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Endogenous Subgroup Analysis Using ASPES Laura Peck, Eleanor Harvill & Shawn Moulton, Abt Associates Society for Research on Educational Effectiveness Washington, DC | March 2017 Acknowledgment of Funding ASPES method development is


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SLIDE 1

Endogenous Subgroup Analysis Using ASPES

Laura Peck, Eleanor Harvill & Shawn Moulton, Abt Associates Society for Research on Educational Effectiveness Washington, DC | March 2017

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SLIDE 2

Abt Associates | pg 1

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • ASPES method development is funded by an

Institute of Education Sciences Early Career Methods Grant.

  • The research reported here was supported by the

Institute of Education Sciences, U.S. Department of Education, through Grant R305D150016.

  • The opinions expressed are those of the authors and

do not represent views of the Institute or the U.S. Department of Education.

Acknowledgment of Funding

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SLIDE 3

Endogenous Subgroup Analysis Using ASPES

Part 1: Introduction Laura Peck Society for Research on Educational Effectiveness Washington, DC | March 2017

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SLIDE 4

Abt Associates | pg 3

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Introductions: to each other, to the course material
  • What this workshop is about: Mediators and mediation

analysis, with experimental data

  • Overview of five methods: Structural Equation Modeling

(SEM), Instrumental Variables (IV), Principal Stratification, Propensity Score Matching (PSM), Analysis of Symmetrically- Predicted Endogenous Subgroups (ASPES)

  • Comparison of methods: research questions, estimation

process, assumptions, interpretation

  • Detailed instruction in one method: ASPES
  • Illustrative example

Agenda

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SLIDE 5

Abt Associates | pg 4

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Introductions: to each other, to the course material
  • What this workshop is about: Mediators and mediation

analysis, with experimental data

  • Overview of five methods: Structural Equation Modeling

(SEM), Instrumental Variables (IV), Principal Stratification, Propensity Score Matching (PSM), Analysis of Symmetrically- Predicted Endogenous Subgroups (ASPES)

  • Comparison of methods: research questions, estimation

process, assumptions, interpretation

  • Detailed instruction in one method: ASPES
  • Illustrative example

Agenda

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SLIDE 6

Abt Associates | pg 5

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Introductions: to each other, to the course material
  • What this workshop is about: Mediators and mediation

analysis, with experimental data

  • Overview of five methods: Structural Equation Modeling

(SEM), Instrumental Variables (IV), Principal Stratification, Propensity Score Matching (PSM), Analysis of Symmetrically- Predicted Endogenous Subgroups (ASPES)

  • Comparison of methods: research questions, estimation

process, assumptions, interpretation

  • Detailed instruction in one method: ASPES
  • Illustrative example

Agenda

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SLIDE 7

Abt Associates | pg 6

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Introductions: to each other, to the course material
  • What this workshop is about: Mediators and mediation

analysis, with experimental data

  • Overview of five methods: Structural Equation Modeling

(SEM), Instrumental Variables (IV), Principal Stratification, Propensity Score Matching (PSM), Analysis of Symmetrically- Predicted Endogenous Subgroups (ASPES)

  • Comparison of methods: research questions, estimation

process, assumptions, interpretation

  • Detailed instruction in one method: ASPES
  • Illustrative example

Agenda

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SLIDE 8

Abt Associates | pg 7

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • To instructors:

– Eleanor Harvill – Shawn Moulton – Laura Peck

  • To each other:

– Name, affiliation

Introductions

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SLIDE 9

Abt Associates | pg 8

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Mediator = intermediate variable:

– Program-related: element of program, such as “peer support groups” – Person-related: milestone achieved, such as “earned HS degree/GED”

What this workshop is about

Treatment (T) Mediator (M) Outcome (Y)

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SLIDE 10

Abt Associates | pg 9

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Mediator = intermediate variable:

– Program-related: element of program, such as “peer support groups” – Person-related: milestone achieved, such as “earned HS degree/GED”

  • Indirect effect (of T on Y, given M) = a*b
  • Direct effect (of T on Y) = c
  • Proportion of effect that is indirect

What this workshop is about

Treatment (T) Mediator (M) Outcome (Y) a b c

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SLIDE 11

Abt Associates | pg 10

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Mediator = intermediate variable:

– Program-related: element of program, such as “peer support groups” – Person-related: milestone achieved, such as “earned HS degree/GED”

  • Indirect effect (of T on Y, given M) = a*b
  • Direct effect (of T on Y) = c
  • Proportion of effect that is indirect

What this workshop is about

Treatment (T) Mediator (M) Outcome (Y) a b c Two kinds of Qs to answer

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SLIDE 12

Abt Associates | pg 11

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Structural Equation Modeling
  • Instrumental Variables
  • Principal Stratification
  • Propensity Score Matching
  • Analysis of Symmetrically-predicted Endogenous Subgroups

What this workshop is about

Treatment (T) Mediator (M) Outcome (Y) a b c

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SLIDE 13

Abt Associates | pg 12

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Structural Equation Modeling
  • Instrumental Variables
  • Principal Stratification
  • Propensity Score Matching
  • Analysis of Symmetrically-predicted Endogenous Subgroups

What this workshop is about

Treatment (T) Mediator (M) Outcome (Y) a b c

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SLIDE 14

Abt Associates | pg 13

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Structural Equation Modeling
  • Instrumental Variables
  • Principal Stratification
  • Propensity Score Matching
  • Analysis of Symmetrically-predicted Endogenous Subgroups

What this workshop is about

Treatment (T) Mediator (M) Outcome (Y) a b c

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SLIDE 15

Abt Associates | pg 14

SREE 2017 | Endogenous Subgroup Analysis Workshop

Endogenous Subgroups Conceptually

When exposed to treatment…

  • used program feature Z (or not)
  • experienced high dosage of intervention
  • followed treatment path W-X-Y
  • behaved a particular way

If exposed to treatment, would have…

  • used program feature Z (or not)
  • experienced high dosage of intervention
  • followed treatment path W-X-Y
  • behaved a particular way

Treatment Group Control Group

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SLIDE 16

Abt Associates | pg 15

SREE 2017 | Endogenous Subgroup Analysis Workshop

Likewise…

In the absence of the treatment…

  • dropped out of school (or not)
  • experienced long-term unemployment
  • had less favorable LM outcomes
  • behaved a particular way

If not exposed to treatment, would have…

  • dropped out of school (or not)
  • experienced long-term unemployment
  • had less favorable LM outcomes
  • behaved a particular way

Control Group Treatment Group

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Abt Associates | pg 16

SREE 2017 | Endogenous Subgroup Analysis Workshop

Average Treatment Effect v…

  • … the “Story is in the Subgroups”

– Exogenous

  • Uni-dimensional (e.g., women, low-education, prior arrest)
  • Multi-dimensional (e.g., disadvantaged, “at risk”)

– Endogenous

  • Uni-dimensional (e.g., took up offer, experienced intervention

delivered with “fidelity”)

  • Multi-dimensional (e.g., experienced some dosage,

participated in this package of services)

  • Mediation

– as programmatic factor – as personal characteristics

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Abt Associates | pg 17

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Baron & Kenny (1986)
  • Addresses both kinds of Qs (direct, indirect effects)
  • Notation:

– Binary treatment: T=1 (Treatment), T=0 (Control) – M=Mediator, Y=Outcome, X=Baseline characteristics

  • Direct and indirect effects are estimated using:

𝑁 = 𝛽 + 𝑏𝑈 + 𝒀𝜌 + 𝑓1 𝑍 = 𝛾 + 𝑐𝑁 + 𝑑𝑈 + 𝒀𝜒 + 𝑓2

  • Estimated indirect effect: 𝜀

= 𝑏 ∗ 𝑐

  • Estimated direct effect: 𝛿

= 𝑑

Structural Equation Modeling Basics

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Abt Associates | pg 18

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Stable Unit Treatment Value Assumption (SUTVA)
  • Treatment assignment is random
  • Linearity
  • No interaction between 𝑁 and 𝑈
  • Ignorability of observed mediator status: Conditional
  • n 𝒀, 𝑁 is not correlated with the error, 𝑓2

SEM Assumptions

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Abt Associates | pg 19

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Stable Unit Treatment Value Assumption (SUTVA)
  • Treatment assignment is random
  • Linearity
  • No interaction between 𝑁 and 𝑈
  • Ignorability of observed mediator status: Conditional
  • n 𝒀, 𝑁 is not correlated with the error, 𝑓2

SEM Assumptions

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Abt Associates | pg 20

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Angrist, Imbens, and Rubin (1996)
  • Addresses only the indirect effect question:

– What is the effect of take up?

  • Use exogenous variation in mediator created by

treatment to estimate effect of mediator on outcome (the indirect effect)

Instrumental Variables Basics

(w/experiment)

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Abt Associates | pg 21

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Angrist, Imbens, and Rubin (1996)
  • Addresses only the indirect effect question:

– What is the effect of take up?

  • Use exogenous variation in mediator created by

treatment to estimate effect of mediator on outcome

Instrumental Variables Basics

(w/experiment)

Treatment Group

no shows took up

  • ffer

Control Group

took up

  • ffer
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SLIDE 23

Abt Associates | pg 22

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Using 2SLS, fit the first stage model:

𝑁 = 𝛽 + 𝑏𝑈 + 𝒀𝜌 + 𝑓1

  • Predict 𝑁

(which is free of unobserved W and measurement error)

  • Use the predicted mediator, 𝑁

, in the second stage: 𝑍 = 𝛾 + 𝑐𝑁 + 𝒀𝜒 + 𝑓2

Instrumental Variables Basics (cont.)

Treatment (T) Mediator (M) Outcome (Y) a b

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Abt Associates | pg 23

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • SUTVA
  • Treatment assignment is random
  • Linearity
  • Treatment effect on the mediator is non-zero

– Also known as instrument effectiveness

  • No direct effect (i.e., M is the only mediator)

– Also known as the “exclusion restriction”

IV Assumptions

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Abt Associates | pg 24

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • SUTVA
  • Treatment assignment is random
  • Linearity
  • Treatment effect on the mediator is non-zero

– Also known as instrument effectiveness

  • No direct effect (i.e., M is the only mediator)

– Also known as the “exclusion restriction”

IV Assumptions

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Abt Associates | pg 25

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • A generalized case of IV (Frangakis & Rubin, 2002)

and ASPES (Bein, 2013)

  • Provides a framework for organizing subgroup

impacts

  • Addresses (indirectly) both kinds of Qs (direct,

indirect effects)

  • Partition sample into strata based on potential values
  • f mediator and use strata-specific effects to make

inferences about a, b, and c

  • In practice, it can use varied analytic procedures

Principal Stratification Basics

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Abt Associates | pg 26

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Binary mediator; M=high or M=low
  • 𝑁𝑈: Potential mediator status under treatment
  • 𝑁𝐷: Potential mediator status under control
  • Sample is in one of four groups based on 𝑁𝑈 & 𝑁𝐷:

– Always-High (A): 𝑁𝑈=high and 𝑁𝐷=high – Treatment only-High (TO): 𝑁𝑈=high and 𝑁𝐷=low – Control only-High (CO): 𝑁𝑈=low and 𝑁𝐷=high – Never-High (N): 𝑁𝑈=low and 𝑁𝐷=low

Principal Stratification Notation

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Abt Associates | pg 27

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Binary mediator; M=high or M=low
  • 𝑁𝑈: Potential mediator status under treatment
  • 𝑁𝐷: Potential mediator status under control
  • Sample is in one of four groups based on 𝑁𝑈 & 𝑁𝐷:

– Always-High (A): 𝑁𝑈=high and 𝑁𝐷=high (always takers) – Treatment only-High (TO): 𝑁𝑈=high and 𝑁𝐷=low (compliers) – Control only-High (CO): 𝑁𝑈=low and 𝑁𝐷=high (defiers) – Never-High (N): 𝑁𝑈=low and 𝑁𝐷=low (never takers)

Principal Stratification Notation

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Abt Associates | pg 28

SREE 2017 | Endogenous Subgroup Analysis Workshop

Principal Stratification (cont.)

Principal Strata

  • By definition, there are no

indirect effects on A and N

  • Effects on TO and CO reflect

direct and indirect effects

  • Estimation challenge: Stratum

membership is not observable in both experimental states

Mediation Analysis and PS

Treatment C

  • n

t r

  • l

M=High M=Low M=High

A CO

M=Low

TO N

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Abt Associates | pg 29

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • SUTVA
  • Observed Mediator Status under T or C = Potential

Mediator Status under that condition.

  • Treatment assignment is random.
  • Principal Ignorability: Principal stratum membership

is fully explained by pretreatment attributes 𝒀

PS Assumptions

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Abt Associates | pg 30

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • SUTVA
  • Observed Mediator Status under T or C = Potential

Mediator Status under that condition

  • Treatment assignment is random
  • Principal Ignorability: Principal stratum membership

is fully explained by pretreatment attributes 𝒀

PS Assumptions

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Abt Associates | pg 31

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Page (2012) uses a Bayesian approach
  • Stuart and Jo (2012) use propensity score matching
  • Unlu et al. (2013) use double propensity scoring

PS-based Estimation

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Abt Associates | pg 32

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • The Analysis of Symmetrically-Predicted

Endogenous Subgroups (ASPES) method provides a framework for creating experimentally valid subgroups defined by some post random assignment event or path (Peck, 2003, 2013)

  • Requires an experimentally designed evaluation and

baseline data

Analysis of Symmetrically Predicted Endogenous Subgroups

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Abt Associates | pg 33

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Discrete endogenous subgroups

– Potential effects on “no-shows” – Treatment dosage or quality (low, medium, high) – Treatment components, pathways – Control group fall-back experience

  • Continuous endogenous indicators

– Treatment dosage or quality (along a continuum) – Continuous mediating factors – Control group fall-back experience

Kinds of Questions

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Abt Associates | pg 34

SREE 2017 | Endogenous Subgroup Analysis Workshop

Classes of Endogenous Groups

  • (1) Potential effects on “no-shows”
  • Examples

– NYCAP: non-takers still made changes to try and take advantage of new policy structure – MTO: those who did not lease up still got counseling services and tried

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Abt Associates | pg 35

SREE 2017 | Endogenous Subgroup Analysis Workshop

Classes of Endogenous Groups

  • (2) Treatment dosage or quality
  • Examples

– BSF:

  • what impact does full participation have? (discrete)
  • what impact does the number of hours have? (continuous)

– HSIS: what generates greater impacts…

  • two years, rather than one?
  • being in a better quality center? (discrete or continuous)
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Abt Associates | pg 36

SREE 2017 | Endogenous Subgroup Analysis Workshop

Classes of Endogenous Groups

  • (3) Multi-faceted treatment components/pathways
  • Examples

– NEWWS: what impact does [sanction] have? – HPOG: what is it about intervention that drives impacts?

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Abt Associates | pg 37

SREE 2017 | Endogenous Subgroup Analysis Workshop

Classes of Endogenous Groups

  • (4) Subsets of the control group conditions that make

particular fall-back choices when denied access to the intervention

  • Examples

– Career Academies: those who dropped out of school – HSIS: those who stay at home with parent(s) – JTPA: those with better/worse labor market outcomes

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Abt Associates | pg 38

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • See Comparison of Methods for Mediation Analysis

Handout

  • Methods differ in terms of:

– Research Question Addressed – Estimation Process – Key Assumptions – Interpretation – Data Requirements

Comparison of Methods for Mediation Analysis

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SLIDE 40

Abt Associates | pg 39

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Up next: Ellie on ASPES Instruction

Break 1

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SLIDE 41

Endogenous Subgroup Analysis Using ASPES

Part 2: ASPES Instruction Eleanor Harvill Society for Research on Educational Effectiveness Washington, DC | March 2017

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Abt Associates | pg 41

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • In 2004, the U.S. Department of Education’s Institute
  • f Education Sciences contracted with Mathematica

Policy Research to conduct the Comprehensive Teacher Induction (CTI) Study.

  • CTI Study Design: 418 elementary schools in 17

urban districts were assigned by lottery to either:

– a treatment group whose beginning teachers were offered comprehensive teacher induction or – a control group whose beginning teachers received the district’s “business as usual” induction services

  • See Impacts of Comprehensive Teacher Induction,

Glazerman et al. (2010)

Comprehensive Teacher Induction (CTI) Study

  • Abt Associates | pg. 41
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Abt Associates | pg 42

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • In this section, we will introduce the mechanics of the

method using the CTI study as a concrete example

  • We are interested in how the intensity of mentorship

affects the impact of CTI

  • We operationalize the intensity of mentorship in two

ways:

– Number of classroom observations by a mentor teacher (continuous measure) – Indicator for number of observations at or above the median (binary measure)

  • This section presents methods for analyzing both

mediators

  • The following section walks through the results of

such an analysis

Illustrating ASPES with CTI Study Details

  • Abt Associates | pg. 42
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SLIDE 44

Abt Associates | pg 43

SREE 2017 | Endogenous Subgroup Analysis Workshop

ASPES Conceptually

When exposed to treatment…

  • used program feature Z (or not)
  • experienced high dosage of intervention
  • followed treatment path W-X-Y
  • behaved a particular way

If exposed to treatment, would have…

  • used program feature Z (or not)
  • experienced high dosage of intervention
  • followed treatment path W-X-Y
  • behaved a particular way

Treatment Group Control Group

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SLIDE 45

Abt Associates | pg 44

SREE 2017 | Endogenous Subgroup Analysis Workshop

A Primer on How To

Continuous Mediator

  • Step 1: Predict values of the

mediator

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting

Binary Mediator

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SLIDE 46

Abt Associates | pg 45

SREE 2017 | Endogenous Subgroup Analysis Workshop

A Primer on How To

Continuous Mediator

  • Step 1: Predict values of the

mediator

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: estimate the relationship

between the predicted continuous mediator and impact

Binary Mediator

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SLIDE 47

Abt Associates | pg 46

SREE 2017 | Endogenous Subgroup Analysis Workshop

A Primer on How To

Continuous Mediator

  • Step 1: Predict values of the

mediator

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: estimate the relationship

between the predicted continuous mediator and impact

Binary Mediator

  • Step 1: Predict values of the

mediator and construct predicted subgroups

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
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SLIDE 48

Abt Associates | pg 47

SREE 2017 | Endogenous Subgroup Analysis Workshop

A Primer on How To

Continuous Mediator

  • Step 1: Predict values of the

mediator

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: estimate the relationship

between the predicted continuous mediator and impact

Binary Mediator

  • Step 1: Predict values of the

mediator and construct predicted subgroups

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: Estimate impacts on

predicted subgroups

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SLIDE 49

Abt Associates | pg 48

SREE 2017 | Endogenous Subgroup Analysis Workshop

A Primer on How To

Continuous Mediator

  • Step 1: Predict values of the

mediator

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: estimate the relationship

between the predicted continuous mediator and impact

Binary Mediator

  • Step 1: Predict values of the

mediator and construct predicted subgroups

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: Estimate impacts on

predicted subgroups

  • Step 3: Convert estimated impacts

for predicted subgroups to represent actual subgroups

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Abt Associates | pg 49

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Predict values of the mediator by:

– Estimating a model that relates mentorship to baseline characteristics in the treatment group – Using these estimates to predict mentorship for both the treatment and control group

  • Key points:

– Predicted subgroups are defined based on exogenous baseline characteristics – In expectation, random assignment insures that the predicted values of the mediator is independent of treatment status

Step 1: Predict Mentorship

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Abt Associates | pg 50

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • What is overfitting?

– If one uses the entire treatment group to estimate mentorship (as offered by CTI), the model will do a better job of predicting mentorship in treatment group than it does in the control group.

  • This introduces an imbalance into the analysis of

predicted subgroups, which biases estimates.

  • How to avoid overfitting?

– Use a cross-validation approach so that all prediction is out-

  • f-sample

– Cross-validation allows you to do out-of-sample prediction for all sample members with no loss of sample

Step 1: Predict values of the mediator (Issue: Overfitting)

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Abt Associates | pg 51

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Split Sample Approach

– Divide your treatment group in two: a prediction sample and an analysis sample – Estimate the prediction model on the treatment group prediction sample – Predict values of the mediator for the treatment group analysis sample and the control group

Step 1: Predict values of the mediator (Issue: Overfitting)

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SLIDE 53

Abt Associates | pg 52

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Split Sample Approach

– Divide your treatment group in two: a prediction sample and an analysis sample – Estimate the prediction model on the treatment group prediction sample – Predict values of the mediator for the treatment group analysis sample and the control group

  • Downside: loss of sample for analysis

Step 1: Predict values of the mediator (Issue: Overfitting)

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SLIDE 54

Abt Associates | pg 53

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Split Sample Approach

– Divide your treatment group in two: a prediction sample and an analysis sample – Estimate the prediction model on the treatment group prediction sample – Predict values of the mediator for the treatment group analysis sample and the control group

  • Downside: loss of sample for analysis
  • Solution: What if you did another out of sample

prediction?

Step 1: Predict values of the mediator (Issue: Overfitting)

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SLIDE 55

Abt Associates | pg 54

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Split Sample Approach

– Divide your treatment group in two: a prediction sample and an analysis sample – Estimate the prediction model on the treatment group prediction sample – Predict values of the mediator for the treatment group analysis sample and the control group

  • Downside: loss of sample for analysis
  • Solution: What if you did another out of sample

prediction?

– Estimate prediction model on treatment group analysis sample – Predict mediator values for treatment group prediction sample

Step 1: Predict values of the mediator (Issue: Overfitting)

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SLIDE 56

Abt Associates | pg 55

SREE 2017 | Endogenous Subgroup Analysis Workshop

Steps in cross-validation: 1. Randomly partition your sample (both T and C) into 10 groups

  • f equal size

Step 1: Predict values of the mediator (Solution: Cross-Validation)

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SLIDE 57

Abt Associates | pg 56

SREE 2017 | Endogenous Subgroup Analysis Workshop

Steps in cross-validation: 1. Randomly partition your sample (both T and C) into 10 groups

  • f equal size

2. Obtain predictions for group 1 by:

Step 1: Predict values of the mediator (Solution: Cross-Validation)

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SLIDE 58

Abt Associates | pg 57

SREE 2017 | Endogenous Subgroup Analysis Workshop

Steps in cross-validation: 1. Randomly partition your sample (both T and C) into 10 groups

  • f equal size

2. Obtain predictions for group 1 by:

  • Estimating the prediction model on treatment individuals in groups

2-10

Step 1: Predict values of the mediator (Solution: Cross-Validation)

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SLIDE 59

Abt Associates | pg 58

SREE 2017 | Endogenous Subgroup Analysis Workshop

Steps in cross-validation: 1. Randomly partition your sample (both T and C) into 10 groups

  • f equal size

2. Obtain predictions for group 1 by:

  • Estimating the prediction model on treatment individuals in groups

2-10

  • Predicting dosage for both treatment and control individuals in

group 1

Step 1: Predict values of the mediator (Solution: Cross-Validation)

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SLIDE 60

Abt Associates | pg 59

SREE 2017 | Endogenous Subgroup Analysis Workshop

Steps in cross-validation: 1. Randomly partition your sample (both T and C) into 10 groups

  • f equal size

2. Obtain predictions for group 1 by:

  • Estimating the prediction model on treatment individuals in

groups 2-10

  • Predicting dosage for both treatment and control individuals

in group 1 3. Obtain predictions for group 2 by:

  • Estimating the prediction model on treatment individuals in

groups 1 and 3-10

  • Predicting dosage for both treatment and control individuals

in group 2 4. …

Step 1: Predict values of the mediator (Solution: Cross-Validation)

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SLIDE 61

Abt Associates | pg 60

SREE 2017 | Endogenous Subgroup Analysis Workshop

Step 1: Predict values of the mediator (Solution: Cross-Validation)

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SLIDE 62

Abt Associates | pg 61

SREE 2017 | Endogenous Subgroup Analysis Workshop

Step 1: Predict values of the mediator

Continuous Mediator

  • Example: Number of classroom
  • bservations by a mentor teacher
  • Use a cross validation approach to

construct predicted number of classroom observations by a mentor teacher

Binary Mediator

  • Example: Indicator for number of
  • bservations at or above the

median

  • Use a cross validation approach to

construct predicted number of classroom observations by a mentor teacher

  • Create an indicator for predicted

number of observations at or above the median

  • (Alternatively, you could discretize

first)

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Continuous ASPES: Stage 2: Impact Model

  • Estimate the Relationship between the Predicted Mediator

and Effect Size: Y= β0 + β1 𝑁 𝑄+ β2T + β3T 𝑁 𝑄+𝜁2

– 𝑍 is the outcome being examined; – 𝑁 𝑄 is the predicted value of the mediator generated from Stage 1; – 𝑈 indicates whether the member was assigned to the treatment or control group; and – 𝜁2 is an error term that captures all other factors that influence the outcome.

  • The impact of being assigned to the treatment group is

given by the following equation: 𝜖𝑍

𝜖𝑈 = 𝛾2 + 𝛾3𝑁

𝑄

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  • We require that:

– The baseline covariates that predict 𝑁𝑄 have no direct or indirect effect on the impact Δ apart from their indirect effect

  • n Δ through 𝑁𝐵
  • If this assumption holds, the coefficient of the

predicted mediator reflects the increase in impact associated with a unit increase in the actual mediator

Continuous ASPES: Key Assumption

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Continuous ASPES: Key Assumption

Δ T 𝑁1𝐵 𝑁1𝑄 X This assumption may be violated if the baseline characteristics X used to predict the mediator 𝑁1𝑄 influence the impact Δ through channels other than the actual number of observations 𝑁1𝐵 Assumes no direct or indirect effect

  • f X on Δ

𝑁2𝐵

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SLIDE 66

Abt Associates | pg 65

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • To interpret the coefficient 𝛾3 as the causal increase

in student achievement expected from each additional teacher observation, we require:

– A given mediator-value-defined subpopulation would experience the same impact as an alternative mediator- value-defined subpopulation if they were coerced to receive the corresponding alternative value of the mediator. – This assumption may be violated if study members attributes (e.g., motivation, ability, etc.) vary significantly across subpopulations since these differences in attributes may drive differential subpopulation effects.

Assumption for interpreting 𝛾3 as the causal increase in student achievement

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A Primer on How To

Continuous Mediator

  • Step 1: Predict values of the

mediator

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: estimate the relationship

between the predicted continuous mediator and impact

Binary Mediator

  • Step 1: Predict values of the

mediator and construct predicted subgroups

– Use baseline (exogenous) characteristics to predict the value

  • f the mediator

– Employ an approach to avoid

  • verfitting
  • Step 2: Estimate impacts on

predicted subgroups

  • Step 3: Convert estimated impacts

for predicted subgroups to represent actual subgroups

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SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Consider two groups, A & B:

– 𝐽𝐵 = 𝑍 𝑈𝐵 − 𝑍

𝐷𝐵 and 𝐽𝐶 = 𝑍

𝑈𝐶 − 𝑍

𝐷𝐶

  • Or, estimate:

– yi = α + δTi + βXi + ei – y is the outcome; – α is the intercept (interpreted as the control mean outcome); – T is the treatment indicator (treatment = 1; control = 0); – δ is the impact of the treatment (on subgroup of interest); – X is a vector of baseline characteristics; – β are the coefficients on the baseline characteristics; – e is the residual; and – the subscript i indexes individuals.

Binary ASPES: Step 2: Estimate Impacts

  • n Predicted Subgroups
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SREE 2017 | Endogenous Subgroup Analysis Workshop

  • In the two group case:

– 𝐽𝐵 = 𝑥𝐵𝐵𝐵 + (1 − 𝑥𝐵)𝐶𝐵 – 𝐽𝐶 = 𝑥𝐶𝐶𝐶 + (1 − 𝑥𝐶)𝐵𝐶

where

– I is the impact on predicted Subgroup members; – A is the impact on actual Subgroup A; – B is the impact on actual Subgroup B; – w is the proportion of predicted Subgroup members who are actually in the Subgroup; and – the subscripts A & B denote Subgroup membership.

Binary ASPES: Step 3: Convert from Predicted to Actual

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SLIDE 70

Abt Associates | pg 69

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • In the two group case:

– 𝐽𝐵 = 𝑥𝐵𝐵𝐵 + (1 − 𝑥𝐵)𝐶𝐵 – 𝐽𝐶 = 𝑥𝐶𝐶𝐶 + (1 − 𝑥𝐶)𝐵𝐶

where

– I is the impact on predicted Subgroup members; – A is the impact on actual Subgroup A; – B is the impact on actual Subgroup B; – w is the proportion of predicted Subgroup members who are actually in the Subgroup; and – the subscripts A & B denote Subgroup membership.

Binary ASPES: Step 3: Convert from Predicted to Actual

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SLIDE 71

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SREE 2017 | Endogenous Subgroup Analysis Workshop

  • In the two group case:

– 𝐽𝐵 = 𝑥𝐵𝐵𝐵 + (1 − 𝑥𝐵)𝐶𝐵 – 𝐽𝐶 = 𝑥𝐶𝐶𝐶 + (1 − 𝑥𝐶)𝐵𝐶

where

– I is the impact on predicted Subgroup members; – A is the impact on actual Subgroup A; – B is the impact on actual Subgroup B; – w is the proportion of predicted Subgroup members who are actually in the Subgroup; and – the subscripts A & B denote Subgroup membership.

Binary ASPES: Step 3: Convert from Predicted to Actual

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SLIDE 72

Abt Associates | pg 71

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  • In the two group case:

– 𝐽𝐵 = 𝑥𝐵𝐵𝐵 + (1 − 𝑥𝐵)𝐶𝐵 – 𝐽𝐶 = 𝑥𝐶𝐶𝐶 + (1 − 𝑥𝐶)𝐵𝐶

where

– I is the impact on predicted Subgroup members; – A is the impact on actual Subgroup A; – B is the impact on actual Subgroup B; – w is the proportion of predicted Subgroup members who are actually in the Subgroup; and – the subscripts A & B denote Subgroup membership.

Binary ASPES: Step 3: Convert from Predicted to Actual

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SLIDE 73

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SREE 2017 | Endogenous Subgroup Analysis Workshop

  • In the two group case:

– 𝐽𝐵 = 𝑥𝐵𝐵𝐵 + (1 − 𝑥𝐵)𝐶𝐵 – 𝐽𝐶 = 𝑥𝐶𝐶𝐶 + (1 − 𝑥𝐶)𝐵𝐶

where

– I is the impact on predicted Subgroup members; – A is the impact on actual Subgroup A; – B is the impact on actual Subgroup B; – w is the proportion of predicted Subgroup members who are actually in the Subgroup; and – the subscripts A & B denote Subgroup membership.

Binary ASPES: Step 3: Convert from Predicted to Actual

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  • With the following assumptions…

– AA = AB – BA = BB

  • … we can rearrange the equations to solve for the

unknowns as a function of the knowns:

Binary ASPES: Step 3: Conversion Assumptions

𝐵𝐵 = (𝐽𝐵)(𝑥𝐶) − (1 − 𝑥𝐵)(𝐽𝐶) 𝑥𝐶 + 𝑥𝐵 − 1 𝐶𝐶 = (𝐽𝐶)(𝑥𝐵) − (1 − 𝑥𝐶)(𝐽𝐵) 𝑥𝐶 + 𝑥𝐵 − 1

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SLIDE 75

Abt Associates | pg 74

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Up next: Shawn on ASPES in Practice, with CTI

Illustration

Break 2

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SLIDE 76

Endogenous Subgroup Analysis Using ASPES

Part 3: ASPES in Practice Shawn Moulton Society for Research on Educational Effectiveness Washington, DC | March 2017

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Abt Associates | pg 76

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  • Design requirements
  • ASPES example using data from the Comprehensive

Teacher Induction Study (Glazerman et al., 2010)

  • Introduction to SPI-Path User Guide

ASPES Method in Practice: Outline

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SLIDE 78

Abt Associates | pg 77

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  • ASPES uses data from an experimental evaluation
  • Data must Include:

– Outcome of interest – An indicator for treatment/control status – Measure of the mediator of interest – Baseline data that can be used to model the endogenous subgroups of interest

  • Sufficient Sample Size:

– For Predicted Subgroups: A sample size of at least 560 is needed to detect an effect size of 0.30 or larger – For Actual Subgroups: A sample size of at least 3,380 is needed to detect an effect size of 0.30 or larger (assuming correct placement rates of 65 percent)

Design requirements

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SLIDE 79

Abt Associates | pg 78

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Design requirements
  • ASPES example using data from the

Comprehensive Teacher Induction Study (Glazerman et al., 2010)

  • Introduction to SPI-Path User Guide

ASPES Method in Practice: Outline

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SLIDE 80

Abt Associates | pg 79

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  • In 2004, the U.S. Department of Education’s Institute
  • f Education Sciences contracted with Mathematica

Policy Research to conduct the Comprehensive Teacher Induction (CTI) Study.

  • CTI Study Design: 418 elementary schools in 17

urban districts were assigned by lottery to either:

(1) a treatment group whose beginning teachers were offered comprehensive teacher induction or (2) a control group whose beginning teachers received the district’s “business as usual” induction services

  • See Impacts of Comprehensive Teacher Induction,

Glazerman et al. (2010)

Comprehensive Teacher Induction (CTI) Study

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SLIDE 81

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SREE 2017 | Endogenous Subgroup Analysis Workshop

  • For teachers who received two years of

comprehensive induction:

– There was no impact on student achievement in the first two years – In the third year, there was a positive and statistically significant impact on student math and reading achievement (Glazerman et al., 2010)

CTI Study Findings

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  • One key component of teacher induction programs is

mentorship, or personal guidance from experienced teachers.

  • Mentorship activities include:

– Observing instruction or providing a demonstration lessons; – Reviewing lesson plans, instructional materials, or student work; or – Delivering constructive feedback (Glazerman et al., 2010).

  • Research Question: What role did mentorship play in

improving student achievement outcomes?

ASPES Application using CTI Study Data

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SLIDE 83

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Research Questions and Methods

Research Question Method Used What is the impact of CTI on students taught by teachers who are predicted to receive a high [low] dosage of mentorship? Discrete Version of the ASPES Method (predicted subgroup impacts) What is the impact of CTI on students taught by teachers who receive a high [low] dosage of mentorship? Discrete Version of the ASPES Method (actual subgroup impacts) How does mentorship for beginning teachers influence the impact of CTI on student outcomes? Continuous Version of the ASPES Method

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SLIDE 84

Abt Associates | pg 83

SREE 2017 | Endogenous Subgroup Analysis Workshop

ASPES Stage 1: Predict Mentorship Receipt

  • The first stage of the ASPES analysis involves

employing a strategy that ensures the symmetric prediction of the mediator of interest for the treatment and control groups using baseline covariates.

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CTI Application: Measures

  • Mediator of interest: We constructed a continuously-defined

proxy for mentorship defined as follows:

– The Average Number of Times Teacher was Observed Teaching by Mentor in Past Three Months (Averaged over Fall Year 1, Spring Year 1, Fall Year 2, and Spring Year 2)

  • Baseline characteristics: Teacher background data used for

prediction (e.g., teacher professional backgrounds, current teaching assignments, and demographic characteristics)

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SLIDE 86

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SREE 2017 | Endogenous Subgroup Analysis Workshop

Which baseline characteristics to include in the prediction model?

  • Strategy 1: The “kitchen sink” approach to covariate

selection to achieve “best” prediction

  • Strategy 2: Use empirical approach to select covariates

that are strong predictors of mediator

  • Strategy 3: Include baseline covariates that strongly

predict mediator, but otherwise bear little relationship to impact magnitude

– Seeking “instrumental variables as predictors that affect impact through mediator but not by other means” (Bell and Peck, 2013)

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SREE 2017 | Endogenous Subgroup Analysis Workshop

  • The mediator, which is the outcome of interest in the

prediction model, is defined at the teacher-level.

  • Issue: relatively few degrees of freedom at the

prediction stage (220 teacher-level observations).

  • Implication: must be selective in choosing which

teacher-level covariates to include as covariates at the prediction stage.

  • Solution: use a backward selection procedure to

strategically select the set of covariates included in the prediction model.

CTI Application: Selection of Baseline Covariates for Prediction Model

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SLIDE 88

Baseline Covariates Selected for Inclusion in the Prediction Model Baseline Covariates Considered for Inclusion in the Prediction Model (1) Baseline Covariates Selected for Inclusion in the Prediction Model (2) Teacher Demographic characteristics Age Age-squared ✓ Male teacher Teacher is Hispanic or Latino Teacher is black Teacher is white ✓ Married Any children living in the home Number of children under 18 years in the home Teacher Professional Background Characteristics Has Master’s or Doctoral degree Earned a Bachelor’s degree from a highly selected college Earned a degree with education-related major or minor Entered profession through traditional route ✓ Career changer Late hire during the school year ✓ First year teacher Currently pursuing state certification

Mediator: Average Number of Times Teacher was Observed Teaching By Mentor in Past Three Months

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SLIDE 89

Baseline Covariates Selected for Inclusion in the Prediction Model (Continued) Baseline Covariates Considered for Inclusion in the Prediction Model (1) Baseline Covariates Selected for Inclusion in the Prediction Model (2) Teacher Professional Background Characteristics (Cont.) Any student teaching Number of weeks spent student teaching Current school year salary ✓ Any outstanding student loans Amount of student loans Member of a teacher’s union or professional association ✓ Teacher College Entrance Exams SAT combined score (or ACT equivalent) ✓ SAT math score Teaching Assignments Responsible for reading outcomes Responsible for math outcomes Grade level ✓ Teaching in preferred grade and subject School Characteristics Type of school: K-5, K-6 or K-8 ✓ District ✓ District X Grade ✓

Mediator: Average Number of Times Teacher was Observed Teaching By Mentor in Past Three Months

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SLIDE 90

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SREE 2017 | Endogenous Subgroup Analysis Workshop

ASPES Key Assumption

Δ T 𝑁1𝐵 𝑁1𝑄 X This assumption may be violated if the baseline characteristics X (e.g., teacher salary, SAT scores) used to predict the mediator 𝑁1𝑄 influence the impact Δ through channels other than the actual number of observations 𝑁1𝐵 Assumes no direct or indirect effect

  • f X on Δ

𝑁2𝐵

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Performance of the Prediction Model

Relationship Between Actual and Predicted Mentorship The Average Number of Times Teacher was Observed Teaching By Mentor in Past Three Months (1) Predicted Mediator 0.976*** (0.025) T-Statistic 38.68 Number of Teachers 220 Number of Schools 90 Number of Districts 10 R-Squared 0.871

Sample limited to teachers in the treatment group. Standard errors clustered at the school level. *** p<0.01. Reported sample sizes are rounded to the nearest 10 to minimize disclosure risk.

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Gauging Prediction Success

  • We regressed the Actual Mediator on the Predicted

Mediator for observations in the treatment group.

  • The T-statistic of 38.7 indicates a strong relationship

between the actual and predicted values of the mediator.

  • The regression coefficient of 0.98 indicates that

increasing the predicted mediator by one unit is associated with a 0.98 increase in the actual mediator, representing a near one-to-one correspondence.

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SLIDE 93

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Research Questions and Methods

Research Question Method Used What is the impact of CTI on students taught by teachers who are predicted to receive a high [low] dosage of mentorship? Discrete Version of the ASPES Method (predicted subgroup impacts)

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For discrete ASPES method: Define Subgroups of Interest

  • Create “interesting” subgroups
  • Ensure sufficient sample sizes in each predicted

subgroup

  • In the CTI Study application:

– Predicted high dosage subgroup includes teachers in the treatment and control groups who are predicted to receive at least the median dose of mentorship – Predicted low dosage subgroup includes teachers predicted to receive less than the median dose of mentorship

  • Percent of treatment group members predicted to be

in their true subgroup (correct placement rate): 73 percent

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Abt Associates | pg 94

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Stage 2: Estimate Impacts on Predicted Subgroups

Treatment Control

Predicted High Dosage Predicted Low Dosage Predicted High Dosage Predicted Low Dosage

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Impacts on Predicted Subgroups

Math Achievement Reading Achievement CTI Study Impact for pooled sample 0.20*** 0.11** Predicted High Dosage Subgroup 0.360*** (0.096) 0.241*** (0.078) Predicted Low Dosage Subgroup

  • 0.020

(0.092)

  • 0.138

(0.112) Notes: *p<0.10, ** p<0.05, *** p<0.01. CTI Study Impact from Glazerman et al. (2010).

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  • The CTI intervention had a large positive impact on

math and reading achievement for students taught by teachers most likely to receive a high dosage of mentorship.

  • No effect on students taught be teachers who are

predicted to receive comparatively little mentorship.

  • Impacts on the predicted high dosage subgroup are

larger in magnitude than CTI Impacts using the full sample.

Impacts on Predicted Subgroups: Summary of Findings

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SLIDE 98

Abt Associates | pg 97

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  • Predicted subgroup impacts:

– Are asymptotically unbiased (Harvill, Peck & Bell, 2013) – Not everyone in the predicted high dosage subgroup actually received a high dosage – Provide estimate of CTI’s impact on students taught by teachers who are most likely to receive a high (or low) dosage of mentorship

  • Researchers may be more interested in impacts on

actual subgroups (e.g., those who actually received a high dosage of mentorship)

Predicted Subgroup Impacts Vs. Actual Subgroup Impacts

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SLIDE 99

Abt Associates | pg 98

SREE 2017 | Endogenous Subgroup Analysis Workshop

Research Questions and Methods

Research Question Method Used What is the impact of CTI on students taught by teachers who receive a high [low] dosage of mentorship? Discrete Version of the ASPES Method (actual subgroup impacts)

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SLIDE 100

Abt Associates | pg 99

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Stage 3: Convert from Predicted to Actual Impacts

Treatment Control

Actual High Dosage Actual Low Dosage Actual High Dosage Actual Low Dosage

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SLIDE 101

Abt Associates | pg 100

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Comparison to Impacts on Actual High Dosage Subgroup

Math Achievement Reading Achievement CTI Study Impact for pooled sample 0.20*** 0.11** Predicted High Dosage Subgroup 0.360*** (0.096) 0.241*** (0.078) Actual High Dosage Subgroup 0.691*** (0.197) 0.504*** (0.153) Notes: *p<0.10, ** p<0.05, *** p<0.01. CTI Study Impact from Glazerman et al. (2010).

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  • Impacts on actual high dosage subgroup is larger in

magnitude than CTI Study impacts and predicted subgroup impacts.

  • Standard errors on actual high dosage subgroup

impacts are large, limiting our ability to reject more modest effects.

  • Unbelievably large impacts on actual subgroups may

indicate that ASPES conversation assumptions are not satisfied

Comparison to Impacts on Actual High Dosage Subgroup: Summary of Findings

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  • Often greater interest in impacts on actual subgroups
  • Requires additional assumptions to be considered

asymptotically unbiased

  • Requires larger sample sizes

Predicted Subgroup Impacts Vs. Actual Subgroup Impacts

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SLIDE 104

Abt Associates | pg 103

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Research Questions and Methods

Research Question Method Used How does mentorship for beginning teachers influence the impact of CTI on student outcomes? Continuous Version of the ASPES Method

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Abt Associates | pg 104

SREE 2017 | Endogenous Subgroup Analysis Workshop

Stage 2: Impact Model

  • Estimate the Relationship between the Predicted Mediator and

Effect Size: Y= β0 + β1 𝑁 𝑄+ β2T + β3T 𝑁 𝑄+𝜁2 – 𝑍 is the outcome being examined; – 𝑁 𝑄 is the predicted value of the mediator generated from Stage 1; – 𝑈 indicates whether the member was assigned to the treatment or control group; and – 𝜁2 is an error term that captures all other factors that influence the outcome.

  • The impact of being assigned to the treatment group is given by

the following equation:

𝜖𝑍 𝜖𝑈 = 𝛾2 + 𝛾3𝑁

𝑄

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Abt Associates | pg 105

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The effect of mentorship on the impact of CTI

Math Achievement Reading Achievement The Average Number of Times Teacher was Observed Teaching By Mentor in Past Three Months 0.266** (0.109) 0.278*** (0.088) Notes: *p<0.10, ** p<0.05, *** p<0.01.

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Abt Associates | pg 106

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  • A one unit increase in the Average Number of Times

Teacher was Observed Teaching By Mentor in Past Three Months is akin to jumping from the ~25th percentile to the 75th percentile in terms of the amount of mentorship received

  • This increase in mentorship is associated with a

large increase in the impact of CTI on both math and reading achievement

– Boosts the CTI Impact on math by 27 percent of a standard deviation – Boosts the CTI Impact on reading by 28 percent of a standard deviation

The effect of mentorship on the impact of CTI: Summary of Findings

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Abt Associates | pg 107

SREE 2017 | Endogenous Subgroup Analysis Workshop

  • Design requirements
  • ASPES example using data from the Comprehensive

Teacher Induction Study (Glazerman et al., 2010)

  • Introduction to SPI-Path User Guide

ASPES Method in Practice: Outline

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  • Describes the ASPES method in detail
  • Includes SAS and Stata code for conducting analysis
  • Provides sample table shells and interpretation

assistance

  • Practical considerations and examples from literature

throughout

Social Policy Impact Pathfinder (SPI- Path) User Guide

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SLIDE 110

Abt Associates | pg 109

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  • Download User Guide:

– http://abtassociates.com/Our-Work/Tools/SPI-Path.aspx

  • Stay in touch:

– Eleanor_Harvill@abtassoc.com (301) 347-5638 – Shawn_Moulton@abtassoc.com (617) 520-2459 – Laura_Peck@abtassoc.com (301) 347-5537