Practical lesson Two models of the cardiovascular system: 1. - - PDF document
Lesson 5 University of Bergamo Engineering and Management for Health FOR CHRONIC DISEASES MEDICAL SUPPORT SYSTEMS LESSON 5 Lumped parameter models of the cardiovascular system: practical lesson. Ettore Lanzarone March 25, 2020 Practical
Ettore Lanzarone March 25, 2020
Two models of the cardiovascular system: 1. Simple RLRC model 2. Accurate model with several segments (Burattini and Gnudi, 1982; Lanzarone et al., 2017)
Simple RLRC model
Simple RLRC model
Accurate model with several segments
Lanzarone et al. (2017)
Lanzarone et al. (2017)
Accurate model with several segments
PRINCIPALE.T Macro to run the system Centrale.T Perif***.T Segments and peripheral networks Conness.T Exchange of variables between subsystems
Accurate model with several segments 1. Open MTESI 2. Write MTESI in the command dialog box 3. Launch simulation with the dedicated window (store variables of interest and use fixed step time) 4. Write “Ashow” and “Show” to view results
Accurate model with several segments Where to change parameters for the analysis we are conducting? File Centrale.T
1. Choose a duration of the simulation to be sure that the initial transient time is over 2. Compare the two models. Which is the most accurate one and why? 3. Evaluate the pressure in the aortic segments 2 – 7 in the complete
literature?
4. Study a pathological case: old patient with rigid vessels. All compliances reduced by a fixed percentage. What do you
5. Study a surgical case: insertion of an aortic prosthesis. Resistances are increased and compliances are decreased in segments 3 – 7
Based on the available information on the existing prostheses, chose the best one in order to limit the impact on pressure alteration.