Applications of the Classical Model Abigail Colson Antibiotic - - PowerPoint PPT Presentation

applications of the classical model
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Applications of the Classical Model Abigail Colson Antibiotic - - PowerPoint PPT Presentation

Applications of the Classical Model Abigail Colson Antibiotic resistant bacteria by Microra is licensed under CC BY-SA 4.0 "Fun with Insects" by Pioneer Library System is licensed under CC BY-NC-ND 2.0 "Chicago


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Applications of the Classical Model

Abigail Colson

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"Fun with Insects" by Pioneer Library System is licensed under CC BY-NC-ND 2.0 "Chicago Floods-31" by Jpos is licensed under CC BY-NC 2.0 “Antibiotic resistant bacteria” by Microra is licensed under CC BY-SA 4.0

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“A model wearing disponsable medical PPE” by Timely Medical staff is licensed under CC BY-SA 2.5 "antibiotic discs" by Iqbal Osman1 is licensed under CC BY 2.0

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Variables of interest

Bug/drug pairs

1.

  • E. coli and fluoroquinolones

2.

  • E. coli and cephalosporins

3.

  • E. coli and carbapenems

4.

  • K. pneumoniae and cephalosporins

5.

  • K. pneumoniae and carbapenems

6.

  • S. aureus and methicillin

7.

  • S. pneumoniae and penicillins

8.

  • N. gonorrhoeae and cephalosporins

9.

  • P. aeruginosa and any treatment

Countries

1. France 2. Italy 3. Spain 4. United Kingdom

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The Surveillance Atlas of Infectious Disease is available for use from the ECDC.

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  • E. coli resistance to carbapenems

Data from https://doi.org/10.1371/journal.pone.0219190

Red line: historical data from EARS-Net Dashed line: median assessments Light grey: 90% credible range Dark grey: 50% credible range Experts provided assessments for 2018, 2021, and 2026.

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Klebsiella resistance to carbapenems

Data from https://doi.org/10.1371/journal.pone.0219190

Red line: historical data from EARS-Net Dashed line: median assessments Light grey: 90% credible range Dark grey: 50% credible range Experts provided assessments for 2018, 2021, and 2026.

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Comparing experts and models

Figure by Colson et al. is from https://doi.org/10.1371/journal.pone.0219190 and licensed under CC BY 4.0

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Photos of two infants in an advert for Mellin's food from Wellcome Images is licensed under CC-BY-4.0

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Variables of interest

Feeding Feeding Patterns by Age Cohorts 1 2 3 4 Breastfeeding, Exclusive None 3 months 6 months 6 months Breastfeeding, Any None 3 to 9 months None 6 to 24 months Infant Formula, Exclusive 6 months None None None Infant Formula, Any 6 to 15 months 3 to 15 months 6 to 15 months None Complementary Foods From 6 months From 6 months From 6 months From 6 months

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"Stormwater in Annapolis, Md." by chesbayprogram is licensed under CC BY-NC 2.0

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References

Colson, A. R., et al.. (2019). Quantifying uncertainty about future antimicrobial resistance: Comparing structured expert judgment and statistical forecasting

  • methods. PLOS ONE, 14(7), e0219190.

https://doi.org/10.1371/journal.pone.0219190 Colson, A. R., Cooke, R. M., & Lutter, R. (2016). How Does Breastfeeding Affect IQ? Applying the Classical Model of Structured Expert Judgment. Retrieved from Resources for the Future website: http://www.rff.org/research/publications/how- does-breastfeeding-affect-iq-applying-classical-model-structured-expert Koch, B. J., et al. (2015). Suburban watershed nitrogen retention: Estimating the effectiveness of stormwater management structures. Elementa: Science of the Anthropocene, 3, 000063. https://doi.org/10.12952/journal.elementa.000063

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Thank you for your attention!