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THE LIBERIAN INSTITUTE FOR BIOMEDICAL RESEARCH DIVISION OF - - PowerPoint PPT Presentation
THE LIBERIAN INSTITUTE FOR BIOMEDICAL RESEARCH DIVISION OF - - PowerPoint PPT Presentation
THE LIBERIAN INSTITUTE FOR BIOMEDICAL RESEARCH DIVISION OF PHMR/NPHIL REPUBLIC OF LIBERIA PRE-EVD CHALLENGES BASIC HEALTH INDICATORS OF HEALTH SERVICES Health Workforce per 10 000 population Liberia African Region Average Global Average
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PRE-EVD CHALLENGES
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Health Workforce per 10 000 population
Physicians Physician Assistants (PAs) Nursing & Midwifery Personnel Dentistry Personnel Pharmaceutical Personnel Hospital Beds Density Rural Hospital per 10,000 pop Liberia 0.3 0.8 5.2 0.07 0.1 8 0.04 African Region Average 2.6 n/a 12.0 0.5 0.9 9 n/a Global Average 14.1 n/a 29.2 2.7 4.3 27 n/a
BASIC HEALTH INDICATORS OF HEALTH SERVICES
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Lack of basic infrastructure to conduct high quality research Limited experience in basic and/or clinical research Inadequate laboratory facilities and Repository for samples Structural challenges to ethical and/or regulatory processes Environmental & people unpreparedness for clinical trials Significant distrust in the health and/or political systems Partners research agenda unaligned to country’s needs
Sub-Regional Pre-EVD Challenges….
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ROLE PLAYED BY LIBR DURING THE EVD OUTBREAK
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EMERGENCY RESPONSE
LIBR demonstrated that it was a key public health asset,
as evidenced by the EVD response
Upon hearing about EBOLA in Guinea, LIBR quickly
mobilized few of its staff and travelled to the Foya District, 25 March 2014, that became the Epicenter of the EVD Outbreak
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EMERGENCY RESPONSE
Participating in Daily Lofa County Coordination
meetings to plan and evaluate Ebola Response Activities
Worked along with County Health to vigorously
carry out education and social mobilization in town and villages
Meeting with traditional and religious leaders Meeting with youth and women’s groups Meeting with political local leaders
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EMERGENCY RESPONSE
Epidemiological Investigation of New Ebola Cases Ebola Contact Tracing Training of Burial Teams Establishing and Monitoring of Kolahun District Isolation Unit for new
arrival in Kolahun District
Decision of District elders and chiefs was strick restoration of movement
- f strangers and visitors, excluding response team member in the district
and among towns and villages.
For citizens of the district come into the district to seek refuge, the were
not allow to go to there villages and towns, hence Isolation units were used to harbor these category of people
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LABORATORY FACILITY PRIOR TO EBOLA
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CLINICAL RESEARCH CENTER - LOFA
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SATILLITE FACILITY
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CAPACITY BEFORE EBOL
A PHYSICIAN ASISTANT TRAINED LABORATORY TECHNICIAN
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SPECIALIED DIAGNOSTIC CAPACITY
Although limited, LIBR quickly developed into a lab that
served the EVD outbreak with contribution mainly by NAMRU-3 followed by a whole host of partners.
In collaboration with NIH and US DoD LIBR provided
containment and critical PCR diagnostic capabilities for the Ebola virus detection.
In the drive to further improve our capacity, we
engaged USAMRID (US DOD) to assist LIBR with genomic equipment (Miseq)
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SPECIALIED DIAGNOSTIC CAPACITY
USAMRID also assisted us with training on the use
- f the Miseq equipment.
During of the sporadic outbreak of EBOLA in
March 2015, LIBR in collaboration with our USAmrid colleagues demonstrated for the first time that EBOLA could be transmitted sexual.
Today, LIBR has a Liberian who is capable of
genomic sequencing. We are making all effort for him and few more of our staff to get further training.
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Infrastructure & Partnership….
NAMRU PCR TRAINING
FIRST LIBERIAN DIAGNOSING EBOLA WITH NIH & NAMRU SUPPORT
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POST EBOLA LAB CAPACITY
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MENTORSHIP
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Infrastructure & Partnership….
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System Strengthening & Coordination
- Ethics, Regulatory, Social Mobilization, etc.
Capacity Enhancement for Rapid Response
- Human Resources, Ethics, Regulatory, etc.
Infrastructure to Address Emerging & Re-Emerging Diseases
- BSL 2-3, Bio-bank, etc.
Stimulate Research Programs
- Basic, behavioral, biomedical & clinical studies
Post-EVD R&D Roadmap ….
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ZMAPP Convalescent Plasma Vaccines Therapeutics EVD Survivors RDTs Behavioural Psychosocial Seroprevalence Biomedical
Snapshot of Research Activities
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