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Interconnected and Interdependent Anticipating Infectious Disease Risks in an Increasingly Mobile World ACRP Insight Event March 6 th 2018 Kamran Khan MD, MPH Division of Infectious Diseases St. Michaels Hospital Associate Professor


  1. Interconnected and Interdependent Anticipating Infectious Disease Risks in an Increasingly Mobile World ACRP Insight Event March 6 th 2018 Kamran Khan MD, MPH Division of Infectious Diseases St. Michael’s Hospital Associate Professor Faculty of Medicine Dalla Lana School of Public Health University of Toronto Founder, BlueDot

  2. 6 751 393 674 603 KM 22 000+ Round Trips

  3. Trends in Global Air Travel Distance Traveled Worldwide via Commercial Flights 5 +60% Domestic 4.5 International 3.75 Trillions of Kms Traveled 2.8 +53% 2.5 2.2 1.5 1.25 0 2007 2016

  4. 14.3% Global Share 0 1 6 e l e d i n 2 a l K m T r a v e r n a t i o n o f I n t USA 6.3% 25% of the world’s mobility via air comes from just three countries UK 4.9% China Rest of the World 51.5% Germany 3.8% Spain 3.7% J a p a n Nearly 50% of the world’s Australia mobility via air comes 3.4% France from just ten countries Canada I n d 3.3% i a 3.1% 2.8% 2.9%

  5. Billions of KM traveled on Connected Cities international flights in 2016 1 London 398 2 New York 261 3 Paris 212 4 Tokyo 181 5 Bangkok 169 6 Hong Kong 162 7 Los Angeles 162 8 Seoul 156 9 Singapore 151 10 Dubai 138 11 Shanghai 131 12 Sydney 115 13 Beijing 110 14 Frankfurt 105 15 San Francisco 102 16 Amsterdam 97 17 Toronto 93 18 Taipei 91 19 Manila 90 20 Madrid 86 These 20 cities account for one-third of the international distance traveled worldwide in 2016

  6. D i s e a s e s S p r e a d F a s t . I n s i g h t s C a n S p r e a d F a s t e r .

  7. Artificial Intelligence Human Intelligence

  8. Public Health Healthcare The Public

  9. Anticipating the International Spread of Zika

  10. Anticipating the International Spread of Zika

  11. Anticipating the International Spread of Zika Bogoch I.B. et al. Lancet 2016; 387(10016): 335-6

  12. Network Architecture and Flows 1 2 X Peer Review Khan K et al. Bull WHO 2013; 91: 368-376

  13. Fig. 5. Evidence-based decision-support tool for cities at risk of the importation of a pathogen causing infectious disease Global area(s) with community-based epidemic activity Effective exit screening implemented? Yes No Non-stop flights arriving Non-stop flights arriving directly from affected area? directly from affected area? 2.114777 Yes No Yes No Infectious agent with short incubation period? Yes No Evaluate role of Evaluate role of Screening of travellers Evaluate role of entry Screening of travellers entry screening entry screening not suggested screening not suggested Heighten local infectious disease surveillance and mobilize resources for public-health control Khan K et al. Bull WHO 2013; 91: 368-376

  14. Public Health Healthcare The Public

  15. George Health Companion for Travelers

  16. Thank You Kamran Khan MD, MPH Division of Infectious Diseases St. Michael’s Hospital Associate Professor Faculty of Medicine Dalla Lana School of Public Health University of Toronto Founder, BlueDot

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