of biological threats/ Dual Use

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Biosafety: keep bad bugs away from people Biosecurity: keep bad people away from bugs

Murray L. Cohen, NSABB National Science Advisory Board for Biosecurity

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Biosecurity pillars

Personnel Security Physical Security Material Accoun- tability Transport Security Information Security Awareness Management & Organisation Response

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Biosecurity policy in The Netherlands

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Aims of the Government:

  • Reducing the risk of misuse of biological agents
  • Safe and effective action in case of emergencies (response)

Targets of the Government:

  • Integrate Biosafety and Biosecurity -> develop biorisk policy
  • Further strengthen the implementation of international conventions
  • Link with existing biosafety management
  • Outreach and awareness raising among biosecurity professionals

and scientists

Bottom-up approach

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The Netherlands Biosecurity Office

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Government Professionals

  • Advice on biosecurity policy development
  • Integrate biosafety and biosecurity
  • Link biosafety management
  • Biorisk professional
  • Outreach, bottom-up, awareness
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Biosecurity Self-scan toolkit

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Biosecurity Network

  • Indication of the current biosecurity level
  • Identify potential gaps
  • Legal basis and a set of good practices

http://www.biosecuritytoolkit.com

The Netherlands Biosecurity Office | 28 April 2017 www.bureaubiosecurity.nl

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Biosecurity Vulnerability Scan

http://www.biosecurityvulnerabilityscan.nl

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Dual-use considerations in the research chain: from grant application to publication

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Idea Funding Research Manuscript Publication time

Be aware of potential dual-use issues throughout the whole research chain

Many years

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Current legislation in the Netherlands

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Biosecurity/Dual Use:

  • Council regulation EC 428/2009

setting up a Community regime for the control of exports, transfer, brokering and transit of dual-use items

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Further developments

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  • Interministerial working group working on:
  • Accompanying legislation
  • Classification of pathogens
  • Notification obligation
  • ….
  • Biorisk Officer
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Conclusion

  • Substantial threat of biological agents.
  • Awareness raising through bottom up approach
  • Government responsible for accompanying legislation

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Acknowledgements

  • Ron Fouchier, Erasmus Medical Centre
  • Niels Berg, Ministry of Economic Affairs
  • Maaike van den Biggelaar, Ministry of Health Welfare and Sports
  • Gerlof Kruithof, Kees Jan Steenhoek, Ministry of Foreign Affairs

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