TB TB-HI HIV V CO CO-INFE FECTI TION SITUATION IN PAKISTAN 7 - - PowerPoint PPT Presentation

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TB TB-HI HIV V CO CO-INFE FECTI TION SITUATION IN PAKISTAN 7 - - PowerPoint PPT Presentation

TB TB-HI HIV V CO CO-INFE FECTI TION SITUATION IN PAKISTAN 7 th Annual Public Health Conference 2016 at Health Services Academy, Islamabad Dec 14, 2016 Dr. Abdul Khalique Ghauri ri Program Coordinator National TB


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SLIDE 1

TB TB-HI HIV V CO CO-INFE FECTI TION SITUATION IN PAKISTAN

7th Annual Public Health Conference 2016 at Health Services Academy, Islamabad Dec

14, 2016

  • Dr. Abdul

Khalique Ghauri ri

Program Coordinator National TB Control Program Pakistan

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SLIDE 2

BACKGROUND

  • TB

and HIV are major public health problems worldwide and have synergistic affect

  • In

Pakistan, the prevalence

  • f

TB is very high

  • Ranks

5th amongst High TB Burden countries in the world

  • Ranks

4th High Burden country for Multi-Drug Resistant (MDR) TB

  • The

country is experiencing Concentrated Epidemic

  • f

HIV/AIDS with prevalent risk factors

  • With

an enormous burden

  • f

TB, and progressing epidemic

  • f

HIV especially among certain key populations, TB-HIV Co- infection is an emerging challenge

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SLIDE 3

OBJECTI TIVES

  • To

assess the current situation

  • f

TB-HIV Co-infection in Pakistan

  • To

identify gaps in services being provided to manage these patients

  • To

identify the constraints in implementation

  • f

TB-HIV Collaboration interventions

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SLIDE 4

METHODOLOGY

  • Retrospective

study was designed to analyze the data collected from Sentinel Sites

  • f

TB Control Program and ART Centers

  • f

AIDS Control Program, both implementing TB-HIV Collaboration interventions under The Global Fund grants since 2008.

  • HIV

Screening carried

  • ut

at 18 Sentinel Sites

  • f

TB Control Program through rapid test after taking consent and counseling

  • Confirm

ation is done through AIDS program ’s Reference Labs

  • r

Surveillance Centers

  • n

Elisa / Western Blot

  • PLHIV

regularly undergo screening

  • f

TB symptoms at 21 ART Centers

  • f

AIDS Control Program

  • Diagnosis
  • f

TB is done through Clinical Exam ination, Sputum Microscopy, Radiology, Histopathology and

  • ther

relevant tests

  • Reports
  • f

the specialized surveys conducted during the same period were also used, in addition to WHO & UNAIDS Reports

  • Proceedings
  • f

Quarterly Meetings

  • f

Provincial TB-HIV Coordination Committees were reviewed for identification

  • f

gaps and constraints in implementation

  • f

TB-HIV Collaboration

  • TB-HIV

Collaboration Framework agreed by both programs was used as reference document.

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SLIDE 5

TB Cases Notified ed (Year 2007 to 2015)

88747 100103 101887 104263 105748 110545 111682 122537 124900 103629 106213 112948 105623 103826 109425 118814 120350 127677 33986 34386 43416 45443 45537 49738 52646 57463 60030

20000 20000 40000 40000 60000 60000 80000 80000 100000 120000 140000

2007 2008 2009 2010 2011 2012 2013 2014 2015

New Sputum m Smear r Positive New Pulmo monary ry Sputum m Smear r Micro roscopy Negative New Extra ra Pulmo monary ry

Year 2007 2007 2008 2008 2009 2009 2010 2010 2011 2012 2013 2014 2015 TOTAL Total TB Cases Notifie ied

234,100 248,684 267,451 269,290 270,422 285,410 298,476 314,872 331,809 2,520,514

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SLIDE 6

TB Pa Patien ents Screen ened ed for HIV and found HIV + (Year r 2008 – 2015) 2015)

Sentinel Site Total Screened Found HIV Positive Percentage PUNJAB AB

1 Mayo Hospital Lahore 7,442 6 0.08% 2 Serv rvice ces Hospital Lahore 1,895 1 0.05% 3 Gulab Devi Hospital Lahore 11,736 17 17 0.14% 4 Allied Hospital Faisalabad 3,184 60 60 1.88% 5 Nishter Hospital Multan 4,717 10 10 0.21% 6 RGH Rawalpindi 1,823 0.00%

30,797 94 94 0.31%

KHYBER ER PAKHTUNKHWA

7 Lady Reading Hospital Peshawar 1,996 5 0.25% 8 DHQ Hospital Kohat 3,860 1 0.03%

5,856 6 0.10%

BALOCH CHISTAN AN

9 BMCH Quetta

1,853 10 10 0.54%

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SLIDE 7

TB Pa Patien ents Screen ened ed for HIV and found HIV + (Year r 2008 – 2015) 2015)

Sentinel Site Total Screened Found HIV Positive Percentage SINDH DH

10 Ojha Institute

  • f

Chest Diseases, Khi 6,213 49 49 0.79% 11 Malir Chest Clinic, c, Karach chi 2,092 2 0.10% 12 Civil Hospital, Karach chi 2,927 17 17 0.58% 13 LUMHS Hospital, Hyderabad 2,944 11 11 0.37% 14 PMCH Banazirabad, Nawabshah 5,267 9 0.17% 15 Civil Hospital, Mirp rpurk rkhas 3,339 1 0.03% 16 GMMCH, Sukkur 2,671 17 17 0.64% 17 CMCH, H, Lark rkana 5,603 82 82 1.46%

31,056 188 0.61%

ICT

18 PIMS

2,354 3 0.13%

TOTAL 71,196 301 0.42%

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SLIDE 8

HIV Epidemic

  • The

estimated number

  • f

HIV positive cases in Pakistan are > 100,000

City IDUs (% (%age) HSWs (% (%age) MSWs (% (%age) FSWs (% (%age)

DG Khan

49.6

0.5 Faisalabad

52.5

3.9 0.3 Gujrat

46.2

Lahore

30.8 5.2

1.7 0.5 Multan

24.9

1.1 1.9 0.3 Pakpattan 3.3 Rahim Yar Khan

14.9

Sargodha

40.6

3.7 0.3 Rawalpindi 4.2 0.6 Dadu

16.0

Karach chi

42.2 12.0 5.9

1.9 Lark rkana

18.6 14.9

3.1 1.9 Sukkur

19.2 6.2

2.2 0.8 Hari ripur

7.9

  • 0.9

Peshawar

20.0

1.1 Quetta

7.1

2.7 1.1 Turb rbat

21.4

HIV prevalence in risk groups-2011

Ref: HASP National Dissemination January, 2012, Islamabad

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SLIDE 9

Situation of TB among HIV infec ected ed persons

  • 19,399

HIV Positive ve persons have been registered with the National AIDS control Program (NACP)

  • 19%
  • f

the total estima mated cases.

  • 7,531

were

  • n

ART RT during the last six mo months hs

  • 2,009

(27%) were IDUs

  • 622

(8.2%) patients with TB

TB Screening in HIV + IDUs (Pilot done at Nai Zindagi site) Total Screened 902 902 AFB + 15 GeneXpert (MTB) 38 GeneXpert (Rifampicin Resistant) 2 Culture DST 31

Ref: Data presented in TB-HIV Coordination Committee Meeting in Dec-16

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SLIDE 10
  • HIV

infection among TB patients showed an estimated prevalence

  • f

0.42%

  • Varies

between sites,

  • Exposure

to risk factors

  • The

prevalence

  • f

TB in PLHIV estimated at 8.2%

  • Depends
  • n

status

  • f

their immunity level (CD4 counts) and

  • ther

risk factors

  • Data

limitations were

  • n

both sides, as segregation by age, gender, risk group identification etc is not available.

  • Guidelines

for management

  • f

TB-HIV Co-infection are available; but, needs to be updated

  • Capacity
  • f

the staff

  • n

both sides is inadequate

  • Linkages

between the two programs at various levels

  • f

implementation are not well- established, resulting in weak coordination between the two programs, especially at facility level.

  • Further

Conclusion

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SLIDE 11

Recommed ednations

  • The

problems

  • f

TB and HIV are enormous and a proper mechanism needs to be in place for effective management and advocacy at all levels

  • f

health care is needed

  • Improved

collaboration between TB and HIV/AIDS programs at all levels is the key for effective control

  • f

these infections

  • Further

studies and

  • perational

research are needed for in-depth analysis

  • f

the problem and find workable solutions

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SLIDE 12

Thanks nks