SLIDE 1
Confession
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
Human Embryonic Stem Cell Treatment An Indian Perspective - - PowerPoint PPT Presentation
Human Embryonic Stem Cell Treatment An Indian Perspective - - PowerPoint PPT Presentation
Human Embryonic Stem Cell Treatment An Indian Perspective Presentation by Dr Geeta Shroff 15 March 2013 Kings College, London Presentation by Dr Geeta Shroff Human Embryonic Stem Cell Treatment 15 March 2013 Kings College, London
SLIDE 2
SLIDE 3
Specialist in fertility and IVF techniques
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 4
Five-step process
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 5
The accident
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 6
The accident repeated
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 7
Stem cells
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 8
Established stem cell lines
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 9
Regulations and guidelines
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 10
Continuous iteration
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 11
No ban
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 12
Recommendations may change with time
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 13
Enabling structure
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 14
Product acceptance and release criteria
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 15
IC-SCRT / NAC-SCRT
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 16
Records, no hype, scientific evidence
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 17
Data for over 1,200 patients
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 18
GLP, GMP and GCP certifications
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 19
Regulatory environment
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 20
France
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 21
Germany
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 22
Italy
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 23
The UK
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 24
China
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 25
The USA
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 26
National Institutes of Health Guidelines on Human Stem Cell Research
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 27
Singapore
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 28
No specific legislation in Singapore
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 29
Singapore chimeras
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 30
What have I done differently?
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 31
Only one embryo
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 32
Non-chimeric
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 33
Treatment outcomes
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 34
Assessment standards and scales
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 35
Holistic, sensitive and workable score
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 36
Some cases
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 37
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 38
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
2 June 2011 11 November 2011
SLIDE 39
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
19 June 2012 16 July 2012
SLIDE 40
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
16 July 2012 2 June 2011
SLIDE 41
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 42
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 43
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 44
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
After Before
SLIDE 45
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 46
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
8 November 2011 3 January 2012
SLIDE 47
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
7 March 2012 6 November 2012
SLIDE 48
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
6 November 2012 8 November 2011
SLIDE 49
45-year old female
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
Day 10 Day 2
SLIDE 50
45-year old female
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
Day 26 Day 19
SLIDE 51
45-year old female
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
Day 26 Day 1
SLIDE 52
Ready-to-use form
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 53
International patent
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 54
Easy clinical application
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 55
Incurable and chronic conditions and illnesses
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 56
Treatment protocol developed over the years
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 57
30% are doctors, 30% from 36 countries
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 58
Towards commercialisation
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 59
Virtual patent ban in the EU
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 60
How can innovation come from the third world?
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 61
Two basic questions
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 62
When does a developing embryo become human?
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 63
Questions only for hESC research and treatment
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 64
No problems with IVF
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 65
Wastage of nearly 1.7 million embryos in the UK
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 66
Termination of pregnancy
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 67
Morning-after pill acceptable
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 68
Safe and efficacious therapeutic effects
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 69
No matching, no testing
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 70
First line of treatment for many of mankind’s worst afflictions
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 71
Cogent, unblinkered policy framework
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 72
What lies ahead is still not firm and final
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 73
Review, accept and adapt
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 74
Thinking of the patient first
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 75
No more Savitas
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 76
Death triumphed where life should have
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 77
It is time we acted
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London
SLIDE 78
Thank you!
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff
15 March 2013 • King’s College, London