Does Parkinsons disease impact habitual actions? Parkinsons NSW - - PowerPoint PPT Presentation

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does parkinson s disease impact habitual actions

Does Parkinsons disease impact habitual actions? Parkinsons NSW - - PowerPoint PPT Presentation

Nov 16, 2022 362 likes •622 views

Does Parkinsons disease impact habitual actions? Parkinsons NSW Public Forum Dr Teri Furlong Neuroscience Research Australia Non-motor symptoms: thinking and memory Difficulty paying attention Difficulty concentrating Slowness of

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Does Parkinson’s disease impact habitual actions?

Parkinson’s NSW Public Forum

Dr Teri Furlong

Neuroscience Research Australia

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Difficulty paying attention Difficulty concentrating Slowness of thinking Difficulty multi-tasking or task switching

Non-motor symptoms: thinking and memory

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Dopamine neurons (brain cells) in the substania nigra Biggest impact

n the putamen

Healthy Parkinson’s disease

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Habits are good! Habits allow you to automate behaviour and multi-task Habits depend on the putamen Do people with PD have trouble learning habits?

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How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 8

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 9

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 10

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 11

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 12

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 13

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 14

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 15

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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SLIDE 16

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

slide-17

SLIDE 17

How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

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How do you measure habits?

Habitual actions are

automated

Goal-directed actions

require thinking about consequences

Habitual action Goal-directed action

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Repeated actions lead to habits No habits without dopamine

Habitual action Goal-directed action

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Repeated actions lead to habits No habits without dopamine

Habitual action Goal-directed action

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Repeated actions lead to habits No habits without dopamine

Habitual action Goal-directed action

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Next steps

Determine whether

humans have trouble developing habits

Determine if current

medications help restore habits (e.g., L-dopa)

Chemogenetics

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chemogenetics

Insert receptors into brain cells
Receptors are responsive to a

special chemical

Consume chemical in a tablet
Activate the putamen

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Summa mmary

Repeated actions lead to habits No habits without dopamine Can chemo- genetics restore habits?

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Does Parkinson’s disease impact habitual actions?

Parkinson’s NSW Public Forum

Dr Teri Furlong

Neuroscience Research Australia