Legalization of Marijuana Mental Health, Substance Use Disorder - - PowerPoint PPT Presentation
Legalization of Marijuana Mental Health, Substance Use Disorder Effects, Consequences Sheila Specker, MD Addiction Psychiatrist University of Minnesota MPS President Minnesota Psychiatric Society Improving Minnesota's mental health care
Sheila Specker, MD Addiction Psychiatrist University of Minnesota MPS President
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care. 1
2
NIDA, MNSAM, ASAM, MPS, SAM
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.
VTA/SN nucleus accumbens frontal cortex
150 125 100 0 20 40 60 80
MARIJUANA
% of Basal Release
100 200 300 400 500 600 700 800 900 1000 1100 1 2 3 4 5 hr
AMPHETAMINE
% of Basal Release Tanda, et al, Science 1997.
Slide courtesy of Ken Winters, Maureen Boyle, PhD
4
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.
32 15 9 17 11 8 5 23 5 10 15 20 25 30 35 Percent
Source: Anthony JC et al., 1994
* *
If youth onset
6
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.
Campbell et al., 2018
7
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.
8
35
SAMHSA,2019, Volkow, et al., 2014
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.
(Dunedin Longitudinal Study)
9
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.
▪ 901 patients with first episode psychosis across 11 clinic sites in Europe ▪ Compared 1237 population controls from those same sites ▪ Cannabis use was associated with increased
never users
▪ Daily use of low potency cannabis = adjusted
▪ Daily use of high potency cannabis = adjusted odds ratio, 4.8 (95% CI 2.5 – 6.3) Source: Lancet Psychiatry, 2019
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.
Miller’s Review of the Cannabis and Mental Health Connection
Miller, C. L. (2018). The impact of marijuana on mental health. In K. Sabet & K.C. Winters, Contemporary health issues on marijuana. NY: Oxford Press.
Key: ++ = several studies; +a few studies Yellow box = risk greater when cannabis use onset during youth.
12
Minnesota Psychiatric Society
Improving Minnesota's mental health care through education, advocacy and sound psychiatric practice. Our vision is physician leadership creating the nation's highest quality, affordable and accessible system of mental health care.