antimalarials and RDTs: an update on ACTwatch Stephen Poyer, Deputy - - PowerPoint PPT Presentation

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antimalarials and RDTs: an update on ACTwatch Stephen Poyer, Deputy - - PowerPoint PPT Presentation

Jan 08, 2024 266 likes •436 views

Monitoring supply and demand for antimalarials and RDTs: an update on ACTwatch Stephen Poyer, Deputy PI, ACTwatch on behalf of the ACTwatch Group What is ACTwatch ? Nigeria Cambodia Benin Uganda Myanmar Kenya DRC 10-country project

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Monitoring supply and demand for antimalarials and RDTs: an update on ACTwatch

Stephen Poyer, Deputy PI, ACTwatch

  • n behalf of the ACTwatch Group
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www.ACTwatch.info 2

Madagascar Benin Cambodia DRC Uganda Zambia Kenya Tanzania Zanzibar Myanmar Nigeria

What is ACTwatch?

Objective

Provide policy makers with evidence

  • n trends in availability, price,

market share and use of antimalarials and diagnostics

Partnership

PSI, LSHTM and MoHs

10-country project

Funded by the BMGF 2008-2013, and BMGF, DfID, and UNITAID from 2013-2015

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3 www.ACTwatch.info

Research Methods: Outlet Surveys

  • Clusters randomly selected proportional to population size;
  • Census of all outlets with the potential to stock antimalarials;
  • Over-sampling of public health facilities and pharmacies;
  • Audit of all antimalarials in stock:
  • generic name - brand name – manufacturer - formulation – strength –

expiry date – price - volume (quantity) sold/dispensed in the last 7 days;

  • Additional focus on diagnostic testing (RDT/microscopy);
  • Data are survey set to account for clustering and weighted to

provide nationally representative estimates.

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  • Benin
  • Martine-Esther Tassiba
  • Cyprien Zinsou
  • Ghyslain Guedegbe
  • Aristide Hontonou
  • DRC
  • Dr Louis Akulayi Tshisungu
  • Dr Godé Mpanya
  • Willy Mpwate
  • Madagascar
  • Iarimalanto Rabary
  • Jacky Raharinjatovo
  • Justin Rahariniaina
  • Sitraka Ramamonjisoa

4 www.ACTwatch.info 11/12/2013

Internal capacity building: Local research teams

  • Nigeria
  • Ekundayo D. Arogundade
  • Chinazo Ujuju
  • Uganda
  • Peter Buyungo
  • Simon Sensalire
  • Henry Kaula
  • Zambia
  • Nicholas Shiliya
  • Felton Mpasela
  • Edward Ngoma
  • Cambodia
  • Sochea Phok
  • Phou Mean
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5 www.ACTwatch.info 11/12/2013

Internal capacity building: PSI research process

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6 www.ACTwatch.info 11/12/2013

Internal capacity building: PSI research process

Myanmar: Artemisinin Monotherapy Replacement Project

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www.ACTwatch.info 7 Rural pharmacy depot, Madagascar, 2009

Results: Availability

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Availability of QAACTs among private for-profit outlets stocking antimalarials, 2009 and 2011

8 www.ACTwatch.info 11/12/2013

Trends in availability of quality-assured ACTs in the private sector

6 8 27 11 16 23 9 51 66 20 10 20 30 40 50 60 70 80 90 100 N=632/914 N=1854/1632 N=1831/1379 N=1575/2331 N=258/490 Benin Madagascar Nigeria Uganda Zambia Percentage of outlets 2009/2010 2011

2009/2010 & 2011 Outlet Survey Results

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9 www.ACTwatch.info 11/12/2013

69 4 95 92 18 25 58 11 77 52 93 10 20 30 40 50 60 70 80 90 100 2011 Benin 2009 DRC 2011 Madagascar 2011 Nigeria 2011 Uganda 2011 Zambia Percentage of outlets Chloroquine SP

Availability of non-artemisinin therapies among private for-profit outlets stocking antimalarials, 2011

Private sector availability of CQ, quinine, and SP

2011 Outlet Survey Results

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Results: Market share

Informal outlet, DRC, 2010

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0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 2011 2009 2011 2011 2011 2011 Benin DRC Madagascar Nigeria Uganda Zambia QAACT non-QAACT non-artemisinin therapy non-oral artemisinin monotherapy

  • ral artemisinin monotherapy

11 www.ACTwatch.info 2011 Outlet Survey Results

Private-for-profit sector antimalarial market share

30% CQ 34% SP 60% CQ 25% AQ 35% SP 20% QN 26% CQ 42% SP 26% SP 71% SP

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Pharmacy in rural DRC, 2010

Results: Price

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$5.87 $0.14 $4.47 $2.79 $11.01 $2.00 $0.60 $1.48 $1.96 $4.87 0.00 1.00 2.00 3.00 4.00 5.00 6.00 7.00 8.00 9.00 10.00 11.00 12.00 13.00 Benin n=353; n=854 Madagascar n=380; n=1057 Nigeria n=1001; n=1894 Uganda n=583; n=3291 Zambia n=89; n=253 Price, 2010 $USD 2009 / 2010 2011

13 www.ACTwatch.info 2009/2010 & 2011 Outlet Survey Results

Median price of one adult equivalent tablet dose of QAACT (tablet) in the private sector, 2009 and 2011

Private sector quality-assured ACT price trends

n = number of antimalarials

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  • A comprehensive picture of the antimalarial market in

the focus country

  • A comprehensive picture of the malaria diagnostic

market in the focus country

  • Trends in antimalarial availability and pricing
  • Provider practices regarding prescribing antimalarial

medicines

  • Raw data for academics for additional analysis that will

inform the NMCPs

www.ACTwatch.info 14

External capacity building: Publicly-available data to support partner’s research programmes

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www.ACTwatch.info 15

“Knowing is half the battle” – use the information to address access to quality-assured ACTs in your country

www.ACTwatch.info

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