+ =-#$&(%*#>$-)? @(A-(BC+:(##-&0+DEEE F - PowerPoint PPT Presentation

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_"OO(0)+]&N-$#EEE+ Tissue Engineering Example 1: Human Ear @:!$)!.4>A!BCCD!

_"OO(0)+]&N-$#EEE+ Tissue Engineering Example 2: Human Jaw E.03=$!$)!.4>A!BCCF!

_"OO(0)+]&N-$#EEE+ Tissue Engineering Example 2: Human Jaw E.03=$!$)!.4>A!BCCF!

_"OO(0)+]&N-$#EEE+ Custom Implants Example 3: 3D Printed Ribcage G0.3-.!$)!.4>A!BCHD!

:(##-&0+6;+G-#$"##-&0+X"(#>&0#EEE+ WXYC +10+(0L-0((O-0L+.($/*0-$#S+B/*)+*O(+)/(+I*#-$+ $&0$(N)#+*0<+*##".N>&0#+"#(<+-0+#)*>$#S+<?0*.-$#S + *0<+#)O(0L)/+&K+.*)(O-*%#\+ WXYC +Z/*)+.($/*0-$*%+NO&N(O>(#+*O(+$&..&0%?+"#(<+)&+ $/*O*$)(O-`(+.*)(O-*%+I(/*A-&O\+ WXYC +Z/*)+*O(+#&.(+K"0<*.(0)*%+<-^(O(0$(#+I()B((0+ )O*<->&0*%+(0L-0((O-0L+.*)(O-*%#+*0<+I-&%&L-$+ >##"(#\+ WXYC +Z/*)+-#+A-#$&(%*#>$-)?\+

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,*#-$+_&0$(N)#+-0+!($/*0-$#EEE+ WXYC +Z/*)+-#+:)O(0L)/+&K+!*)(O-*%#\+ ]/(+(^($)+&K+(M)(O0*%+K&O$(#+*$>0L+&0+*0+&Ia($)+ O(#"%>0L+-0+<(K&O.*>&0EEE+ U I.*+/!/(3/$')*J! !!!!!!!!!!!!!!!!!!!!!!!!!!M)0$**!.3-!*)0.+3! U I.*+/!.**:6'2(3*J!!!!!!!!!!!!!!!!!!!!!!!!! !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!M(4+-!8(-+$*!N%(6(5$3$(:*OA!*6.44!!!!!!!!! ! ! !! ! !-$7(06.2(3*! U I.*+/!)((4J! !!!!!!!!!!!!!!!!!!P$)%(-!(7!*$/2(3*!

;NN%-$*>&0+)&+,-&%&L-$*%+]-##"(#EEE+ WXYC +,*#(<+&0+%&*<c<-#N%*$(.(0)+.(*#"O(.(0)#S + B/*)+.($/*0-$*%+NO&N(O>(#+*O(+$&..&0%?+ "#(<+)&+$/*O*$)(O-`(+.*)(O-*%+I(/*A-&O\+ - Stress-strain � - Stiffness / elastic modulus � - Yield, ultimate, or failure load/stress � - Failure strain � - Poisson ’ s ratio � - Others (...fatigue strength, toughness, etc.) �

,*#-$+_&0$(N)#+-0+!($/*0-$#EEE+ 3MC+:)O(##U:)O*-0+G-*LO*.EEE+ A) Yield Stress C) Failure Stress B) Ultimate Stress D) Linear Elastic Region A x B C x ! Linear Elastic

;NN%-$*>&0+)&+,-&%&L-$*%+]-##"(#EEE+ WXYC +Z/*)+*O(+#&.(+K"0<*.(0)*%+<-^(O(0$(#+ I()B((0+)O*<->&0*%+(0L-0((O-0L+.*)(O-*%#+ *0<+I-&%&L-$+>##"(#\+ Flexion/Extension (L1-L5 Intact) 1st Cycle 2nd Cycle 3rd Cycle - Non-homogeneous � 6 4 - Large deformations � 2 Moment (Nm) - Non-linear � 0 -2 - Hysteresis � -4 - Viscoelastic � -6 -8 -20 -15 -10 -5 0 5 10 Flex. Angle (deg) Ext.

;NN%-$*>&0+)&+,-&%&L-$*%+]-##"(#EEE+ WXYC +_*0+B(+*NN%?+)/(+I*#-$+NO-0$-N%(#+&K+ .($/*0-$#+)&+I-&%&L-$*%+>##"(#\+++ T-E(ES+G&+&"O+*##".N>&0#+/&%<\V+ Assumptions: � Reality: � - Homogeneous � - Non-homogeneous � - Small deformations � - Large deformations � - Linear Elastic � - Non-linear � - Hysteresis � - Viscoelastic �

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B&%%&AC"D#+E@&.+%*#)+$%*##+ • ]*I%"0;#+;(E&@.-)>+ ! ,&0>+(0%*@I(.(0)+ ! H*-0+E@&.+M"@#-=#+ • B&&)+*0*)&.>+ http://www.foothealthfacts.org/ footankleinfo/haglunds-deformity.htm • Z-##($=&0+?-;(&P#R+

B&&)O+.&=&0+ sagittal plane dorsiflexion neutral plantar flexion

B&&)O+.&=&0+ frontal plane eversion or valgus inversion or varus neutral

B&&)O+.&=&0+ transverse plane abduction or adduction or external rotation internal rotation neutral

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