Dashboard Review End of FY 2015 Joe Selby, MD, MPH Executive - PowerPoint PPT Presentation

Dashboard Review End of FY 2015 Joe Selby, MD, MPH Executive Director Michele Orza, ScD Senior Advisor to the Executive Director

Discussion Questions • What is your view of our performance in FY 2015 and our status as of the end of FY 2015? • What are your thoughts about our funding commitments over the next four years ? • Is our approach to targeted topics optimal?

Legend *Influencing Research* On Target Q1=Q1 2015 A new graduate level Health Psychology course at Tulane University Board of Governors Off Target NA Q2=Q2 2015 is modeled on PCORI’s National Priorities for Research FY2015 Dashboard – Q4 Needs Attention Q3=Q3 2015 Our Goals: Increase Information, Speed Implementation, and Influence Research (As of 9/30/2015) Q4=Q4 2015 NA=Not Applicable Funds Committed to Research – up to $640M Projects Awarded Percent of Projects on Track Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Targeted 100 30 90 Pragmatic Number of Projects Percent Budget 80 Broad 70 20 60 Engagement 50 40 PCORNet Actual 30 10 20 10 NA NA 0 0 100 200 300 400 500 600 0 Research Engagement PPRNs CDRNs $ Millions Q1 Q2 Q3 Q4 Projects Completed as Expected Journal Articles Published Uptake of Methodology Standards 35 15 5,000 Q1 Q1 30 Expected Actual 30 Q2 Q2 Number of Projects 4,000 25 25 Q3 Q3 10 Number of Articles 20 3,000 Q4 20 Q4 15 15 2,000 5 10 10 1,000 5 5 0 0 0 0 Web Views Q1 Q2 Q3 Q4 By Awardees About or By PCORI Citations Expenditures – Total Budget, up to $362M Progress of PCORnet – Completion of Phase I Research Obesity Health Awards Systems Governance Cohort Budget Phase II policies Project Convening Research PFA Q1 Awards approved Event Awarded Released Actual Q2 All Other Q3 Budget Q4 Aspirin Phase II All Other Version 2.0 Q2 Q4 Q3 Q1 Actual Trial of CDM awarded 2015 2015 2015 2015 Awarded Complete 0 50 100 150 200 250 $ Millions

*Influencing Research* Goal 3 Results: A new graduate level Health Psychology course at Tulane University is modeled on PCORI’s National Priorities for Research PCORI Influence on Curriculum Michael Hoerger, PhD Assistant Professor of Psychology and Psychiatry Tulane University Designed a new Health Psychology course for the Masters Program in Behavioral Health based on PCORI’s National Priorities for Research • Course objective: prepare students for doctoral training in psychology so that they can ultimately pursue careers in clinical practice, research, and policy 10 modules, with 6 focused on PCORI • • Hoerger, M. (2015). Educating the Psychology Workforce in the Age of the Affordable Care Act: A Graduate C ourse Modeled After the Priorities of the Patient-Centered Outcomes Research Institute (PCORI). Training and Education in Professional Psychology. E-pub ahead of print. “PCORI’s five national priorities are noteworthy for psychologists and psychology trainees in terms of suggesting potential funding areas and clarifying trends in US healthcare for psychologists.”

We are making progress on our Strategic Priority to “ Increase the proportion of research funding going to focused and targeted topics” Funds Committed in Each Fiscal Year by Type of PFA FY 2014 FY 2013 FY 2015 Broad Total=$254M Total=$294M Total=$372M Pragmatic Targeted $78 $50 $58 $115 $196 $244 $179

And the result is a substantial shift in the distribution of our portfolio Funds Committed by Type of PFA, Cumulative Total by Fiscal Year End of FY 2015 End of FY 2014 End of FY 2013 Broad Total=$920M Total=$548M Total=$294M Pragmatic Targeted $186 $108 $50 $179 $555 $244 $440

Topic Prioritization Pathway LIST 1 To make list 1, Staff determine topic eligibility To make list 2, SOC reviews and endorses topics for topic briefs LIST 2 To make list 3, SOC reviews topic briefs and LIST 3 approves them for Advisory Panel review LIST 4 To make list 4, Advisory Panel reviews & prioritizes topics LIST To make list 5, SOC endorses topics for further refinement 5 To make lists 6&7, SOC assigns questions to Targeted or Pragmatic PFA LIST 7 LIST 6 Board reviews and SOC reviews and approves approves for questions for Pragmatic Targeted Targeted PFA Pragmatic PFA PFA PFA

Topic Prioritization Pathway: FY15 Q4 Snapshot Under Approved Funded Topics Consideration Topics Funded via Targeted PFAs For Targeted PFAs (List 6) SOC Endorsed for Refinement (List 5) • CAD-Aspirin Dose • Asthma • Chronic Pain/Long Term Opioid Therapy • Chronic Low Back Pain • Care Transitions • Multiple Sclerosis • Diabetes • NOACs for blood clots • Falls in Elderly Mental Health Integration • • Treatment-Resistant Depression • Hepatitis C- New Therapies • Palliative Care • Sickle Cell Disease • Hypertension For Pragmatic Studies PFAs (List 7) Reviewed by Advisory Panels (List 4) • Obesity in Diverse Populations • Autism Spectrum Disorders- • Antimicrobial Resistance • Severe Asthma in African behavioral analysis • Autism Spectrum Disorders- risk assessment Americans & Hispanics • Cardiovascular Disease • NOACs for stroke prevention • Uterine Fibroids • Caregiver Engagement & Support • Care coordination • Carotid Artery Disease • Cognitive Impairment • Communication • Dental Caries Funded via Pragmatic PFAs Coronary Artery Disease- Statins • • Diabetes • Bipolar Disorder • Dementia • End Stage Renal Disease • Breast Ductal Carcinoma in Situ • Genetic Testing for Rare Disease • Insurance Design • Glaucoma • Crohn’s Disease- Biologics • Medication Management • Health IT & Evidence-Based Treatment • Chronic Back Pain • Migraine • High Cholesterol • Musculoskeletal Pain • Hip Fractures • Implantable Cardiac Defibrillators • Opioid Abuse Treatment • Mental Health & Primary Care • Links btw Providers & Community • Osteoarthritis • Neck Pain • Particle Beam Therapy • Pelvic Floor Dysfunction • Orthopedic Surgery • Pulmonary Nodules & CT • Pneumonia • Pre-term & Low Birth Weight Surveillance • Post-Acute Care Transitions • Suicide Prevention • Role of Spacers in Asthma • Tobacco Use Prevention & Cessation • Substance Abuse- Adolescents/Alcohol • Traumatic Brain Injury • Weight Maintenance & Reduction

We have projects focusing on a wide range of conditions, with the largest concentrations in mental/behavior health and cancer Funded Projects by Primary Disease/Condition (N=283) - Cycle I through Spring 2015 Mental/Behavioral Health 43 Cancer 40 Cardiovascular Health 26 Cross-cutting 22 Rare Diseases 21 Nutritional and Metabolic Disorders 20 Neurological Disorders 19 Respiratory Diseases 17 Multiple/co-morbid chronic conditions 16 Reproductive and Perinatal Health 12 Trauma/Injury 12 Muscular and Skeletal Disorders 11 Infectious Diseases 10 Kidney Disease 8 Digestive System Diseases 3 Allergies and Immune Disorders 2 Skin Diseases 1 0 10 20 30 40 50 *Categories are mutually exclusive *Does not include Methods projects

The majority of studies in our portfolio are clinical trials Funded Portfolio by Study Design Cycle I through Spring 2015 Study Design by Study Design by Number of Awards Award Amount ($) (N=283) Total: $838M $168 M 26% 20% $37 M 4% $634 M 7% 76% 67% Randomized Controlled Trials Secondary Data Analysis Observational (Prospective) *Does not include Methods projects

The majority of our studies focus on treatment and 18% of our funding is in screening and prevention studies Funded Portfolio by Care Continuum Cycle 1 through Spring 2015 Care Continuum by Care Continuum by Proportion of Projects Proportion of Funding N=283 Total: $838M 4% 3% 3% 4% 2% 2% 10% 14% 77% 82% Treatment Prevention Screening Diagnosis Other *Does not include Methods Projects

The majority of our research funding has gone to our APTDO and IHS portfolios Total= 355 Projects, $920M AD 18% APDTO Methods 41% 8% CDR 7% IHS 26%

We actively monitor our projects, support them to be successful, and classify their progress as shown below -AND- -AND- -AND- -OR- -OR- -OR- -OR- -OR- -OR- The “Percent of Projects on Track” shown on the Dashboard is the percent of projects in the green zone

The majority of our projects are on track and we are giving additional attention to those that are not Distribution of Project Status by Quarter Q4 2015 13 183 67 11 1 Q3 2015 180 54 9 14 1 Green Zone Yellow Zone Orange Zone Q2 2015 130 47 16 11 Red Zone Award Terminated* 0 25 50 75 100 125 150 175 200 225 250 275 300 Number of Projects *Notice of Termination Issued

Some projects require contract modifications in order to be successfully completed Reasons for Contract Modifications 40 Percent of total projects by Q of FY15 35 Number (N) of total projects differs by Q 30 Q1 (N=195) Q2 (N=222) Q3 (N=259) Q4 (N=278) 25 % 20 15 12 10 8 8 7 6 5 5 4 5 3 2 2 2 2 0 0 0 0 Milestones Scope of Work Period of Performance Budget (Increase) • Includes all research projects with at least one progress report due • Does not include infrastructure or pilot projects