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PHYSICS OF BIOLOGICAL SYSTEMS ph549 LECTURE 9 Energy and - PowerPoint PPT Presentation

PHYSICS OF BIOLOGICAL SYSTEMS ph549 LECTURE 9 Energy and Equilibrium LIFE and ENERGY Electromagnetic Energy Chemical Energy Mechanical Energy Thermal Energy Equilibrium and Non-equilibrium Equilibrium and Non-equilibrium Rob Philips,


  1. PHYSICS OF BIOLOGICAL SYSTEMS – ph549 LECTURE 9 – Energy and Equilibrium

  2. LIFE and ENERGY Electromagnetic Energy Chemical Energy Mechanical Energy Thermal Energy

  3. Equilibrium and Non-equilibrium

  4. Equilibrium and Non-equilibrium Rob Philips, Physical Biology of the Cell

  5. Free Energy Minimization Folding of proteins into the native state

  6. Free Energy Minimization Labro et. Al. Frontiers Pharmacology (2012) Gating of Ion Channels

  7. Free Energy Minimization Lim et. al. PNAS, 99, 16766 (2002) Shapes of red blood cells

  8. The Entropic dance F = E - TS Bo Peng (UMass Amherst)

  9. Binding of RNA Polymerase

  10. Binding of RNA Polymerase

  11. Binding of RNA Polymerase

  12. LIGAND Receptor Binding Barakat et. al. Recept. Clinic Invest. (2015) Haemoglobin

  13. LIGAND Receptor Binding

  14. LIGAND Receptor Binding Cairo et. al. Princ. Pharma (2012)

  15. Translation and Transcription

  16. Binding of RNA Polymerase

  17. Origins of Hydrophobicity

  18. References and further reading  Physical Biology of the Cell – Rob Phillips et. al. Chapters 5 and 6  Biological Physics – Energy, Information, Life – Phil Nelson Chapter 6

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