Ia Iatr trogenic ogenic bile duct bile duct injur injury Eduard - - PowerPoint PPT Presentation

ia iatr trogenic ogenic bile duct bile duct injur injury
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Ia Iatr trogenic ogenic bile duct bile duct injur injury Eduard - - PowerPoint PPT Presentation

Ia Iatr trogenic ogenic bile duct bile duct injur injury Eduard Jonas Surgical Gastroenterology Unit University of Cape Town and Groote Schuur Hospital Cape Town, South Africa Conflict of Interest I declare I have no conflict of interest


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Ia Iatr trogenic

  • genic bile duct

bile duct injur injury

Eduard Jonas

Surgical Gastroenterology Unit University of Cape Town and Groote Schuur Hospital Cape Town, South Africa

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SLIDE 2

Conflict of Interest

I declare I have no conflict of interest

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SLIDE 3

Social Media

You are welcome to share details of this presentation responsibly and with due credit on social media.

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Bile duct injury (BDI)

  • Significant associated

morbidity and mortality

  • Significantly increasing

cost of treatment

  • Common causes of

litigation in general surgery

  • It severely decreases QOL

for the patient

“ ”

OC era1 0.20% “Learning curve” 2-4 0.3% – 0.82% Beyond the curve5,6 0.22% – 0.4%

BDI incidence Time

1 Roslyn et al. Ann Surg. 1993;218(2):129-37 2 Nuzzo et al. Arch Surg. 2005;140(10):986-92 3 Karvonen et al. Surg Endosc. 2011;25(9):2906-10 4 Tornqvist et al. BMJ. 2012;345:e6457 5 Barret et al. Surg Endosc. 2018;32:1683-88 6 Fong et al. JACS. 2018;226(4):568-76

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Classification

Strasberg ATOM

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Management

Spectrum of deranged physiology Time of detection

– Intraoperative – Post-operative – Late

Timing of repair

– Immediate – Early – Delayed – Late

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Patient case 1

  • 45 year old male presented to peripheral hospital (100

km away) with sudden onset abdominal pain

  • early cholecystitis - laparoscopic cholecystectomy
  • telephone call from theatre

– divided cystic duct – divided cystic artery – dissecting gallbladder - encountered and severed another duct

  • What now?
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Management options

  • Repair by the injuring surgeon
  • Experienced surgeon travel to do repair
  • Immediate referral to a specialist center
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Injuring surgeon repair

Stewart L, et al. Arch Surg. 1995 Oct;130:1123-8 Carroll BJ, et al. Surg Endosc. 1998;12:310-3

Successful long-term outcome

Primary surgeon repair - 27% Referred patients - 79%

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(Travel) immediate repair

  • Not playing a home match
  • Suboptimal conditions
  • Extent of the injury may not be

evident

  • Limited investigation possibilities
  • Creating more havoc looking for

the missing parts in the puzzle

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Immediate repair

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Referral to specialist center

Advice to injuring surgeon

  • Stop operating!
  • Control/exteriorize the leak
  • Closed (suction) drain
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Work-up

  • Physiology of the patient
  • Extent of the bile duct injury
  • Associated vascular injury
  • Free fluid / fluid collections
  • Status of the liver
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Imaging

  • Cross-sectional imaging

– CE-MDCT – CE-MRI / MRCP

  • Interventional imaging

– ERCP – PTC

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CE-MDCT

  • Dilated bile ducts

(cholangiogram)

  • Free fluid
  • Vascular injury
  • Perfusion defects
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99mTc-IDA

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CE-MRI/MRCP

T2-weighted T1-weighted

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PTC?

  • Diagnostic information
  • Obstructed duct decompression
  • Act as infra-hepatic drain
  • Facilitate intra-operative

identification of bile ducts

  • Decompression of peri-

anastomotic duct

  • Allows post-reconstruction

imaging

  • Definitive management?
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Patient case 1 cont.

  • Clinically well
  • Soft abdomen
  • WCC slightly raised
  • LFTs minimally deranged
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Patient case 1 cont.

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Surgery

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Technique

  • Minimal dissection especially behind ducts
  • Tension free mucosa to mucosa anastomosis

to well perfused duct

  • Hepaticojejunostomy preferred
  • Proximal anastomosis
  • Hepp-Couinaud approach
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Technique

Atlas of Upper Gastrointestinaland Hepato-Pancreato-Biliary Surgery. Springer-Verlag Berlin Heidelberg 2007

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Technique

Atlas of Upper Gastrointestinaland Hepato-Pancreato-Biliary Surgery. Springer-Verlag Berlin Heidelberg 2007

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Intra-operative PTC

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Postoperative course

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Coexistence of anomalies

With arterial anomalies (non-Michel 1) approximately 70% of patients will have some form biliary anomaly Absent RHD 35% RPSD drains into LHD 20% RPSD low insertion 20%

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Patient case 2

  • 33-year-old morbidly obese female BMI 53
  • elective laparoscopic cholecystectomy
  • BDI diagnosed on post-operative day 22
  • laparotomy with washout and drainage
  • arrived on day 28 post-injury
  • uncontrolled sepsis
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Patient case 2 cont.

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Patient case 2 cont.

Lindemann J, et al. Int J Surg Case Rep. 2019;60:340-344

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Patient case 2 cont.

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Patient case 2 cont.

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Patient case 2 cont.

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Timing of repair

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Summary

  • Multidisciplinary management
  • Individualize patient treatment
  • Manage the patient
  • Optimal pe-operative information
  • Correct physiology and nutritional status
  • Early repair preferable, delay when necessary