Disease Monitoring James W. Stark, MD, FAAN TISCH MS RESEARCH - PowerPoint PPT Presentation

Sep 30, 2022 •293 likes •410 views

Disease Monitoring James W. Stark, MD, FAAN TISCH MS RESEARCH CENTER OF NEW YORK 22 ND ANNUAL PATIENT SYMPOSIUM Timeline of MS Disease Modifying Therapies 1980s 1990s 2000s 2010s Future Gilenya Ibudilast Aubagio Novantrone

Disease Monitoring James W. Stark, MD, FAAN TISCH MS RESEARCH CENTER OF NEW YORK 22 ND ANNUAL PATIENT SYMPOSIUM
Timeline of MS Disease Modifying Therapies 1980’s 1990’s 2000’s 2010’s Future Gilenya Ibudilast Aubagio Novantrone Betaseron Tecfidera Ponesimod Rebif ? Plegridy Ozanimod Avonex Lemtrada Tysabri Ofatumumab Ocrevus Copaxone Masitinib Extavia Mayzent Mavenclad
No Evidence of Disease Activity
NEDA No New Symptoms No Physical Exam Changes No MRI Changes Is There More?
What is a Relapse? Blurred Vision Bladder and Bowel Double Vision Weakness Numbness Loss of Balance
Relapse vs Pseudorelapse? Constant Intermittent New Old Focal Generalized
MRI Change in Lesions Contrast Enhancement Neuroquant
Other Testing Cognitive Testing Neurofilament Light Chain Optical Coherence Tomography
NEDA = Disease Control Conclusion NEDA is achievable!!! No Evidence of Need to monitor even without symptoms Disease Activity Doesn’t matter which drug Early effective treatment
THANK YOU! JAMES W. STARK, MD, FAAN

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