Collaboration Renal MRI Creating room and momentum through - PowerPoint PPT Presentation

Collaboration Renal MRI “Creating room and momentum through facilitation” Registered charity no. 252892. Scottish charity no. SC039245.

Patient survey on research priorities Weighted Score for research priorities 0 1000 2000 3000 4000 5000 6000 7000 8000 2,200 responses Cures for kidney disease All stages of disease pathway Prevention of kidney disease represented Finding new sources of organ transplants Third survey Early detection of kidney diseases undertaken by the Improving treatments to make damaged charity kidneys last longer Improving methods of transplantation Stem cell research Registered charity no. 252892. Scottish charity no. SC039245.

UK Renal Research Strategy Launched 14 th April 2016 Patients Collaboration Balanced UKRRS Steering Group Registered charity no. 252892. Scottish charity no. SC039245.

Registered charity no. 252892. Scottish charity no. SC039245.

Some Partnership Challenges… Blockbuster costs; average cost to Innovation ? Making a bring an asset from discovery to difference market : > $1.5 billion ? Hope? Regulatory hurdles Operational environment challenges Measuring the return from pharmaceutical innovation – 2016 (7 th Annual Report) Registered charity no. 252892. Scottish charity no. SC039245.

New Collaborative Opportunities Registered charity no. 252892. Scottish charity no. SC039245.

Registered charity no. 252892. Scottish charity no. SC039245.

Value Appreciation: 9 Target engagement Disease Biomarkers Progression Biomarkers The lack of predictive biomarkers of disease progression is currently the largest single obstacle for the development of treatments for CKD” Disease progression Biomarker = Something that will tell us whether CKD is in a stable (ie. losing <2ml/min/yr GFR, progressive (2-5 ml/min/yr) or rapidly progressive (> 5ml/min/yr GFR) state in a spot sample

UK Renal Imaging Network UK Regenerative UK Fibrosis - Network Medicine Network

Iron and Muscle Assessing the impact of IV iron therapy on exercise & physical capacity in CKD patients

Creative Imagination Registered charity no. 252892. Scottish charity no. SC039245.

• Facilitation - bridging • Governance • Communications to support publication activity • PPI • Share learnings and best practice Equitable – open and objective partnerships Sustainability Impact Registered charity no. 252892. Scottish charity no. SC039245.