Epithelial Response to Parasitic Infections Thibaut de Sablet, Ph.D. - - PowerPoint PPT Presentation
Epithelial Response to Parasitic Infections Thibaut de Sablet, Ph.D. BACKGROUND 2004-2007 PhD on Enterohaemorrhagic E. coli INRA Clermont-Ferrand 2008-2013 Post Doctoral Fellowship on Helicobacter pylori and Gastric Cancer Vanderbilt University
Thibaut de Sablet, Ph.D.
2004-2007 PhD on Enterohaemorrhagic E. coli
INRA Clermont-Ferrand
2008-2013 Post Doctoral Fellowship on
Helicobacter pylori and Gastric Cancer Vanderbilt University Nashville TN
2014-2015 Agreenskills Post Doctoral
Fellowship on Crypstosporidium parvum and Epithelial Cells INRA Nouzilly
The principal clinical manifestation is a watery diarrhea in young calves that can lead to dehydration and ultimately death of the infected animals No vaccine, limited chemotherapy. First cause of neonatal diarrheal disease (ruminants).
Highly prevalent in cattle in France (40-60%). Economical loss for beef and dairy industry
Zoonosis: 748 000 case/year US In developing countries: 8-19% of diarrheal disease In developped countries: 1-3% High prevalence in immunocompromised individuals; responsible for 25% of chronic diarrhea One Health issue: by controlling and understanding cattle infection we would be able to control human infection.