Signal Processing and Data Analysis 2005-2008 21 st July 2008 - - PowerPoint PPT Presentation

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Signal Processing and Data Analysis 2005-2008 21 st July 2008 - - PowerPoint PPT Presentation

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Signal Processing and Data Analysis 2005-2008 21 st July 2008 Members 2008 4 PhD, 3 PosDoc (2 - Cincia 2007) , 2 PhD Stud 2005 (PhD , FCUP ) , PI Ana Paula Rocha Argentina Leite (PhD stud , FCUP and UTAD ) (PhD stud FCT ,

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Signal Processing and Data Analysis

2005-2008

21st July 2008

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Members 2008

4 PhD, 3 PosDoc (2 - Ciência 2007), 2 PhD Stud

  • 2005

– Ana Paula Rocha (PhD, FCUP) , PI – Argentina Leite (PhD stud, FCUP and UTAD) – Sónia Gouveia (PhD stud FCT, European PhD) – Rute Almeida (PhD stud FCT, European PhD)

  • 2006

– Ana Rita Gaio (PhD, FCUP) – Rute Almeida

(European PhD concluded)

  • 2007

– Helena Brás Silva (PhD, IPP) –

  • J. Pinto da Costa

(PhD, FCUP) – Rute Almeida (Pos Doc CiberBBN, Zaragoza)

  • 2008 (May)

– Paulo Aguiar (Pos Doc Ciência 2007, CMUP) – Murilo Baptista (Pos Doc Ciência 2007, CMUP)

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  • Biomedical Signals and Systems

Case Study: cardiovascular signals analysis – Study of the ECG, multimodal cardiovascular variability and cardiorespiratory coupling – Time, frequency, time/scale (wavelets), linear and non linear analysis – Time variant modeling: Long-range / short term dependency in HRV (ARFIMA )

  • Statistical Modeling in the Health Sciences

Case Study: nutritional and rheumatic epidemiology – Classification techniques on continuous data: dietary patterns construction – Latent variable models: knowledge of rheumatic disease versus health status

  • Statistical Learning

– Classification of ordinal data. Graph theory based clustering. – Weighted measures in classification. Weighted PCA.

  • Bioinformatics/Biomathematics

– Computational Neuroscience – Information/synchronization in active networks. Complex systems analysis.

  • Scientific Consultancy (joint publications)

Research Lines

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Collaborations

  • Technical and Scientific

– Italy: Mortara Rangoni / Portugal,CardioSolutions – Spain: Univ Zaragoza, Communication technologies Group, Ciber BBN – UK: Univ Edinburgh, Institute for Adaptive and Neural Computation – USA/Brasil: Univ Illinois / Univ S. Paulo – Germany: Univ. Potsdam and Max Plank Institute PKS – Portugal: FEP, UP and UIMA, UA; INESC

  • Clinical and Experimental

– Belgium: Hospital Erasmus, Brussels – Portugal: FMUP and Hospital S. João (HSJ) Porto

  • SCIIP, Serviço de Cuidados Intensivos e Intermédios em Pediatria, HSJ
  • Laboratório de Sono, Serviço Pneumologia HSJ, Porto
  • Serviço de Higiene e Epidemiologia
  • Instituto Histologia e Embriologia

– Portugal: FFUP (Serviço de Tecnologia Farmacêutica e Serviço de Toxicologia) – Portugal: IBMC (Instituto de Biologia Molecular e Celular)

  • Grupo de Neurobiologia Básica e Clínica
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Achievements - Publications

  • 2005-2006

– 7 Papers in international peer reviewed Journals (ISI, IP Impact Factor 2006)

  • Neuroscience

IP=3.427

  • IEEE Transactions on Biomedical Engineering

IP=2.302

  • Physiological Measurement

IP=1.438

  • Medical and Biological Engineering and Computing

IP=1.018

  • Digital Signal Processing

IP=0.889

  • Biomedizinischie Technik

IP=0.835

  • Journal of Sensory Studies

IP=0.794

– 6 Papers in Proceedings of International Conferences (5 ISI Proceedings)

  • 2007-2008

– 8 Papers in international peer reviewed Journals

  • Journal of Machine Learning Research

IP=2.255

  • Neural Networks

IP=2.000

  • Ecotoxicology and Environmental Safety (in press)

IP= 2.000

  • Early Human Development

(2; 1 in press, on line) IP=1.738

  • Journal of Sensory Studies;

IP=0.794

  • Australian & New Zealand Journal of Statistics

IP=0.347

  • Cardiovascular & Haematological Disorders-Drug Targets

– 13 Papers in Proceedings of International Conferences

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  • 2005-2006

– PhD (3; 2 European Phd, 1 concluded)

  • Applied Mathematics (1 European Phd concluded 2006), AP Rocha

– MSc (3)

  • Computational Methods in Science and Engineering – 2005, AP Rocha
  • Statistics – 2005, AP Rocha
  • Mathematical Engineering - 2006, AR Gaio
  • 2007-2008

– PhD (5, 2 concluded, 1 European Phd ongoing)

  • Computer Science – 2 - 1 concluded 2007, J Pinto da Costa
  • Applied Mathematics - 2 - 1 waiting for Viva, 1 European Phd - AP Rocha
  • Public Health - 1- AR Gaio

– MSc (7, 3 concluded)

  • Bioinformatics -1 – concluded 2007, AP Rocha
  • Mathematical Engineering - 2 - concluded 2007, ARGaio / J.Pinto da Costa
  • Statistics -1 , J.Pinto da Costa
  • Mathematical Engineering -3, J.Pinto da Costa
  • Medical Physics -1, AP Rocha

Graduate StudentsTraining

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  • 2005-2006

Program: Scientific Research in Pre-Graduation. U Porto. – Distinction Award, March 2005, project

Diabetes Mellitus: Early signs in the pré-sintomatic phase of the autonomic disfunction Funding: Univ Porto / Fundação Ilídio Pinho. (1 student: FCUP) – Cardiovascular variability analysis in critical illness: follow-up and outcome. Funding: Univ Porto / Caixa Geral Depósitos (CGD). (9 students: 5 FCUP, 4 FMUP).

  • 2007-2008

Program: Scientific Research in Pre-Graduation. Pluridisciplinary Projects 2007. Funding: Univ Porto / CGD

  • Multimodal analysis in pediatric coma (4 students: 3 FCUP, 1 FMUP).
  • Arterial Blood Pressure responses and Heart Rate variability: role in the diagnosis and

prognosis of Sleep Disordered Breathing (2 students: FCUP).

  • 2008-2009

FCT Ciência 2008 BII (research integration of 5000 1st cicle students)

CMUP Call Posted EraCareers, July 2008

Pre-Graduate StudentsTraining

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  • 2005-2006

– Tachografic, Spectral and Fractal analysis of heart rate variability in pre and pos natal life. Application in medical diagnostics and educational systems.

Ref: POSI/CPS/40153/2001 (2002 – 2006). Funding: 55 000 € ( 21 628 € at FCUP ). Involved Institutions: FEUP/INEB (Coordination), FCUP, FMUP. CMUP Team: AP Rocha.

– Tratamiento de señal en el análisis del ECG y polisomnografía: Procesado

  • rientado por el modelado fisiológico.

Ref: CYCT/FEDER TEC2004-05263-C02-02, (Spain, 2004- 2007) . Funding: 123 200 €. Involved Institutions: Zaragoza Uiversity (Spain, Coordination), FCUP (Portugal), Univ. Zaragoza, Hospital Miguel Servet, Zaragoza (Spain), Lund University (Sweden), Favaloro University (Argentina), Saint George Hospital, London (UK), Nice University (France). CMUP Team: AP Rocha, RB Almeida

  • 2007-2010
  • Analisis multimodal-multicanal e interpretacion fisiológico diagnostica de señales

biomedicas del sistema cardiovascular, respiratorio autonomico y del sueño: variabilidad dynamica e interacciones

Ref: CYCT/FEDER - TEC2007-68076-C02-02(Spain, 2007- 2010). Funding 215 351 €. Extension of TEC2004-05263-C02-02. Innovation and links to foreign centers as Duke University Medical Center (USA), MIT (USA), Medtronics research center (Holland). CMUP Team: AP Rocha, S Gouveia, RB Almeida (Ciber BBN)

Networking/Research Projects

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  • Biomedical Signals and Systems

Cardiovascular signals analysis and risk stratification – Improved Multilead Wavelet ECG delineation and Cardiorespiratory coupling characterization. – Correntropy as complementary to time, frequency, time/scale, linear and non linear analysis. – Novel approaches in long-term and non stationary HRV modeling: volatility (ARFIMA-GARCH)

  • Statistical Modeling in the Health Sciences

Case Studies from epidemiology and public health – Classification techniques on ordinal data: dietary patterns construction – Latent mixture variable models: detection of cardiac failure

  • Statistical Learning

– Classification of ordinal data. Graph theory based clustering. – Weighted measures in classification. Weighted PCA.

  • Bioinformatics/Biomathematics

– Computational Neuroscience: neural connectivity/network architecture, activity level control in spiking networks, learning and memory models… – Information/synchronization in active networks. Complex systems analysis versus dynamic systems tools

  • Ciência2008 – Joint Call 2 Pos Doc Positions - Statistical Analysis and Applications

Research 2007-2010

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Case Study Biomedical Signals and Systems

Cardiovascular signals analysis and risk stratification

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Characterization in Ambulatory and Long term Follow-up and prognosis in Critical Care Bedside

ECG automatic delineation

using Wavelet methodologies

RR analysis / Heart Rate Variability ECG Variabilities interactions QT variability driven by RR

Beat-to-beat variability series 24 hours

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Multimodal analysis

for the characterization of the cardiovascular system

Sleep as a cardiovascular frontier Sleep apnea studies Goal: Understanding of the ANS Invasive and drug induced experiments

  • ECG and Arterial Blood Pressure
  • Thorax respiratory effort sensors
  • Nasal Flow Channels
  • Oxygen saturation
  • EEG, EOG, EMG, Body position sensors
  • ECG and Arterial Blood Pressure
  • Respiration
  • Muscular Sympathetic Neural Activity

Polissonography study