United Nations Security Council Resolution 1540: Emerging Trends, - - PowerPoint PPT Presentation

United Nations Security Council Resolution 1540:

Emerging Trends, Sharing of Experiences, Lessons Learned, and Effective Practices Dana Perkins, PhD 1540 Committee Expert

Biological Weapons Convention Meeting of States Parties Side event on: Developments in Science and Technology 09 December 2013, Geneva, Switzerland

Unless otherwise specified, the opinions presented here are those of the presenter and may not necessarily reflect the views of the 1540 Committee, its Group of Experts, or the UN Security Council

Quo vadis, Biotech ?

“Even when we know the function of every gene in the genome, we still don’t understand how the body or the brain work, nor how they adapt and change with age, training, or disease. Now is the time to move beyond reductionism and construct a new biology of complex life systems. To do this we need every tool in the toolkit, and we need to invent new technologies and disciplines“

• Carla J. Shatz , Director of the Bio-X Program, Stanford University, US -

A futu uture w whe hen:

 Food i

is p plenty ty a and h healthy thy  Ene nergy is is c clean a and nd sustai ainab able le  The he go good he health o

• f p

people, an animals, plan lants an and t the environment i is the the norm

• Bio-medicine

– Complex molecular devices for tissue repair – Smart therapeutics – Novel delivery systems – Personalized genomic medicine – In vivo drug synthesis by microbiome manipulation

• Environment and energy

– Bioremediation – “Green” energy microbial production – Safe GMOs

• In vitro synthesis of complex biopharmaceuticals
• Sustainable “green” chemical (microbial) industry
• Production of smart (bio)materials

• Nano-medicine

– Enhanced prostethics – Nano-structured implants/ scaffolds for tissue regeneration – In vivo nano-sensors – Q-dot single protein label – Nano-manufacturing /liquid glass – Dx/Rx nano-shells/ dendrimers/bots

• Nano-enhanced physical

and cognitive performance

• Exploiting quantum effects

for smart nano-materials, bionics, biomimetics, neuromorphic engineering, brain-machine interface

http://www.ngm.com

“In the near future, nanotech-enabled technologies intended for use in the body will erase any remaining distinction between “therapy” and “enhancement” and could change, quite literally, the definition of what it means to be human…Homo sapiens 2.0…”- ETC Group

Quo vadis, Nanotech ?

Nano-Armageddon: the “gray goo” scenario

• Gray Goo – a term coined

by Eric Drexler

• Hypothetical end-of-the-

world scenario involving

• ut-of-control, rapidly self-

replicating nano-robots that consume all organic matter

• n Earth

Shane Hope’s representation of the “gray goo armageddon”, part of the artist’s show on trans-humanism, called "Your Mom Is Open Source” at the Winkelman Gallery, New York City

Bio-Armageddon

• the “green goo” scenario -

Between the “green goo” and an uncertain future…

• Ability of individuals to harness the microbe

power for nefarious purposes

• Environmental and ethical challenges

posed by emerging technologies and the ensuing public debate

• Human augmentation systems
• Pace of changing the traditional institutional

and regulatory frameworks to keep up with technological advances and science dynamics such as the convergence of nano-, bio-, information and materials technology

• Ability to develop countermeasures to

threats as a measure of deterrence

• Omnipresence of insecurity, including

terrorism

Fall 2010: Al-Qaeda’s Inspire Magazine calls

• n “those mujahid brothers with degrees in

microbiology or chemistry…to develop a weapon of mass destruction”

http://www.selectagents.gov/resources/Addressing%20Biosecurity-%20Roles%20and%20Responsibilities%20of%20the%20Science%20and%20Security%20Communities.pdf

“The [Lyon] lab was located in a spare bedroom that doubled by day as a sewing

• room. French police say Benchellali, fresh

from training camp in the Pankisi Gorge, would lock himself in the room and work through the night on his mysterious projects, the nature of which he kept to himself. In fact, French police say, he was experimenting with a variation of one of the recipes he learned abroad: a ricin

concoction laced with the toxin that causes botulism”.

http://www.washingtonpost.com/wp-dyn/articles/A2159-2004May4_2.html

Resolution 1540 (2004): A Response to Threats to International Peace & Security

Security Council Meets on Non-Proliferation

• f WMDs

UN Photo: Eskinder Debebe, 28 April 2004

Resolution 1540 (2004) imposes binding obligations on all States to adopt legislation to prevent the proliferation of nuclear, chemical and biological weapons, and their means of delivery, and establish appropriate domestic controls over related materials to prevent their illicit trafficking “to non-State actors, in particular for terrorist purposes”

Non-State actor: individual or entity, not acting under the lawful authority of any State in conducting activities which come within the scope of this resolution Means of delivery: missiles, rockets and other unmanned systems capable of delivering nuclear, chemical,

• r biological weapons, that are specially designed for such use

Related materials: materials, equipment and technology covered by relevant multilateral treaties and arrangements, or included on national control lists, which could be used for the design, development, production or use of nuclear, chemical and biological weapons and their means of delivery

Emerging Trends: Means of Delivery

“…From a combined reading of the definition of “means of delivery” and “related materials”, it is clear that a range of “wide area” RCA means of delivery may potentially fall under the scope of resolution 1540… However, there is currently a lack of definitional clarity and continuing ambiguity concerning which forms of “wide area” RCA munitions are prohibited under the CWC and BWC. In addition to the implications for effective implementation of these two Conventions, such ambiguities have potentially dangerous consequences for the implementation of resolution 1540 (2004) obligations which are applicable to all UN Member States, thereby increasing the risk of the proliferation of such “wide area” RCA munitions to, and misuse by, non-State actors…”

Resolution 1540 (2004) and the Gain-of-Function Research on H5N1 virus

http://www.nature.com/news/specials/mutantflu/index.html

“The [Dutch] court argued that, more broadly, decisions on what is and what is not research with potential consequences for international proliferation cannot be left to individual researchers without compromising states’ obligations under UN resolution 1540 passed in 2004, which requires states to adopt legislation to counter the proliferation

• f nuclear, chemical and biological

weapons…”

http://blogs.nature.com/news/2013/09/court-upholds-need-for-export-permits-for-risky-flu-research.html

1 2 3 4

Managing risks in life sciences research

“The 2 articles…highlight an important alternative mechanism for management of risk in life sciences research… The authors of these articles, believing that the sequence information of BoNT/H poses an immediate and unusually serious risk to society, and that the information was unlikely to be already in the hands of those who would seek to do harm, decided to exercise voluntary prepublication control and to withhold this specific information...” – David A. Relman, JID, 07 October 2013

Biological Risk Management, BWC, and resolution 1540 (2004)

• Safeguarding biological agents,

facilities, and technology against nefarious uses is a common objective of the Biological Weapons Convention and resolution 1540 (2004)

• Ensuring biosafety and

biosecurity is a prerequisite for any life sciences activity and for upholding the trust of the public and that of the decision makers

Measures to account for / secure / Physically protect means of delivery Regulations for physical protection

• f facilities /

materials / transports Regulations for genetic engineering work

Biosafety / Biosecurity

1540 matrix fields

Engaging DIY Bio: excerpts from documents mentioned in the 2013 US report to the 1540 Committee

“…the U.S. Government should…utilize strategies that (1) promote positive motives for participation in amateur biology and stigmatize negative ones, and (2) lay the groundwork for developing a culture of responsibility in the hobbyist community… … find ways to collaborate on the organization of conferences and workshops designed to provide opportunities for face-to-face interaction with the DIY community and interested amateur biologists generally. These kinds of events would provide

• pportunities to convey important educational content about not
• nly dual use research issues, but also biosafety and responsible

science…”

“The beneficial nature of life science research is reflected in the widespread manner in which it occurs. From cutting-edge academic institutes, to industrial research centers, to private laboratories in basements and garages, progress is increasingly driven by innovation and open access to the insights and materials needed to advance individual initiatives...”

Codes of conduct Building a security culture and responsible conduct of science

Societal vigilance

Education, training & awareness raising A multi-factorial solution to the multi-faceted problem of WMD proliferation

Sharing of experience, lessons learned and effective practices in bio risk management

“On behalf of the Security Council Committee established pursuant to resolution 1540 (2004), I have the honour to call your attention to the following provisions of resolution 1977 (2011). Operative paragraph 10 of resolution 1977 (2011) urges the 1540 Committee to continue to engage actively with States and relevant international, regional and subregional organizations to promote the sharing of experience, lessons learned and effective practices, in the areas covered by resolution 1540 (2004) drawing, in particular, on information provided by States as well as examples of successful assistance, and to liaise on the availability of programmes which might facilitate the implementation of resolution 1540 (2004). Operative paragraph 12 of resolution 1977 (2011) requests the 1540 Committee, with the support of the group of experts, to identify effective practices, templates and guidance, with a view to develop a compilation, as well as to consider preparing a technical reference guide about resolution 1540 (2004) to be used by States on a voluntary basis in implementing resolution 1540 (2004). In this context, I would appreciate it if your Government would inform the 1540 Committee of its relevant effective experience, lessons learned and effective practice, in the areas covered by resolution 1540 (2004). Such information will be used by the 1540 Committee in accordance with operative paragraph 12 of resolution 1977 (2011) to develop a compilation that will be posted

• n the 1540 Committee’s website…”— Ambassador Oh Joon, Chair of the 1540

Committee, Letter to States dated 04 November 2013 Oh Joon 1540 Committee Chair, Ambassador and Permanent Representative of the Republic of Korea to the United Nations

Address submissions to: Ambassador Oh Joon, 1540 Committee Chair 730 Third Avenue, TB-08040E United Nations, New York, NY 10017, USA Fax: 212-963-1300 Email: sc-1540-Committee@un.org

Dana Perkins, PhD

1540 Committee Expert United Nations 300 East 42nd St., Suite IN-03074H New York, NY 10017 Tel: +1 (917) 367 6023 (office) E-mail: PerkinsD@un.org Contact information

Collective e-mail: 1540experts@un.org Website: http://www.un.org/sc/1540