The bioRxiv preprint service John Inglis, PhD Co-founder, bioRxiv - - PowerPoint PPT Presentation

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The bioRxiv preprint service John Inglis, PhD Co-founder, bioRxiv - - PowerPoint PPT Presentation

The bioRxiv preprint service John Inglis, PhD Co-founder, bioRxiv and Executive Director, Cold Spring Harbor Laboratory Press inglis@cshl.edu Twitter @JohnRInglis COASP 2016, Arlington VA, September 22, 2016 Preprint ( n) : a complete but


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John Inglis, PhD

Co-founder, bioRxiv and Executive Director, Cold Spring Harbor Laboratory Press inglis@cshl.edu Twitter @JohnRInglis

The bioRxiv preprint service

COASP 2016, Arlington VA, September 22, 2016

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Preprint (n): a complete but unpublished manuscript yet to be certified by peer review “Because the process [of peer review] can be lengthy, authors use the bioRxiv service to make their manuscripts available as preprints before peer review, allowing other scientists to see, discuss, and comment on the findings immediately”

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  • Simple submission process
  • Authors’ PDFs – no

typesetting/mark-up

  • Posting almost immediate,

with screening but no peer review

  • Revised versions can be

posted any time

  • Submission and access

are free

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Why did we start bioRxiv?

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Cold Spring Harbor Laboratory, NY

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Research at Cold Spring Harbor

  • 600 scientific staff
  • 50 research groups
  • Molecular biology and genetics
  • Cancer
  • Neuroscience
  • Plant biology
  • Genomics and bioinformatics
  • Quantitative biology
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Science education & communication at Cold Spring Harbor

Conferences

  • Meetings
  • The Banbury Center
  • Cold Spring Harbor Asia, Suzhou, China

Professional education

  • Residential lab and lecture courses
  • Watson School of Biological Sciences

Publishing

  • Cold Spring Harbor Laboratory Press
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Research journals Review journals Books

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The mission of Cold Spring Harbor Laboratory

To create knowledge and to share knowledge

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“It’s ridiculous I have to wait months to read a paper while it goes through peer review…let me decide for myself whether it’s any good” “Think how much time is wasted!”

What biologists were saying

“I am writing a grant but the paper is not going to be published by the time I submit. The solution is a preprint server that can be referenced”

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arXiv: a million preprints in physics, math, comp sci, quant bio

  • Established 1991
  • Mechanism for sharing

findings prior to publication & establishing priority

  • In 2012, number of biology

submissions increased

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Launched November 2013

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For-profit start-up, conduit to PeerJ journal For-profit, public peer-review journal

Commercial models

For-profit, host for figures, partial papers, etc.

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Non-profit funded by Cold Spring Harbor Laboratory & Lourie Foundation, hosted by HighWire Press

Non-profit, publisher-neutral models

Non-profit funded by Cornell, libraries & foundations, hosted by Cornell Non-profit hosted by Open Science Framework

ChemRxiv

Non-profit to be launched by American Chemical Society Non-profit owned by SIPS, hosted by Open Science Framework

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Benefits of preprints

  • Rapid transmission of results
  • Pre-publication feedback/discussion
  • Visibility, especially for early-career

scientists

  • Evidence of productivity for grant/hiring

committees

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Accelerating communication

bioRxiv

Data courtesy of Stephen Royle

Received-published Received-accepted Accepted-published

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bioRxiv screening

Author submits ms Affiliate screens ms Staff check ms

Manuscript Posted

Author proofs ms

Rejected (not science, nonsense, health threat)

Author resubmits ms Staff check ms Author proofs ms

versioning Viewable by Affiliates Viewable by all Affiliate flags paper for attention Affiliate oks manuscript

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bioRxiv features

  • Posted manuscript date-stamped + given a DOI (citable)
  • Choice of article type (New, Confirmatory, or Contradictory Results)
  • 26 subject categories
  • Choice of license (CC0, CC BY, CC BY-NC, CC BY-ND, CC BY-NC-ND, all rights

reserved)

  • Article metrics and altmetrics
  • Commenting
  • Links to published versions
  • Indexed in Google Scholar
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Posts

  • 6000 posted manuscripts (>90% approved)
  • 30% revised (many more than once)
  • 26,000 authors
  • 2600 institutions
  • 42 countries
  • 60% of manuscripts published, in >300 journals
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Posts

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bioRxiv by subject

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arXiv by subject

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Usage

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Direct commenting Email

Feedback/discussion

Blogs Social media

?

58K

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Progress

  • Behavior change: more biologists posting/reading preprints
  • Policy change: more journals allow preprint posting
  • Rule change: NIH biosketch can now cite non-peer-reviewed

publications

  • Change in community awareness
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ASAPbio impact

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ASAPbio survey

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Change in journal policies

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Changing citation policies

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Changing indexing policies

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Improving discovery

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Improving discovery

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Formal publication

Partnering with journals

Submission

Peer review

Yur journal here One-click submission Simultaneous submission Preprint posted

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Formal publication

Further integration?

Submission

Peer review

Yur journal here Preprint posted Commenting Social media

?

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Conference integration

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Automated feeds

Partnering with societies

Curated ‘channels’ Meeting ‘channels’ Journals Discussion

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bioRxiv as a communication hub

Journals

Meetings Blogs Confirmatory results Contradictory results

Discussion Reproducibility Certification

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Next priorities

  • Expanding the available journal submission choices
  • Expanding ingestion of manuscripts from journals
  • Developing APIs for third party services
  • Expanding governance
  • Adding services for authors, eg Hypothes.is
  • Continuing advocacy for preprints with societies, funders, etc.
  • Consolidating future funding
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Open issues

  • Priority claims and scooping
  • Clinical scope
  • Clinical criteria
  • Citation linking/summing
  • Discoverability
  • Retractions
  • License conflicts
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Grateful thanks to:

The bioRxiv Team

Jan Argentine Linda Sussman Ted Roeder Richard Sever Inez Sialiano

The bioRxiv Affiliates and Advisors HighWire Press Partner Publishers Partner Submission Systems Cold Spring Harbor Laboratory The Lourie Foundation