The Impact of Social Capital on Patients with Multiple Sclerosis. - - PowerPoint PPT Presentation

The Impact of Social Capital on Patients with Multiple Sclerosis.

Saúl Reyes, Sebastián Suarez, Kimberley Allen-Philbey, Alison Thomson, Gavin Giovannoni

Social Capital

Reyes S., Giovannoni G., Thomson A. Social capital: Implications for neurology. Brain Behav 2019;9:e01169.

• Resources derived from the social interaction

between individuals and groups:

–Networks. –Organizations. –Social trust within a community. –Norms of reciprocity.

Social Capital and Health

Dhand A et al. Nat Rev Neurol. 2016

Stroke AD

Objective

• To investigate the effect of SC on the physical and

psychological impact of MS.

Methods

• A cross-sectional study was conducted among 236

pwMS at The Royal London Hospital, London, UK.

• Participants completed an online survey including:

MSIS-29, HADS, self-reported EDSS and a SC questionnaire.

• The SC questionnaire assessed social networks,

trust and norms, personal relationships and civic engagement.

Methods

• Kendall's tau correlation test was performed to

measure the correlation between SC and MSIS-29.

• Multiple linear regressions were conducted to find

the best outcome prediction model.

• Assumptions

were checked for each model: independence

• f

errors, multicollinearity and homoscedasticity.

Results

! Marital status Married 134 56.8 Other 102 43.2 Employment status Employed 140 59.3 Unemployed 96 40.7 ! Sex Female 168 71.2 Male 68 28.8 Type of MS RR 180 76.3 SP 34 14.4 PP 22 9.3 Race White 172 72.9 Asian 27 11.4 Black 21 8.9 Other/Not stated 16 6.8 Living arrangements Family 179 75.8 Friends 11 4.7 Strangers 3 1.3 Alone 43 18.2 Education College or more 190 80.5 Secondary school 42 17.8 Primary school or less 4 1.7 ! n % ! Age (yrs) 43.5 35-52 Disease duration (yrs) 8 4-13 Income decile 5 3-7.8 EDSS 4 2.5-6.5 HADS-A 8 4.8-11.3 HADS-D 6 3-9 MSIS-29-PHYS 23.7 8.8-57.5 MSIS-29-PSYCH 38.9 16.7-55.6 Social capital Relationships 3 3-4 Social networks 1 1-2 Civic engagement 3 2-4 Trust and norms 4 2-5 Total 12 9-14 ! Median IQR ! n %

Results

MSIS-29-PSYCH MSIS-29-PHYS SC

Correlation between SC and MSIS-29

SC

Results

* Adjusted for EDSS, Type of MS, DMT, disease duration, age, ethnicity, HADS-D, income, marital status and living arrangements. ** Adjusted for EDSS, Type of MS, DMT, disease duration, age, education status, income and time in current home.

! Estimate! Standard Error P Value Adjusted R2 value MSIS-29-PHYS* Total SC

• 0.09

0.34 0.800 0.78 SC domains 0.77 Relationships

• 0.92

1.13 0.418 Social Networks 0.22 1.26 0.865 Civic Engagement 0.02 0.73 0.978 Trust and norms 0.12 0.64 0.850 MSIS-29-PSYCH** Total SC

• 1.97

0.44 <0.001 0.34 SC domains 0.37 Relationships

• 6.29

1.41 <0.001 Social Networks 1.13 1.62 0.486 Civic Engagement

• 0.28

0.98 0.774 Trust and norms

• 1.66

0.83 0.046

Conclusions

• Higher levels of SC were associated with lower

self-rated psychological impact of MS.

• Emerging

evidence

• n

SC and MS should be translated into interventions for health-promoting purposes.

What's next?

SC Interven'on SC Interven*on

The Impact of Social Capital on Patients with Multiple Sclerosis.

Saúl Reyes, Sebastián Suarez, Kimberley Allen-Philbey, Alison Thomson, Gavin Giovannoni