SLIDE 1 John Inglis, PhD
Co-founder, bioRxiv and Executive Director, Cold Spring Harbor Laboratory Press inglis@cshl.edu Twitter @JohnRInglis
The bioRxiv preprint service
COASP 2016, Arlington VA, September 22, 2016
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Preprint (n): a complete but unpublished manuscript yet to be certified by peer review “Because the process [of peer review] can be lengthy, authors use the bioRxiv service to make their manuscripts available as preprints before peer review, allowing other scientists to see, discuss, and comment on the findings immediately”
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- Simple submission process
- Authors’ PDFs – no
typesetting/mark-up
- Posting almost immediate,
with screening but no peer review
posted any time
are free
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Why did we start bioRxiv?
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Cold Spring Harbor Laboratory, NY
SLIDE 6 Research at Cold Spring Harbor
- 600 scientific staff
- 50 research groups
- Molecular biology and genetics
- Cancer
- Neuroscience
- Plant biology
- Genomics and bioinformatics
- Quantitative biology
SLIDE 7 Science education & communication at Cold Spring Harbor
Conferences
- Meetings
- The Banbury Center
- Cold Spring Harbor Asia, Suzhou, China
Professional education
- Residential lab and lecture courses
- Watson School of Biological Sciences
Publishing
- Cold Spring Harbor Laboratory Press
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Research journals Review journals Books
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The mission of Cold Spring Harbor Laboratory
To create knowledge and to share knowledge
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“It’s ridiculous I have to wait months to read a paper while it goes through peer review…let me decide for myself whether it’s any good” “Think how much time is wasted!”
What biologists were saying
“I am writing a grant but the paper is not going to be published by the time I submit. The solution is a preprint server that can be referenced”
SLIDE 11 arXiv: a million preprints in physics, math, comp sci, quant bio
- Established 1991
- Mechanism for sharing
findings prior to publication & establishing priority
- In 2012, number of biology
submissions increased
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Launched November 2013
SLIDE 13 For-profit start-up, conduit to PeerJ journal For-profit, public peer-review journal
Commercial models
For-profit, host for figures, partial papers, etc.
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Non-profit funded by Cold Spring Harbor Laboratory & Lourie Foundation, hosted by HighWire Press
Non-profit, publisher-neutral models
Non-profit funded by Cornell, libraries & foundations, hosted by Cornell Non-profit hosted by Open Science Framework
ChemRxiv
Non-profit to be launched by American Chemical Society Non-profit owned by SIPS, hosted by Open Science Framework
SLIDE 15 Benefits of preprints
- Rapid transmission of results
- Pre-publication feedback/discussion
- Visibility, especially for early-career
scientists
- Evidence of productivity for grant/hiring
committees
SLIDE 16 Accelerating communication
bioRxiv
Data courtesy of Stephen Royle
Received-published Received-accepted Accepted-published
SLIDE 17 bioRxiv screening
Author submits ms Affiliate screens ms Staff check ms
Manuscript Posted
Author proofs ms
Rejected (not science, nonsense, health threat)
Author resubmits ms Staff check ms Author proofs ms
versioning Viewable by Affiliates Viewable by all Affiliate flags paper for attention Affiliate oks manuscript
SLIDE 18 bioRxiv features
- Posted manuscript date-stamped + given a DOI (citable)
- Choice of article type (New, Confirmatory, or Contradictory Results)
- 26 subject categories
- Choice of license (CC0, CC BY, CC BY-NC, CC BY-ND, CC BY-NC-ND, all rights
reserved)
- Article metrics and altmetrics
- Commenting
- Links to published versions
- Indexed in Google Scholar
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SLIDE 24 Posts
- 6000 posted manuscripts (>90% approved)
- 30% revised (many more than once)
- 26,000 authors
- 2600 institutions
- 42 countries
- 60% of manuscripts published, in >300 journals
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Posts
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bioRxiv by subject
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arXiv by subject
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Usage
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Direct commenting Email
Feedback/discussion
Blogs Social media
?
58K
SLIDE 30 Progress
- Behavior change: more biologists posting/reading preprints
- Policy change: more journals allow preprint posting
- Rule change: NIH biosketch can now cite non-peer-reviewed
publications
- Change in community awareness
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ASAPbio impact
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ASAPbio survey
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Change in journal policies
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Changing citation policies
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Changing indexing policies
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Improving discovery
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Improving discovery
SLIDE 38 Formal publication
Partnering with journals
Submission
Peer review
Yur journal here One-click submission Simultaneous submission Preprint posted
SLIDE 39 Formal publication
Further integration?
Submission
Peer review
Yur journal here Preprint posted Commenting Social media
?
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Conference integration
SLIDE 41 Automated feeds
Partnering with societies
Curated ‘channels’ Meeting ‘channels’ Journals Discussion
SLIDE 42 bioRxiv as a communication hub
Journals
Meetings Blogs Confirmatory results Contradictory results
Discussion Reproducibility Certification
SLIDE 43 Next priorities
- Expanding the available journal submission choices
- Expanding ingestion of manuscripts from journals
- Developing APIs for third party services
- Expanding governance
- Adding services for authors, eg Hypothes.is
- Continuing advocacy for preprints with societies, funders, etc.
- Consolidating future funding
SLIDE 44 Open issues
- Priority claims and scooping
- Clinical scope
- Clinical criteria
- Citation linking/summing
- Discoverability
- Retractions
- License conflicts
SLIDE 45 Grateful thanks to:
The bioRxiv Team
Jan Argentine Linda Sussman Ted Roeder Richard Sever Inez Sialiano
The bioRxiv Affiliates and Advisors HighWire Press Partner Publishers Partner Submission Systems Cold Spring Harbor Laboratory The Lourie Foundation