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ISBT WORKING PARTY ON RARE DONORS Iran Iranian Blood Transfusion - PowerPoint PPT Presentation

Sep 24, 2022 •256 likes •360 views

ISBT WORKING PARTY ON RARE DONORS Iran Iranian Blood Transfusion Organization Established in 1974 A centralized National organization responsible for countrys blood bank / blood transfusion requirements Iranian National Rare Donor

  1. ISBT WORKING PARTY ON RARE DONORS Iran Iranian Blood Transfusion Organization Established in 1974 • A centralized National organization responsible for country’s blood bank / blood transfusion requirements Iranian National Rare Donor Program established in 2009 Testing Education Collection Storage Recruitments & Distribution preparation

  2. ISBT WORKING PARTY ON RARE DONORS Iran Rare blood donor is defined as: One which lacks a high-frequency antigen One with multiple – common – antigen negative One with a low- frequency antigen One in 1000,5000, 10000 &more Rare Blood Database Number of donors up to June 2012 470 Number of frozen Rare cells for Transfusion up to June 2012 73 Number of Rare Donor unit used 2012 6 2011 8 2010 3 ( 1 Autologous ) ( 2 Allogeneic ) 2009 0

  3. ISBT WORKING PARTY ON RARE DONORS Iran 5000-10000 Random donor 31 IBTO samples annual • Education Provincial Blood Retention • Public Donor Centers Rare Donor I mmunohematology Relation Reference Patient Phenotype • Recalling Hospital Blood Effective samples detection Laboratory for continuous Bank Automation + Manual donation relation Laboratory Method 2 times per year by Frozen Blood Tel. contact Other Medical Patient • Updating Department Centers samples processing & personal Infertility , storage information thalassemia , closed system Bone Marrow & transplantation

  4. ISBT WORKING PARTY ON RARE DONORS Iran Most challenging type to find Antigen frequency Out come Type of individual 1:2000 Survived ( E-c- K-Jk (b- Pregnant patient Pregnant patient 1:10000 ( E-c-Jk(b-)Fy(b- Survived 1:25000 C-K-Jk(b-)S-M- Died Thalassemia patient Kidney transplant E- C- c- e- 1: 19,000,000 Waiting list candidate D¯¯ Potent Auto anti-I rare Died Thalassemia titer >1000

  6. ISBT WORKING PARTY ON RARE DONORS Iran Rare Blood Donors Identified /Bombay (O h ) phenotype # of ABO& Rh Male Female Geographic area Individual Range of age Average frozen Misc type year age /year unit Donor O/ Rh (D) Center-East One 9 5 28-50 41 8 Positive North- South patient /Donor O/ Rh (D) Center - North 2 4 30-50 38 6 Negative East 1 patient Patient O/ Rh (D) (80 years) Center-south Positive 3 6 2-80 56 0 died after East receiving 6 units of RBCs O/ Rh (D) 1 Center 56 56 0 Negative

  7. ISBT WORKING PARTY ON RARE DONORS Iran Total number of Bombay individual 30 Frequency in Iranian Population June 2012 1:2,500,000 Donor /patient ratio 2:1 Number of cases identified per year 2012 4 2011 10 2010 10 2009 6

  8. ISBT WORKING PARTY ON RARE DONORS Iran Transition in Rare blood detection and preparation Manual method Automation Molecular typing

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