Research : a neccessity Research : a neccessity D A il J i Dr Anil - - PowerPoint PPT Presentation

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Research : a neccessity Research : a neccessity D A il J i Dr Anil - - PowerPoint PPT Presentation

Research : a neccessity Research : a neccessity D A il J i Dr Anil Jain Professor of Orthopaedics University College of Medical U i it C ll f M di l Sciences, D lhi Delhi & Edit Editor Indian Journal of Orthopaedics


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Research : a neccessity Research : a neccessity

D A il J i Dr Anil Jain

Professor of Orthopaedics U i it C ll f M di l University College of Medical Sciences, D lhi Delhi & Edit Editor Indian Journal of Orthopaedics

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Practice of Medicine

It is an art Transformed from an art based on “belief in

l f ” “ b d ” supernatural force” to “ art based on science”

This art is learnt by “observations of talented

h i i d b i physicians and by practice.

to documented evidence and than on validated

evidence.

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Art/ science ratio /

More and more knowledge based on scientific research For diagnosis For treatment and For prevention of the disease Will reduce guess work to achieve pt care.

Will reduce guess work to achieve pt care.

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Modern medicine

Chinese medicine

Ayurveda

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Ayurveda y

Evolved from ongoing body of practical

medical experience passed down orally h h i il through numerous generations until, eventually, it was written down.

Sushruta‐samhita ‐ 1st century BCE, Charaka‐samhita ‐ 1st century A.D.

y

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Ayurveda y

Ayurveda ‐ far ahead of Western medicine in surgery Based upon a combination of empirical treatments. erroneous religious and philosophical

erroneous religious and philosophical assumptions

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Modern medicine

like Ayurveda,

E l d f l i ifi f

Evolved from a long pre‐scientific stage of

development,

applied proper scientific principles

  • ld ideas ‐‐‐‐ simply superstitious , with no genuine

medical foundation. ‐‐‐‐‐ Discarded

  • kept the things that worked and

This is something that Ayurveda never did;

g y

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Ayurveda v/s modern medicine y /

Ayurveda remains in its original

pre‐scientific stage,

Western scientific medicine Western scientific medicine

advanced

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Medicine means Western medicine Rest of them are alternative medicine

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Medical science has to evolve Medical science has to evolve

d b l

Because medicine is a biologic science Biology is not stationary

Biology is not stationary

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Asia pacific region p g

Unique

R i f

Region of contrasts Highly developed to poorest of poor Excellent health infrastructure to no infrastructure

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Low income group – GNI 995 US $ g p $

Bangladesh, Myanmar, ‐population 213 million

I di P ki Vi N h K j d

India, Pakistan, Vietnam, North Korea – just entered

in lower middle income countries

Total population‐ 1773 million 43.4 %of total 4086 million

43 4

World population – 6900 million

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Lower middle income countries

GNI ‐ US$996 and US$3,945 Sri Lanka Philippines Indonesia 561 millions Sri Lanka, Philippines, Indonesia ‐ 561 millions

Chi

GNI 8 US

China –GNI 4382 US $

Just entered in upper middle income countries Population‐ 1337 million Total population – 1705 out of world 6900 million

Total population 1705 out of world 6900 million

43 % of 4086 million

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Upper middle income countries pp

US$3,946 and US$12,195 Malaysia , Thailand ,Turkey Population 170 millions

4% of 4086 millions

World population – 6900 million

World population 6900 million

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High income countries g

GNI above US$11,906.

A li H K N Z l d T i

Australia, Hong Kong, New Zealand , Taiwan ,

Singapore, South Korea , Japan

Population‐ 438 million

Population 438 million

10.7% of 4086 millions

7

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Summary y

AP region ‐ 4086 millions ‐‐‐World – 6900 million LIC and Low middle income countries (87% or

LIC and Low middle income countries (87% or

APOA countries and 50% of world population

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SLIDE 17

How science grows ? g

Should have problem Identify the cause Plan the strategy to solve Plan the strategy to solve Scientific appraisal of outcome Longitudinal collection of evidence D fi it

id

Definite evidence Evidence should be retrievable beyond

y the human life

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Why do we need research???? y

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Modern Medicine ( Orthopaedics)

Practices are guided by the west . Whatever advocated followed in principle and

f ll practice successfully

Reason – there was not much disimilarity in

di fil 6 disease profile 60 yrs ago.

NOW Huge disparity

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High income countries

W ll i d h lth i

Well organised health services Infective , nutritional disease ‐

Infective , nutritional disease eliminated

Systematic documentation Effective insurance system Effective insurance system High doctor : pt ratio – 2.56 per 1000

g docto : pt at o .56 pe 000

Bed : Pt ‐ 33 per 10000

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Health services in LIC

Travel 50‐100 km for basic health services

P id l i

Provide elementary services No financial resource to reach bigger city hospital Hence treated by osteopaths or non‐specialist We get all complicated cases Minimum standard of care not assured

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Problems LIC ‐ poor Problems LIC poor infrastructure

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Huge n/o patients g / p

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Di fil Disease profile

Fresh fractures Neglected fractures

g

Complication of

treatment treatment

All

t f

All spectrum of

clinical cases in plent plenty

Natural history of

di disease

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Pt’s load in india and developing countries

Health services – urban based Population rural based Population rural based

R l l i

Urban based health services

Rural poulation

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LIC and MIC – public sector p

Tremendous intellectual capacity Lack “state of art” infrastructure ‐

l d

Heavy pt load Poor record keeping

f ll

Poor follow up Migratory population No hospital specific – clinical work

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Pvt sector‐ corporate hospitals t secto co po ate osp ta s

State of art technology

Li i d li i l k i l d f

Limited clinical work – in volume and spectrum of

disease N li b b i li

Not generalist but sub‐speciality experts

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Best services ‐‐ Quantum of Best services Quantum of workload v/s work force /

We should know Burden of musculoskeletal disease and trauma in Burden of musculoskeletal disease and trauma in

total and in specific geographic area.

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We do not have data

Not even planning to have data. No disaster plans

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Scenario for training in Scenario for training in Orthopaedics p

Books written by western authors

  • n their needs

Campbell’s operative Orthopaedics –

TB is just mentioned and PPRP removed TB is just mentioned and PPRP removed

Neglected trauma – just mentioned

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Evidence based clinical treatment

Generate evidence

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High income countries g

They can generate evidence for

ey ca ge e ate ev de ce o themselves

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Low and middle income countries

Very little research input

Wh ill f f

Who will generate for most of our

clinical problems and of 2/3 world p /3

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Clubfeet

Th d l i t i th Natural history of disease The developing countries see the natural history of disease

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MRC has done lots of work MRC has done lots of work

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NOW they have no reason to

y work on TB spine – infection is l t li i t d almost eliminated

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Can we generate evidence ? g

We have clinical problem at hand

W h i ll l i

We have intellectual capacity We have technical know how What needs to be added ‐‐ will to do Infrastructural support

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N d f th t diff t SACH f t / j i f t Need of the pt different. SACH foot v/s jaipur foot

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How much are we contributing to How much are we contributing to the literature??

JBJS B

JBJS Br ‐ 2010

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Publications

Total – 66 of over 300 less than 20% of total world contributions less than 20% of total world contributions Over 75% population contributes less than 20 % Low income ‐ 0 ( 15 ,India‐9, North korea ‐6 ) – 30% Lower middle –0 ( 8 china)‐ 12% Upper middle‐ 4 ‐ 6% Upper middle‐ 4 ‐ 6% High –39 –

60%

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Research

Transform biological discovery to medical treatment

Health research

Government d Industry Research institutes

Health care Health care

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Requirements to conduct research q

Research temper Research temper Funding I f

t t

Infrastructure Balance between Service and research

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Is current clinical community Is current clinical community poised to do that? p

NO

How can we inculcate scientific temper and have a How can we inculcate scientific temper and have a

regular bench of clinician scientist

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Barriers to research

Stimulate faculty for research Improve research funding Provide institutional support for research Give extra credit for performers Give extra credit for performers Give extra credits for researchers over non

researchers researchers

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Infrastructure

Scarce funding – private

‐ Government

Private funding – clinical trials in development

phase for market approval

For patient benefit research – a big no

For patient benefit research a big no

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Govt investment in research

  • Govt. investment in research

UNESCO recommonds‐ 2% of GDP for growth and

d l t development

US and Japan – 2.8% Canada‐ 1.5% India ‐ .8%

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Hospital infrastructure p

No research cell

ll f l b h l

Ancillary facilities‐ biostat . Ethical committee

protocols

Time allocation for research Access to information

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Access to information

Literature support –poor

pp p

Journals not available, Most of journals cost heavy Most of journals cost heavy Very few open access

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Research topics p

No exotic topics

T i i hi hi h f d

Topic is something – which we face everyday Because‐‐‐ You can bring out something new on what you see

most

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What needs to be done???

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h h ld d ??? What should we do ???

Know the burden of Know the burden of

disease

Pt load

minimum basic health

services.

Pt load

h h l

Cover the whole

population. p p

Health services

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We must do

Define regional needs

C i i f h ’ l

Creating an environment for research‐ can’t leave to

individual clinician’s preference H l i i b i h

Help in overcoming barriers to research Guidance to conduct research Need based teaching curriculum Avenue for publications Rewarding clinician‐scientist

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APOA

Co‐ordinate credible need based research

Id if i i i i h d i f d

Identify institutions ‐ with good infrastructure and

technical knowhow – such as India, China, Pakistan ‐ We have both worlds and personnels to do that We have both worlds and personnels to do that

In house training

G i f i LIC d MIC

Grooming future mentors in LIC and MIC Because we match developing and developed nations

l l bl in clinical problems

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Th t f d Than a step forward

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Do it for your problems Do it for others Because we can generate evidence for developed

nations.

Living biology is our strength We should use it for alleviating pains of suffering

g g humanity

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Objective of this meeting or such Objective of this meeting or such efforts ‐‐

To bring about a change in mindset

R h i hi b i f i i l ll

Research is nothing but a summation of a critical well

thought of conclusions about the outcome of treatment we offer to the patients everyday treatment we offer to the patients everyday.

And

W ll h h f i i d k

Well thought of innovations we undertake Which we were doing since time immemorial Only change now ,wish to do at a faster pace Ensuring it is retrievable beyond human life

g y

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Thank you very much for patient Thank you very much for patient hearing

Together only we can minimize and if not Together only we can minimize and if not eliminate the pain and disability from the world

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Objective

Advance the science and art of Orthopaedics Advance the science and art of Orthopaedics and traumatology to serve humanity H thi t ti Hence,this presentation

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Could we prevent this We need to diagnose

before a deformity before a deformity develops W h h i

We have to treat them in

numbers

By meagre resources in

h i these countries

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Asia pacific Orthopaedic Asia pacific Orthopaedic Association

Nineteen Member Chapters.

A li B l d h Chi H K I di

Australia, Bangladesh, China, Hong Kong, India,

Indonesia, Japan, Korea, Malaysia, Myanmar, New Zealand Pakistan Philippines Singapore Taiwan Zealand, Pakistan, Philippines, Singapore, Taiwan, Thailand, Vietnam Turkey and Sri Lanka.

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Asia pacific Orthopaedic Asia pacific Orthopaedic Association

Nineteen Member Chapters.

A li B l d h Chi H K I di

Australia, Bangladesh, China, Hong Kong, India,

Indonesia, Japan, Korea, Malaysia, Myanmar, New Zealand Pakistan Philippines Singapore Taiwan Zealand, Pakistan, Philippines, Singapore, Taiwan, Thailand, Vietnam Turkey and Sri Lanka.

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Definition of income groups g p

Low income countries had GNI per capita of US$995

  • r less
  • r less.

Lower middle income countries had GNI per capita

between US$996 and US$3 945 between US$996 and US$3,945.

Upper middle income countries had GNI per capita

between US$3 946 and US$12 195 between US$3,946 and US$12,195.

High income countries had GNI above US$11,906.