DEVICE, FOR TREATING PAIN AND ITS SOURCE AT HOME ABOUT GOOD - PowerPoint PPT Presentation

B-CURE LASER IS AN EFFECTIVE, CLINICALLY PROVEN MEDICAL DEVICE, FOR TREATING PAIN AND ITS SOURCE AT HOME

ABOUT GOOD ENERGIES

KEY HIGHLIGHTS GOOD ENERGIES ERIKA CARMEL LTD. MANAGEMENT THE COMPANY THE FOUNDERS +100 EMPLOYEES SUPPORTS Michael and Zipi Schlosser founded at our headquarters in Haifa and at our call an international distributing partner Erika Carmel Ltd. (B-Cure Laser) in 2008. center in Rishon LeZion, Israel network for global access

OUR VISION To lead through the development and marketing of innovative and advanced therapeutic products in the fields of orthopedic conditions, pain, wounds and dermatology. We strive to improve patient quality of life, by shortening the healing process and improve patient wellbeing.

OUR PROMISE To spread Good Energies with the right partners around the world!

“ OUR INSPIRATION “ The secret of change is to focus all of your energy not on fighting the old, but on building the new - Socrates

ABOUT B-CURE LASER

EFFECTIVE, CLINICALLY PROVEN AND SAFE treatment for pain, orthopedic conditions and wounds

OUR PRODUCTS

B-CURE LASER SERIES PROFESSIONAL AND HOME USE

THE ADJUSTABLE STAND REACHING YOUR PAIN EVERYWHERE AND ANYWHERE! A flexible, adjustable stand enables convenient and effective treatment, without having to actually hold the B-Cure Laser with your hands.

HOW DOES THE B-CURE LASER WORK? Increases the Stimulates cell Releases Stimulates blood and Increases the formation Increases efficiency of production of ATP that activity & strengthens cell endorphins that lymph flow that reduce of collagen & elastin, the body ’ s natural signals that relieve pain, fight relieve pain accelerates wound edema and accelerate that accelerates wound immune system healing and fights chronic inflammation and wound healing healing accelerate wound healing chronic inflammation

B-CURE LASER ESSENTIAL IN EVERY HOME ONE MEDICAL DEVICE THAT HELPS THE WHOLE FAMILY

MARKET OVERVIEW

PAIN AND WOUND MANAGEMENT GLOBAL MARKET Pain Relief Wound Care The global pain relief The global wound care market is estimated to market is estimated to reach $79B revenue by reach $42B revenue by 2024 (4% CAGR) 2024 (6.2% CAGR) $79B $42B

PAIN AND WOUND MANAGEMENT TRADITIONAL CARE Dressings Painkillers Others Advanced dressings include silver Prescription of painkiller medication Physiotherapy, electrotherapy, shock dressings and combination dressings is one of the most popular ways to wave therapy, acupuncture and which consist of an anti-microbial deal with pain. However, clinical other forms of treatment, might add agent. research is raising public awareness extra discomfort to an already to the severe related side effects. suffering patient. Requires patients to invest time and effort in traveling to specialized clinics.

A NEW SURVEY ON CHRONIC PAIN A survey on chronic pain, performed in 17 European countries (n=3490), indicates that approx. 20% of the adult population in Europe (95 million) , suffers from chronic pain. Pain Alliance Europe (PAE) , 2017 78% 34% of the of the patients who received traditional treatment, patients suffering from chronic pain reported that it was not as effective as describe their pain as ‘ severe ’ expected

DISADVANTAGES OF PAINKILLERS In recent years there has been a push by regulatory agencies such as the FDA towards medical devices, characterized by less intensive side effects than painkillers , such as opioids. 50 212 thousand million Americans died from opioid-related drug opioid prescriptions in the USA overdoses in the USA in 2017 in 2017

PROVEN RESULTS

SYSTEMATIC LITERATURE REVIEW Therapeutic efficacy of home-use photobiomodulation devices: a systematic literature review Gavish L., Faculty of Medicine, The Hebrew University of Jerusalem , Israel; Houreld N., Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa B-Cure Laser was cited in 4 out of 14 studies according to the systematic review published in the magazine "Photomedicine and Laser Surgery" (November 2018). The systematic literature supports the outstanding efficacy of B-Cure Laser vs. all medical photomedicine devices for home use worldwide, for the treatment of pain and wound healing. 29% of the patients in the literature review received B-Cure Laser therapy treatments

PROFESSIONAL RECOMMENDATIONS American College of Physicians ’ “ We show that LLLT reduces pain International guidelines recommend guidelines include a “ strong immediately after treatment in the " use of low level laser therapy recommendation ” for Low-Level acute neck pain and up to 22 weeks for treatment of Oral Mucositis " Laser Therapy as a non invasive after completion of treatment in (November 2018) treatment for acute, subacute & patients with chronic neck pain. ” chronic low back pain (December 2009) (April 2017)

B-CURE LASER ’ S Del Vecchio A., Fioravanti M., Boccassini A., Di Paolo C., Romeo U. EFFICACY IS ALMOST Department of Oral and Maxillo Facial Sciences | Sapienza University of Rome, Italy EQUIVALENT TO DRUG THERAPY CLINICAL TRIAL OF 90 PATIENTS AFFECTED BY JOINT-RELATED PAIN (TMJ) The mean VAS reduction of both the Laser group and the Drug group was almost equivalent and significant compared to the Placebo group. Published: CRANIO, April 2019 https://www.ncbi.nlm.nih.gov/pubmed/30999823

B-CURE LASER ’ S CLINICAL TRIALS B-Cure Laser ’ s efficacy for the treatment of pain and wounds has been proven in 5 double blind clinical trials. 5 other clinical trials are in process. For more details see Appendix 1 Joint-Related Pain (TMJ) Laminectomy Diabetic Wounds Dental Implantation Joint-Related Pain (TMJ) Sapienza University Sao Paulo Hospital Hadassah Medical Center PERM University University of Parma Italy Brazil Israel Russia Italy

B-CURE LASER BENEFITS PROVEN EFFICACY SAFE INNOVATION PROFIT STRONG IP For treating pain, For use by all family International The B-Cure laser Which surpasses orthopedic conditions, members of all ages, breakthrough, very large technology offers high competitors through inflammation, sports without the need for coherent laser beam potential profit for our advanced technology. injuries and wounds. protective goggles. with a treatment area of distributors and benefits Registered patents. 4.5cm 2. to our patients.

MORE THAN DEVICES SOLD (correct May 2020)

MARKET SURVEY Geocartography Knowledge Group Analysis by L. Gavish, Faculty of Medicine, The Hebrew University of Jerusalem, Israel SHOWS 60% of the patients who had suffered intolerable pain (8-10 NRS), SIGNIFICANT DECREASE experienced a significant pain decrease to bearable pain. IN INTOLERABLE PAIN Intolerable pain (Pain NRS = 8-10) A sample of 300 B-Cure Laser patients were n=177 randomly selected out of 76% 59% 10,000 n=69 B-Cure Laser patients, to participate in an independent market survey. Before treatment n=69 177 patients (59%) 70% considered themselves as suffering intolerable of the patients were satisfied with the device. pain. After treatment 69 patients (23%) Analysis by Dr. L. Gavish, The Hebrew University of considered themselves Jerusalem, Israel, August 2017, Israel as suffering intolerable pain.

RECOGNITION

PROFESSIONAL JUDO JUDO DE FEMME “ I can definitely say it was one WORLD CHAMPION NUMÉRO 1 MONDIAL of the best decisions I ’ ve made in my life. I used the device two-three times a day and within a few days the pain AGBEGNENOU CLARISSE decreased significantly . From AGBEGNENOU CLARISSE not being able to move my arm, I quickly managed to WOMEN JUDO WORLD CHAMPION make movements and return (2014, 2017, 2018, 2019) to training. B-Cure Laser Sport helped me return to routine faster than the “ usual recovery ” applying my standard care treatments. surprising even my doctors. I started training again very quickly. "

FOOTBALL JUDO DE FEMME “ A few months ago I heard about a device called UEFA CHAMPION NUMÉRO 1 MONDIAL B-Cure Laser Sport , which treats both the pain and the source of the problem with soft laser technology. What convinced me the most was that the device was tested here in Italy and STEFANO TACCONI AGBEGNENOU CLARISSE proved to be effective in a clinical trial. FORMER JUVENTUS GOALKEEPER No side effects, short treatment time, and I (1983-1992) could treat myself anywhere, at any time, at home and even while traveling . I began to treat myself with B-Cure Laser Sport and used it for the pains I had on both my legs and back. After several days of treatments at home I began to feel better - the pain decreased significantly and so did my mobility. I ’ m thrilled to recommend it to everyone, not only to professional athletes like me, but to anyone suffering from chronic pain, muscle aches, arthritis, orthopedic pain, and sport injuries . "