IDUN Intelligent oral Drug delivery Using Nano and microfabricated - - PowerPoint PPT Presentation

▶

Mar 28, 2024 171 likes •235 views

IDUN Intelligent oral Drug delivery Using Nano and microfabricated containers The Team Motivation and Perspectives Monodispersity and customised dosage Control of release kinetics and place Stabilize drugs Adhesion and unidirectional

SLIDE 1

IDUN – Intelligent oral Drug delivery Using Nano and microfabricated containers – The Team

SLIDE 2

Motivation and Perspectives

Adhesion and unidirectional release in intestine Protection in stomach Control of release kinetics and place Monodispersity and customised dosage Combine drugs, permeation enhancers etc Stabilize drugs

SLIDE 3

Idea and novelty

SLIDE 4

Structure/activities

Container design optimization Reservoir and lid Surface structuring/coating

A Polymer and drug layer deposition Embossing tool Release and collection

f micropatches

Embossing tool Barrier layer Release layer Mucoadhesive drug matrix Handling layer Controlled release coating B D C B C D

Biocompatible micro-containers Loading of drugs Microsystem for in vitro characterization In vitro and in vivo studies

1. 2. 3. 4. 5 6. 7.

SLIDE 5

New results

Intestinal perfusion In vivo studies

Biocomp. container

100 µm

a) b)