Rinderpest the state of play since eradication in May 2011 - PowerPoint PPT Presentation

Rinderpest the state of play since eradication in May 2011 BIOLOGICAL AND TOXINS WEAPONS CONVENTION (BWC) MEETING OF EXPERTS United Nations, Geneva. 4-8 August 2014 Dawid Visser Scientific and Technical Department World Organisation for Animal Health (OIE)

Since 2011… • May 2011 – 79 th OIE General Session, the OIE together with FAO declared global freedom from rinderpest OIE Resolution No 18 (2011) • May 2013 – new OIE Terrestrial Animal Health Code Chapter (8.14) on rinderpest adopted by Member Countries (MC) • OIE, MC to report annually about stocks of rinderpest virus containing material (RPVC) • MC obliged to report whether hold RPVC or not to cover for future discovery of virus stocks • OIE use surveillance data to monitor progress with destruction and sequestration of rinderpest globally

• OIE developed a secure web-based electronic reporting system (ERRS) • Nov 2013, OIE launched the ERRS in 3 official languages of the OIE, to 178 Member Countries • First survey on remaining stocks of rinderpest virus (RPV) containing material May 2014 – Results of the 1 st report officially verified • and adopted by the OIE General Assembly of Delegates

167/178 OIE Member Countries reported on RPV-containing material - 2013 144 Countries reported NO RPV 81% 180 Countries will be covered starting in May 2014

Results • OIE received reports from 94% (167/178) of Member Countries 86% (144/167) of countries reported not to hold any stocks of • RPV containing material • 14% (23/167) reported to hold RPV containing material 23 Countries holding RPVC in 28 different institutes • • 1 country reported to hold RPVC in 5 institutes • 1 country reported to hold RPVC in 2 institutes • 21 countries holding RPVC in 1 institute per country • 5 laboratories in 4/23 countries reported to have destroyed some form of RPV • 50% (14/28) of laboratories reported to hold some kind of live RPV 3/28 laboratories reported to hold 1 700 200 doses of • manufactured RP vaccine

Results continue... Current global distribution of RPV-containing material OIE - 2013 survey Number of Member 28 Institutes holding RPV/ OIE Region Countries in that Member Countries reported region (MC) Africa 52 8 /50 (16%) Americas 30 3 /29 (10%) Asia, Far East and Oceania 36 12 /32 (38%) Europe 53 6 /49 (12%) Middle East 20 2 /20 (10%)

Results continue... Questionnaire also requested information on bio-containment level of laboratories holding RPV-containing material • 1/28 facilities did not respond • 27/28 facilities reported on the bio-containment level BSL 4 BSL 3 BSL 2 3/28 15/28 9/28 11% 54% 32% � Annual OIE survey to follow each year to compare one year to the next

Rinderpest holding facilities Progress since May 2011 • OIE and FAO jointly established procedure to review applications • Procedure for approving rinderpest holding facilities and the mandate for such facilities • OIE General Session (May 2014) adopted Resolution No. 23 • FAO-OIE Rinderpest Joint Advisory Committee reviewed applications from 5 institutes in 4 countries for RPV – holding facilities • Next step in approval process – Expert team site inspection of facility First Expert team to visit facility in 3 rd quarter 2014 • • Interim – until OIE & FAO have approved RPV-holding facilities MC advised to use existing OIE Reference Laboratories for rinderpest sequestration

Number of applications OIE Region received Africa 1 Americas 1 Europe 1 Asia, Far East and Oceania 2 (same country) Middle East 0

Research: Involving manipulation of RPV containing material Since 2011 the OIE and FAO approved 2 applications for research 1. Study to assess whether peste des pestits ruminants (PPR) vaccines can protect against rinderpest virus infection (project funded by the OIE- 1 st phase begun Oct 2013 and 2 nd phase due for Jan 2015) 2. Sequencing and destruction of historical rinderpest isolates (project not yet funded)

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