State of the Industry A view from the West David Thomas Director, - - PowerPoint PPT Presentation

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State of the Industry A view from the West David Thomas Director, - - PowerPoint PPT Presentation

State of the Industry A view from the West David Thomas Director, Industry Research & Analysis BIO BIO Europe Spring March 11, 2013 1 BIOTECHNOLOGY INDUSTRY ORGANIZATION PRESENTATION TITLE IN FOOTER MONTH XX, 2012 U.S. IPOs:


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BIOTECHNOLOGY INDUSTRY ORGANIZATION PRESENTATION TITLE IN FOOTER MONTH XX, 2012

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David Thomas

Director, Industry Research & Analysis BIO BIO Europe Spring March 11, 2013

State of the Industry

A view from the West

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U.S. IPOs: Returning to “Normal”?

Source: Factset, BIO Industry Analysis, March 6, 2013

Performance

Since IPO Date 2009 2010 2011 2012 2013 CLASS:

3 (3) 17 (12) 13 (8) 13 (11) 3 (2)

Total # (therapeutic #):

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1994 2000 2005 2010 2013

20 YEARS OF BIOTECH

(Nasdaq Biotechnology Index, NBI)

Source: Factset, BIO Industry Analysis, March 6, 2013

1580 1611

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Source: Factset, BIO Industry Analysis, March 6, 2013

Performance

Since IPO Date

Amount

Raised vs Filed 2009 2010 2011 2012 2013 CLASS:

U.S. IPOs: Returning to “Normal”?

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Fewer Pipeline Acquisitions

Pipeline Acquisitions $>10M

Source: BIO Industry Analysis, Elsevier Database, March 2013

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Fewer Pipeline Acquisitions

Pipeline Acquisitions $>10M Pipeline Alliances $>10M

Fewer Pipeline Alliances

Source: BIO Industry Analysis, Elsevier Database, March 2013

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Source: BIO Industry Analysis, Elsevier Database, February 2013

M&A: BIOBUCK Breakout in 2012!

Private Company Acquisitions >$10M

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Good news for VCs:

Expanding multiples on upfronts

Source: HBM Partners, January 2013

3.1 3.2 3.4 3.5 5.1 3.7 4.6 6.2 1.6 2.0 1.8 1.5 2.0 1.0 2.5 3.5

1 2 3 4 5 6 7

2005 2006 2007 2008 2009 2010 2011 2012

Multiple

Total Deal Value/Invested Capital Median Multiple on Upfront

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Time to Pharma Acquisition: Getting Longer and Longer

Source: HBM Partners, January 2013

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Venture: Pharma to the Rescue?

Source: BIO Industry Analysis, BioCentury’s BCIQ, March 2013

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Pharma VC backing: A Higher Step-Up at M&A

N=24 N=84 Average Step-Up at Acquisition

Source: Elsevier’s Start-Up, October 2012

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Breakouts Everywhere!

Source: BIO Industry Analysis, March 2013

  • Biotech Index
  • FDA Approvals
  • Orphan Indication Approvals
  • IPO performance
  • Big Earnout structures
  • Step-ups on VC acquisition exits
  • Corporate Venture Capital
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BIOTECHNOLOGY INDUSTRY ORGANIZATION PRESENTATION TITLE IN FOOTER MONTH XX, 2012

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