Ablation in Barrett's A Light, J Wayman, D Nylander RFA RFA probe - - PowerPoint PPT Presentation

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Ablation in Barrett's A Light, J Wayman, D Nylander RFA RFA probe - - PowerPoint PPT Presentation

Radiofrequency Ablation in Barrett's A Light, J Wayman, D Nylander RFA RFA probe inserted via catheter (360) or on end of endoscope. 10-12jcm2 energy <1sec Approved by NICE since 2010 Aims To audit our outcomes and complications of


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SLIDE 1

Radiofrequency Ablation in Barrett's

A Light, J Wayman, D Nylander

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SLIDE 2

RFA

RFA probe inserted via catheter (360) or on end

  • f endoscope.

10-12jcm2 energy <1sec Approved by NICE since 2010

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SLIDE 3

Aims

  • To audit our outcomes and complications of

Radiofrequency Ablation

  • To assess if providing this service is cost effective
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SLIDE 4

Methods

  • Retrospective data collection including patient

demographics, histology and extent of Barrett's pre and post treatment and any other treatments.

  • Basic cost analysis as per procedure and per

patient cost

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SLIDE 5

Results

  • Total of 8 patients over 4 year period
  • No complications
  • Median total number of treatments 1 (1-4)
  • Reversion from high to low grade dysplasia seen

in 5 patients (3 awaiting repeat biopsy)

  • Reduced length of Barrett's in 3 and resolution in 2

patients (3 awaited repeat endoscopy)

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SLIDE 6

Results

Age Grade Length Circumf. Length Pre treatment No. RFAs Post treatment Outcome 76 Mixed 15 9 EMR 1

  • Low grade and

reduced length

78 High 10 5 EMR 4 EMR

Low grade, now stable

75 High 3 EMR 2

  • Low, no

residual

45 High 7 EMR 1

  • Atypia,

ulceration

69 High

  • EMR

2

  • Low grade.

72 High 6 1

  • 1
  • Awaited

68 High 5 1

  • 1
  • Awaited

71 High 3

  • 1
  • Awaited
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SLIDE 7

Results combined

3 6 9 12 15 Dysplasia High Low Pre EMR Yes No Post EMR Yes No Total RFA sessions One Two Three Four Total treatments One Two Three Four Five Six

Number of Patients

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SLIDE 8

Cost

  • Hire of generator per day = £1200
  • Per treatment cost equipment = £1795
  • Total cost per treatment* = £ 2995
  • Mean cost per patient* = £4867 (£11'980 max)

(*excluding cost of endoscopy day-case)

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SLIDE 9

Conclusions

  • In our experience RFA has been safe and

effective.

  • Need longer term follow-up to assess if this is

longstanding

  • High financial cost however