Rinderpest the state of play since eradication in May 2011 - - PowerPoint PPT Presentation

BIOLOGICAL AND TOXINS WEAPONS CONVENTION (BWC) MEETING OF EXPERTS United Nations, Geneva. 4-8 August 2014

Rinderpest

the state of play since eradication in May 2011

Dawid Visser Scientific and Technical Department World Organisation for Animal Health (OIE)

Since 2011…

• May 2011 – 79th OIE General Session, the OIE together with

FAO declared global freedom from rinderpest OIE Resolution

No 18 (2011)

• May 2013 – new OIE Terrestrial Animal Health Code Chapter

(8.14) on rinderpest adopted by Member Countries (MC)

• OIE, MC to report annually about stocks of rinderpest

virus containing material (RPVC)

• MC obliged to report whether hold RPVC or not to cover

for future discovery of virus stocks

• OIE use surveillance data to monitor progress with

destruction and sequestration of rinderpest globally

• OIE developed a secure web-based electronic reporting

system (ERRS)

• Nov 2013, OIE launched the ERRS in 3 official languages
• f the OIE, to 178 Member Countries
• First survey on remaining stocks of rinderpest virus

(RPV) containing material

• May 2014 – Results of the 1st report officially verified

and adopted by the OIE General Assembly of Delegates

144 Countries reported NO RPV 81%

167/178 OIE Member Countries

reported on RPV-containing material - 2013

180 Countries will be covered starting in May 2014

Results

• OIE received reports from 94% (167/178) of Member Countries
• 86% (144/167) of countries reported not to hold any stocks of

RPV containing material

• 14% (23/167) reported to hold RPV containing material
• 23 Countries holding RPVC in 28 different institutes
• 1 country reported to hold RPVC in 5 institutes
• 1 country reported to hold RPVC in 2 institutes
• 21 countries holding RPVC in 1 institute per country
• 5 laboratories in 4/23 countries reported to have destroyed some form of RPV
• 50% (14/28) of laboratories reported to hold some kind of

live RPV

• 3/28 laboratories reported to hold 1 700 200 doses of

manufactured RP vaccine

Results continue...

Current global distribution of RPV-containing material OIE - 2013 survey

OIE Region Number of Member Countries in that region (MC) 28 Institutes holding RPV/ Member Countries reported Africa 52 8/50 (16%) Americas 30 3/29 (10%) Asia, Far East and Oceania 36 12/32 (38%) Europe 53 6/49 (12%) Middle East 20 2/20 (10%)

Results continue...

Questionnaire also requested information on bio-containment level of laboratories holding RPV-containing material

• 1/28 facilities did not respond
• 27/28 facilities reported on the bio-containment level

Annual OIE survey to follow each year to compare one year to the next

BSL 4 BSL 3 BSL 2 3/28 15/28 9/28 11% 54% 32%

Rinderpest holding facilities

Progress since May 2011

• OIE and FAO jointly established procedure to review applications
• Procedure for approving rinderpest holding facilities and the mandate

for such facilities

• OIE General Session (May 2014) adopted Resolution No. 23
• FAO-OIE Rinderpest Joint Advisory Committee reviewed

applications from 5 institutes in 4 countries for RPV – holding facilities

• Next step in approval process – Expert team site inspection of

facility

• First Expert team to visit facility in 3rd quarter 2014
• Interim – until OIE & FAO have approved RPV-holding facilities

MC advised to use existing OIE Reference Laboratories for rinderpest sequestration

OIE Region Number of applications received Africa 1 Americas 1 Europe 1 Asia, Far East and Oceania 2 (same country) Middle East

Research:

Involving manipulation of RPV containing material Since 2011 the OIE and FAO approved 2 applications for research

• 1. Study to assess whether peste des pestits ruminants (PPR) vaccines can

protect against rinderpest virus infection (project funded by the OIE- 1st phase begun Oct 2013 and 2nd phase due for Jan 2015)

• 2. Sequencing and destruction of historical rinderpest isolates

(project not yet funded)

Thank you for your attention