Compression Applicator and HDR 192 Ir Mark J Rivard, PhD, 1 Raymond J - - PowerPoint PPT Presentation

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Mark J Rivard, PhD,1 Raymond J Bricault Jr., MSc,2 Christopher S Melhus, MSc,1 Jessica R Hiatt, MSc,3 Piran Sioshansi, PhD,2 and David E Wazer, MD,1,3

1 Tufts-New England Medical Center, Boston, MA 2 Advanced Radiation Therapy, LLC, Billerica, MA

3 Rhode Island Hospital, Providence, RI

Stereotactic Breast Brachytherapy Applied Peripherally Using a Compression Applicator and HDR 192Ir

Full Disclosure

Rivard & Wazer are medical advisors to ART Bricault & Sioshansi are officers of ART AccuBoost is FDA approved only for breast brachytherapy

Treatment Process Overview

AccuBoost System: Equipment Integration

mammography unit W-collimated applicators computed radiography

system

Stereotactic Brachytherapy Image Guidance

before alignment after alignment

Applicator: Mammography Paddle Interface

compression paddle applicator alignment

AccuBoost Applicator Schematic

AccuBoost Irradiation Beam

Ionization Chamber & Film Measurements

Central Plane Dose: 5 cm Applicator

Central Plane Dose: 6 cm Applicator

Central Plane Dose: 7 cm Applicator

Depth Dose Profile: 6 cm Applicator

Monte Carlo Simulation Geometry

cross-sectional view planar view through HDR dwells

Calculated AccuBoost Dose Profiles

Calculated Skin / Center Dose Ratio

Dosimetric Comparison

Summary

• AccuBoost system integrates

– mammography – computed radiography – externally-collimated HDR 192Ir source

for stereotactic breast brachytherapy

• measured & simulated dosimetry: good agreement
• forthcoming multi-institutional clinical use