Alfred O.C. Nier 1911-1994 Electron Impact (Nier-type) Thermal - - PowerPoint PPT Presentation

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Nov 25, 2022 166 likes •323 views

Alfred O.C. Nier 1911-1994 Electron Impact (Nier-type) Thermal Ionization Plasma Ion Source Microwave Plasma source Secondary Ionization Sputter Ionization Source Matrix-assisted Laser Desorption and Ionization (MALDI) Electrospray

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Alfred O.C. Nier 1911-1994

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Electron Impact (Nier-type)

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Thermal Ionization

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Plasma Ion Source

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Microwave Plasma source

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Secondary Ionization

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Sputter Ionization Source

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Matrix-assisted Laser Desorption and Ionization (MALDI)

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Electrospray Ionization

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Relative pros and cons of different ionization techniques

Ionization type Efficiency Selectivity Fragmentation Stability Electron impact + + + + Thermal ionization +

RF Plasma

Sputter

+++ ++ +

MALDI

Electrospray

Resonant

photoionization +++

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Electron Energy

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Open versus Tight sources

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Pushing versus Pulling

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