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Academic Health Science Centres engines of innovation or re-inventing the wheel? The challenges confronting the UK healthcare system: Improving service quality while reducing costs Redesign of patient pathways Shifting emphasis


  1. Academic Health Science Centres – engines of innovation or re-inventing the wheel?

  2. The challenges confronting the UK healthcare system: • Improving service quality while reducing costs • Redesign of patient pathways • Shifting emphasis from treatment to prevention • Accelerating the translation of discovery into patient benefit

  3. Universities and their hospital partners risk being driven apart by: • the target and management culture of the NHS • the RAE’s emphasis on basic science • imminent financial pressures

  4. Universities and their hospital partners risk being driven apart by: • the target and management culture of the NHS • the RAE’s emphasis on basic science • imminent financial pressures

  5. An Academic Health Sciences Centre at the heart of a world city Professor Robert Lechler

  6. The partners – four highly-performing institutions Page 5 Page 5 Guy’s and St. Thomas’ Enfield Barnet Harrow Haringey Waltham Redbridge Forest Havering Brent Islington Hillingdon Hackney Camden Barking Newham Tower Westminster Hamlets Ealing City Ken. & Chel . Southwark Hounslow Greenwich Lambeth Bexley Wandsworth Richmond Lewisham South London and the Maudsley Merton King’s College Hospital Bromley Kingston Croydon Sutton

  7. Our vision – a radical change in healthcare Page 6 Page 6 King’s Health Partners is pioneering better health and well-being, locally and globally, through integrating excellence… in research in education/training in patient care

  8. The vision – a radical change in healthcare Page 7 To advance health and well-being by integrating world-class research, care, education and training through: • Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training • Integrating physical and mental healthcare to deliver a holistic approach to patient care • Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention • Developing a workforce that will transform healthcare – delivering innovation through education

  9. The vision – a radical change in healthcare Page 8 To advance health and well-being by integrating world-class research, care, education and training through: • Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training • Integrating physical and mental healthcare to deliver a holistic approach to patient care • Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention • Developing a workforce that will transform healthcare – delivering innovation through education

  10. Clinical Academic Groups: key to accelerating translation Page 9 KCL GSTT KCH SLaM Partnership Board King’s Health Partners Executive Drive basic Basic Sciences discovery Institute NIHR Biomedical Drive translation Research Centres Dementia and Diabetes Other Clinical Cardiovascular Older People’s and Academic Mental Health Obesity Groups Health Policy and Evaluation Evaluate Institute Efficient infrastructure to Infrastructure to support CLINICAL ACADEMIC GROUPS deliver translation Experimental medicine Disorder- / Research-based training Disseminate knowledge, Disorder / Research EDUCATION ACADEMY train the next generation Based Training and Education and education

  11. CAG and Research Group Structure Page 10 Page 10 Basic Science Institute 5. Cancer, 1. Liver, Renal, 2. Orthopaedics, 3. Cardio- 4. Clinical Haematology, Urology,Transplant Trauma, ENT & 6. Dental Vascular Neurosciences Palliative Care & Gastro/GI Surgery plastics & Therapies 8. Diabetes, 9. Genetics, Nutrition, Endocrine Rheumatology 7. Medicine 10. Imaging 11. Women’s 12. Child Health Obesity & Infection, Ophthalmology Dermatology 14. Allergy, 15. Mental Health 16. Child & 13. Pharmaceutical Respiratory, of Older Adults Adolescent 17. Addictions 18. Psychosis Sciences Critical care & Dementia Mental Health & Anaesthetics 19. Behavioural & 20. Mood, Anxiety 21. Psychological Developmental & Personality Medical Psychiatry Disorder Health Policy and Evaluation Institute

  12. Research management Page 11 KHP Executive KCL Research Committee KHP Research Committee Experimental Medicine Basic Science Executive HPE Executive committee

  13. We are creating a platform to support experimental medicine across all three campuses Page 12 • State-of-the-art facilities are essential to facilitate Experimental Medicine • Within King’s Health Partners there is an extensive and growing range of core research facilities and underlying technical skills to support innovation and its rapid translation to care for patients • Clinical Research Facilities are being tailored to each of our hospital sites: Site Focus Co-funder On Stream St Thomas’ Cardiovascular, Nutritional, GSTT Charity, NIHR Opened 2008 Metabolic & Related studies BRC, Tate & Lyle plc Denmark Hill Neuroscience & psychiatric Wellcome Trust Late 2010 studies inc. PET & MRI facilities and cell therapy Guy’s Asthma, Allergy & GSTT Charity Opened May 2010 Immunology with a GMP cell NIHR BRC therapy suite • We have established a Joint Clinical Trials Office (JCTO) dedicated to overseeing the management of commercial trials

  14. Guy’s Tower Experimental Page 13 Medicine Hub Floor 16: comprehensive DH Biomedical Research Centre /JCTO Floor 15: CRF, the Joint Clinical Trials Office Floor 14: Phase 1 unit with Quintiles Floor 13: GMP manufacturing facility, operated by GSTFT and available for formulation of NCEs Floor 11: GMP suite attached to Assisted conception unit for ES lines

  15. The vision – a radical change in healthcare Page 15 To advance health and well-being by integrating world-class research, care, education and training through: • Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training • Integrating physical and mental healthcare to deliver a holistic approach to patient care • Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention • Developing a workforce that will transform healthcare – delivering innovation through education

  16. The Geography of Cartesian Dualism… Page 16

  17. Mental health in general hospitals Page 17 Physical disease in people A&E Emergency psychiatry with established mental disorders Major incidents and trauma Medically unexplained symptoms Mental health in general hospitals Perinatal disorders Substance misuse Health related Cognitive Coping and adjusting behaviours: impairments to disease • primary prevention Delirium and Comorbid depression dementia and anxiety • Secondary prevention Mental capacity

  18. Some examples Page 18 • Chronic fatigue syndrome • Viral hepatitis • Anxiety in cancer • Secondary prevention in diabetes

  19. Integrating physical and mental health care Page 19 • Psychological Medicine CAG • Aim to screen all patients admitted to acute Trusts for depression • Target appropriate interventions

  20. The vision – a radical change in healthcare Page 20 To advance health and well-being by integrating world-class research, care, education and training through: • Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training • Integrating physical and mental healthcare to deliver a holistic approach to patient care • Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention • Developing a workforce that will transform healthcare – delivering innovation through education

  21. From treatment towards the promotion of health Page 21 Health Indicator Lambeth Southwark Lewisham Greenwich Croydon Bromley Bexley Binge drinking adults Deaths from smoking Drug Misuse Early deaths: Cancer Early deaths: Heart disease & stroke Healthy eating adults Hospital stays due to alcohol Infant Mortality Life expectancy Mental Illness Obese Adults Obese Children Physically active adults Teenage Pregnancy Tuberculosis Violent Crime Key Worse than In line with Better than London average London average London average Source : Department of Health Community Health Profiles 2009

  22. Integrating community services Page 22 • Competed successfully for the community services of Lambeth and Southwark • Adds a further £100m business to our partnership • Should facilitate pathway redesign and shift of activity out of hospital

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