Christo Christov Christo Z. . Christov MICHIGAN TECH RESEARCH - - PowerPoint PPT Presentation

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Christo Christov Christo Z. . Christov MICHIGAN TECH RESEARCH - - PowerPoint PPT Presentation

MICHIGAN TECH RESEARCH FORUM TECHTALKS Christo Christov Christo Z. . Christov MICHIGAN TECH RESEARCH FORUM christov@mtu.edu TECHTALKS Research / Scholarship Computational Biochemistry Reaction Mechanisms of Enzymes Dynamics of


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SLIDE 1

MICHIGAN TECH RESEARCH FORUM

TECHTALKS

Christo Christov

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SLIDE 2

Research / Scholarship

  • Computational Biochemistry
  • Reaction Mechanisms of Enzymes
  • Dynamics of Enzyme Substrate

Complexes

  • Computational Design of Enzymes

and Proteins

MICHIGAN TECH RESEARCH FORUM

TECHTALKS

Christo Z. . Christov

christov@mtu.edu

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SLIDE 3

Scholarly Contributions

  • Histone Demethylation by Fe-containing Enzymes

NAME, e-mail address

Christo Z. Christov

christov@mtu.edu

H3K9me2 H319 H247 D249 2OG Fe2+ H3K9me2 H319 H247 D249 2OG Fe2+ A B

3.1Å Fe-O 2.0Å 4.12

  • 0.46
  • 0.25

H3K9me2- CH3 2.4 Å H319 H247 D24 9 Fe3

+