Cryolipolysis, RadioCavitation, Multipolar RF and Lipomassage Biotec - - PowerPoint PPT Presentation

Cryolipolysis, RadioCavitation, Multipolar RF and Lipomassage

• Established in 1993
• Manufacturing and distributing machines, cosmeceuticals to aestheticians

and doctors in over 50 Countries

• Cooperating with research centers, universities and pharmaceutical

companies in Italy and UK

• 2 product lines Renlive and Rejuve , mesotherapic cocktails, hyaluronic acid

fillers and a number of machines for aesthetic and medical use.

• Machines for aesthetic use are all CE marked
• Machines for medical use have a medical CE
• Medical ISO 13485 standards

Biotec Italia: enhancing people skin since 1993

 We DO NOT sell machines  We sell PLATFORMS  Combined technologies in one single unit  Better results  Save money space!

State of the art technology

Complete aesthetic solution For facial and body procedures

CoaxMed offers the most advanced body and facial procedures by Integrated Intelligent technology. The modular system provides 4 major technologies Cryolipolysis, Radiocavitation, Multi-polar RF and Lipomassage,to complete effective non-invasive facial and body procedures.

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Cryolipolysis Radiocavitaion Multipolar RF Lipomassage

Convenient User Interface

[ Face Contour MODE ]

[ Choose treatment by skin condition or by procedure ]

[ CoolShape MODE ] [ Lipomassage MODE ]

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Handpieces

CoolShape

Cryo + Vacuum, + Radiofrequency

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RF Shape Face

Mono + Bipolar RF + Vacuum + Cryo

DuoShape

Radiofrequency + Cavitation

3-Polar RF

Multipolar Rf + Vacuum + Cryo

Skin Tite

Fractional Needles RF + Vacuum

What is Cryolipolysis?

Cryolipolysis refers to a novel non-invasive technology using cold exposure to selectively and gradually lead to the reduction of subcutaneous fat. When fat cells are exposed to precise cooling, they trigger a process

• f natural removal that gradually reduces the thickness of the fat layer.

The fat cells in the treated area are gradually eliminatedthrough the normal metabolic process of unwanted fat elimination.

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How Cryolipolysis works?

Step 1. Emit heat-cool energy to target. fat area Step 2. T arget fat area with maintaining cool-energy extraction rate. Step 3. Fat cells reach a biological death slowly. Step 4. The fatty cells in the treated area are eliminated through the body’s natural metabolism process.

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How CoolShape handpiece works?

The fat cells in the target area begin responding to cryo-crystallization. Apply Coolshape applicator at the target area, Start treatment to reach a target temperature. The fat cells are eliminated. Following the treatment, fat cells reach an biological death and removed by metabolism process.

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• STEP3. 30 days

Metabolism process

• STEP4. 90 days

Eliminated cells

• STEP1. Start

Heat-Cryo energy

• STEP2. Immediate

Cryo-reaction

CoolShape

Integrated T echnology by Cryo, V acuum and RF

• E n d

P o i n t :

Lipolysis

Powerful Cryolipolysis system

• Fouror eight powerful cooling elements fitted in to the

handpiece.

• Automatically control the cooling temperature.
• maximum -10 °C

V ariable vacuum function

• Controllable vacuum level : step 10(low) to step 60(high)

Bipolar Radiofrequency

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Vacuum

RF

CoolShape

 Handpiece layout

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247mm 148mm

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Clinical Method

Clinical evaluation of the patient;  Selection of the area to be treated (dermographic pen);  A protective membrane is placed on the skin;  The area to be treated is sucked into the handpiece;  The treatment starts with the preheat cycle and then the area is gradually brought to - 10°C and a cycle of 60 minutes begins

Skin after treatment Skin before treatment

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CoolShape TreatedAreas by

26% 35% 7% 10% 4% 10% 5% 3% 0% 10% 20% 30% 40% A b d

• m

e n

• F

l a n k s

• B

a c k

• T

r u n k

• T

h i g h s / k n e e s

• A

r m s

• B

u

• c

k

• B

r e a s t

• Love Handles

Male patients with pseudo gynecomastia asked for a treatment in the breast area

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CoolShape Ultrasound Results by Fat layer evaluation

 An ultrasaund device has been used to assess the thickness of the fat layer before the treatment and after 30 and 60 days  Picture of the treated area before the treatment and after 30 and 60 days

Courtesy of Ciro Borriello MD

( F / 31, Abdomen, 2 session with 4 weeks interval)

0.92 cm 2.06 cm May 20, 2013 14:55:09 July 30, 2013 17:55:20

before treatment 8 weeks after treatment

( 4weeks after second treatment )

Note the 1.14cm change in subcutaneous fat thickness

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CoolShape Ultrasound Results by

0.99 cm 2.16 cm March 08, 2013 10:45:33 May 22, 2013 16:45:22

before treatment 8 weeks after treatment

( 4weeks after second treatment )

Note the 1.17 cm change in subcutaneous fat thickness

9 ( F / 39, Abdomen, 2 session with 4 weeks interval)

CoolShape Ultrasound Results by

CoolShape Ultrasound Results by

0.88 cm 1.52 cm Sep 08, 2013 11:25:20 Nov 30, 2013 15:30:35

before treatment 8 weeks after treatment

( 4weeks after second treatment )

Note the 0.64cm change in subcutaneous fat thickness

10 ( M / 26, Abdomen, 2 session with 4 weeks interval)

This delivered

before treatment 6 weeks after treatment

( 2weeks after second treatment ) 8

CoolShape Clinical Results by

Patient M.A.

Female, 27 years

before treatment 6 weeks after treatment

( 2weeks after second treatment ) 8

CoolShape Clinical Results by

Patient F.M.

Male, 21 years

before treatment 6 weeks after treatment

( 2weeks after second treatment ) 8

CoolShape Clinical Results by

Patient G.C.

Male, 25 years

before treatment 8 weeks after treatment

( 4weeks after second treatment ) 8

CoolShape Clinical Results by

Patient R.C.

Female, 35 years

before treatment

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CoolShape Histological Analysis by

During our experience, we performed some treatments on surgical patients

• ne month before an abdominoplasty

after surgery, the fat excess piece removed was submitted to a private lab for histological analysis. Histological sections were stained with hematoxylin and eosin and evaluated microscopically to assess the level of fat damage and any damage to the dermis or epidermis. The analysis showed a widespread phagocitosys of fat cells by macrophages

CoolShape

 Delivers optimized heat-cool energy for local reduction of fat cells a n d reshape body contours.  The exposure to cooling causes fat cell death without damage to other tissue area or skin surface.  Maintain the stable target temperature during treatment. Additionally V acuum and RF cycle effectively enhance the treatment result and skin elasticity.  The fatty cells in the treated area areeliminated through the body’s natural metabolic process.  Fatty layer reduction show persistent results at least 6~8months after the treatment.

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Duoshape Performance (Cavitation + Radiofrequancy)

Cavitation Effect

[Data: Nature, 2005]

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DuoShape (capacitative monopolar radiofrequency + Low Frequency Ultrasoung), has the aim of producing heat and activating the heat shock proteins and to generate nonthermal selective focused ultrasound to produce localized mechanical motion within fats tissues and cells for the purpose of producing mechanical cellular membrane disruption. Low Frequency Ultrasoung aims also to sonophoresis mesotherapy which allows specific substances to penetrate the cell cytoplasm in order to activate the metabolism of fats in any area of the body where there is an accumulation of fat and in all types of tissues, including those that display signs of flaccidity.

Cavitation Performance

MONITORING WITH ELECTRONIC MICROSCOPE OF CA VIT A TION

Before Cavitation 2 min. later 5 min. later 10 min. later

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• Cavitation consists in the formation of gas bubbles in a liquid
• Bubbles form during a negative pressure phase
• They get bigger and bigger during this phase
• The great pressure exerted on the just expanded bubble, compress the bubble, thus leading to a

great increase on the gas temperature in them contained

DuoShape

Enhances deep fat removal effect

• Fat reduction

 Powerful Ultra-cavitation performance  Effective 28 KHz Ultrasound frequency  Effective Monopolar Radiofrequency 600 Khz  Water cooling for ultrasound stable emission

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3-Polar RFPerformance

3-Polar RF technology painlessly delivers focused and

• ptimal RF energy to the skin surface and to subcutaneous fat

layers. Controlled energy is delivered via 3 electrodes, centered between them, and limited only to the treatment area. This delivered RF energy that improves result in the treated focal area.

3-Polar RFT reatment Process

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Vacuum suction can be combined to optimized RF delivery

3-Polar Shape

3-Polar RF thermal energy

• Tightening, Lymph drainage

 Multi-polar RF Thermal energy  Applied temperature sensor technology  Synergetic combination of multi-polar RF, Cryo and Vacuum suction  Maximize the effect by optimum RF frequency  Stimulate blood circulation  Effect of skin tightening and lymph drainage

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Lipomassage

• Tightening, Lymph drainage

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CRYO VACUUMLIPOLYSIS (Cryo + Radiofrequency + vacuum)  Amount of extracellular water is increased significantly  Increase in temperature necessary to stimolate the heat shock proteins (responsible for the contraction of collagen)  Produce a deep heat that helps the lymphatic drainage, which reduces the liquids and toxins found in tissue affected by cellulite  Produce cryo effect on the tip in contact with the skin, in order to protect the epidermis and allowing an higher scale of radiofrequency intensity, when compared to RF emission in absence of tip cooling.

Additionally, it produces an increase in the circulation of the area which will improve the metabolism of the fatty subcutaneous tissue as well as improving the appearance of the

• verlying skin, enhancing the results of the procedure.

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The 300 KHz-1 MHz monopolar radiofrequency is capable of generating an electric field that switches from positive to negative, creating a rotational movement of the water molecules that produces heat. This produces a deep heat that spreads from the inside outwards. This heat triggers different active mechanisms: 1.Thermal effect that produces:

• vasodilatation
• anti-inflammatory and antalgic effect
• increased tissue oxygenation
• muscle relaxation effect
• 2. Heat Shock Proteins are released (HSP)

The HSP that are synthetised in certain situations of stress give rise to the start of tissue repair. In particular with Radiofrequency HSP-47* is formed which is a protein that recognises the collagen triple helix.

FACE MONOPOLAR AND BIPOLAR RADIOFREQUENCY WITH VACUUM AND CRYO

Skin Tite

Microneedling RF + Vacuum

• Deep

SkinTightening

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 The handpiece tip is positioned on the epidermis and vacuum is used to fold the skin.  Microneedles penetrate into skin (Penetration depth is adjustable according to needle’s length.)  Microfractional holes are created in epidermis and dermis.  Monopolar radiofrequency is emitted in deep dermis inducing dermal coagulation.  Microneedles are withdrawn and new micro-holes are generated, granting a fast coverage of the treated area.

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MARIONETTE LINES IMPROVEMENT Before After 3 session

40% 25% 35% 25-50% 50-75% 75-100%

Clinical Study carried out on 20 subjects

Before After 3 session

8% 44% 28% 20% 0-25% 25-50% 50-75% 75-100%

NASOLABIAL FOLD IMPROVEMENT

Clinical Study carried out on 25 subjects

Skin Tite Clinical Results by

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Acne Scarring

Skin Tite Clinical Results by

before treatment after 6 treatment

( 1weeks after treatment )

CoaxMed Advantages

 Unique Multi-Functional System

• Combination of cryolipolysis, Cavitation,Vacuum and multi-polar RF

 Absolute treatment results via combination treatment

• Integrated using of 5 different hand-pieces technology bring optimal outcome of fat

reduction and body and face rejuvination.

• Works to: Lipolysis, Fat reduction, Cellulite, S k i n Tightening, Lymph drainage

 Deliver a stable Cool-energy & Comfortable treatment

• Coolshape with i n s u l a t e d Peltier technology

 Can operate two main technologies at once

• CooloShape Duoshape, Lipomassage handpieces

 Non-Invasive & Safe procedure

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