Adherence, Hypertension, Claims data, EventFlow & CoCo Margrt - - PDF document

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May 30, 2023 228 likes •367 views

6/2/2016 Adherence, Hypertension, Claims data, EventFlow & CoCo Margrt Vilborg Bjarnadttir Robert H. Smith School of Business | University of Maryland With Sana Malik & Catherine Plaisant & Eberechukwu Onukwugha Adherence

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Adherence, Hypertension, Claims data, EventFlow & CoCo

Margrét Vilborg Bjarnadóttir Robert H. Smith School of Business | University of Maryland

With Sana Malik & Catherine Plaisant & Eberechukwu Onukwugha

Adherence

Morbidity
Mortality
Costs

– $13.35 billion in hospitalization costs annually due to medication non-adherence (Sullivan et al 1990)

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The medication possession ratio (MPR):

period n

bservatio
f

length supplied days



time Study start Study end

= 83%

Adherence Measurement

900,000 Individuals
16 million prescription claims
5 Drug classes:

– Angiotension-Converting Enzyme-Inhibitors (ACE) – Angiotension II Receptor Blockers (ARB) – Calcium Channel Blockers (CCB) – Beta blockers (Beta) – Diuretics

The Data

Michael A. Kane, Margrét V. Bjarnadóttir, Sanjay Ghimire. 2012. “Study of compliance in hypertension treatment” American Society of Hypertension, Annual Scientific Meeting. Poster Presentation, New York, NY, May 2012.

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Can we use visualization to understand

adherence patterns

– Can we derive new metrics/visualizations/knowledge – Can we make better prescription decisions

The Research Questions

time

Hypertension Treatment

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time

Hypertension Treatment

time

Hypertension Treatment

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Can we use visualization to understand

adherence patterns

– Can we derive new metrics/visualizations/knowledge – Can we make better prescription decisions

What are the effects of our modeling

decisions

Can we understand different subgroups better

The Research Questions

time

Hypertension Treatment

time

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Gaps & Overlaps Gaps & Overlaps

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PATTERNS AND MODELING DECISIONS

Case study

Event Flow

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General Patterns Modeling Decisions* Diuretics Only - Gaps

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Diuretics Only - Gaps Drilling Down with CoCo

Adherent vs. non-adherent
Ace-Inhibitors vs Diuretics

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Summary

All of the standard data cleaning

considerations apply and are necessary

CoCo can quickly compare two cohorts and

give an overall feel the differences between the two groups

margret@rhsmith.umd.edu