In Search of Synergy: Multilevel Implementation Interventions - - PowerPoint PPT Presentation

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In Search of Synergy: Multilevel Implementation Interventions - - PowerPoint PPT Presentation

In Search of Synergy: Multilevel Implementation Interventions Bryan J. Weiner, Ph.D. You think because you understand 'one' you must also understand 'two', because one and one make two. But you must also understand 'and'. ~ Rumi GOT


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In Search of Synergy: Multilevel Implementation Interventions

Bryan J. Weiner, Ph.D.

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You think because you understand 'one' you must also understand 'two', because one and one make two. But you must also understand 'and'. ~ Rumi

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GOT SYNERGY?

  • Implementation facilitators and barriers operate at

multiple levels of influence

  • Yet, multi-level implementation interventions often don’t

work better than single-level ones Why?

  • Selected implementation interventions do not target key

determinants of the problem

  • Interdependence of key determinants of the problem are

poorly understood

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THE CAUSAL LOGIC OF MULTILEVEL INTERVENTION

We explored how interventions at different levels could be combined to produce complementary or synergistic effects …using a causal modeling framework to develop potential combinations We concentrated on two forms

  • f causal interdependence:

mediation and moderation …and identified 5 potentially useful strategies for combining interventions at different levels

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MEDIATION Mediator: A variable that explains (or accounts for) the relationship between the dependent variable and the independent variable.

5

IV M DV

Full Mediation

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MEDIATION Mediator: A variable that explains (or accounts for) the relationship between the dependent variable and the independent variable

IV M DV

Partial Mediation

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MEDIATION Mediator: a variable that explains (or accounts for) the relationship between the dependent variable and the independent variable

IV M DV

Parallel Mediation

M

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MEDIATION

8

IV M DV

Serial Mediation

M

Mediator: A variable that explains (or accounts for) the relationship between the dependent variable and the independent variable.

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MODERATION Moderator: A variable that changes the strength of an effect or relationship between two variables.

IV W DV

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MODERATION Moderator: A variable that changes the strength of an effect or relationship between two variables.

IV W DV W

Multiple Moderation

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MODERATION Moderator: A variable that changes the strength of an effect or relationship between two variables.

IV W DV W

Moderated moderation

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COMBINATIONS Moderated mediation: Mediating process or pathway is intensified or attenuated by individual difference or contextual condition.

IV M DV W W

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SOCIAL ECOLOGICAL MODEL Levels as Settings*

* Or social units

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SOCIAL ECOLOGICAL MODEL Levels as Determinants

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Example: Possible Barriers to or Determinants of Colorectal Cancer Screening

Level of Influence Possible Barrier/Determinant Intervention Strategy

Intrapersonal

  • Patient/provider knowledge, attitudes, beliefs
  • Patient structural barriers (e.g., time, money)
  • Inadequate cues to action
  • Education, training, navigation
  • Decision support
  • Reminders

Interpersonal

  • Poor physician-patient communication
  • Inadequate social/spousal support
  • Professional (social) norms about screening
  • Communication
  • Shared decision making
  • Social support
  • Opinion leaders

Organizational

  • Poor care coordination, inefficient processes
  • Inadequate staffing, inadequate data systems
  • Quality improvement
  • Service/staffing changes
  • Role revisions, registries

Community

  • Low community awareness/demand
  • Inadequate supply of diagnostic colonoscopy

services

  • Social marketing campaign
  • Assisted transportation services

Macro Policy

  • Limited or lack of insurance coverage
  • Inadequate incentives to coordinate care
  • Insurance coverage changes
  • Bundled payment policies
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  • 1. ACCUMULATION STRATEGY

Legend Box: intervention and level of influence (in parentheses) Diamond: mediator Oval: outcome

Public reporting* (organizational) Op Opinion Leader (I (Interpersonal) Outreach visit (Intrapersonal)) Physician’s motivation Colorectal Cancer Screening *For expositional purposes, the diagram depicts interventions rather than determinants as causes. To keep the concept simple, a single mediating pathway is presented.

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  • 2. AMPLIFICATION STRATEGY

Public reporting* (Organizational) Opinion leader (Interpersonal) Audit and feedback (Intrapersonal) Physician’s motivation Colorectal Cancer Screening

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  • 3. FACILITATION STRATEGY

Public reporting* (Organizational) Opinion leader (Interpersonal) Clinical reminder (Intrapersonal) Physician’s motivation Colorectal Cancer Screening

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  • 4. CASCADE STRATEGY

Office systems

Colorectal Cancer Screening

Quality improvement (Organizational) Physician motivation Outreach visit (Intrapersonal) Manager motivation Advocacy at state level (Macro Policy)

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  • 5. CONVERGENCE STRATEGY

Public reporting* (Organizational) Opinion leader (Interpersonal) Patient education (Intrapersonal) Physician motivation Colorectal Cancer Screening Patient motivation Provider- patient interaction

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AMPLIFICATION STRATEGY

Clinician’s motivation Participation in Training Incentives (Intrapersonal) Social norms Opinion leader (Interpersonal)

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WHAT’S NEEDED

> Multilevel theories that explain how determinants at multiple levels interact to produce health and other

  • utcomes

> Cross-level research that examines the inter-dependence of variables (determinants) at multiple levels of influence > Knowledge of the causal mechanisms through which commonly employed implementation interventions produce their effects