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PHYSICS OF BIOLOGICAL SYSTEMS ph549 LECTURE 9 Energy and - - PowerPoint PPT Presentation
PHYSICS OF BIOLOGICAL SYSTEMS ph549 LECTURE 9 Energy and - - PowerPoint PPT Presentation
PHYSICS OF BIOLOGICAL SYSTEMS ph549 LECTURE 9 Energy and Equilibrium LIFE and ENERGY Electromagnetic Energy Chemical Energy Mechanical Energy Thermal Energy Equilibrium and Non-equilibrium Equilibrium and Non-equilibrium Rob Philips,
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Equilibrium and Non-equilibrium
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Equilibrium and Non-equilibrium
Rob Philips, Physical Biology of the Cell
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Free Energy Minimization
Folding of proteins into the native state
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Free Energy Minimization
Gating of Ion Channels
Labro et. Al. Frontiers Pharmacology (2012)
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Free Energy Minimization
Shapes of red blood cells
Lim et. al. PNAS, 99, 16766 (2002)
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The Entropic dance F = E - TS
Bo Peng (UMass Amherst)
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Binding of RNA Polymerase
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Binding of RNA Polymerase
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Binding of RNA Polymerase
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LIGAND Receptor Binding
Barakat et. al. Recept. Clinic Invest. (2015)
Haemoglobin
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LIGAND Receptor Binding
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LIGAND Receptor Binding
Cairo et. al. Princ. Pharma (2012)
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Translation and Transcription
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Binding of RNA Polymerase
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Origins of Hydrophobicity
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References and further reading
- Physical Biology of the Cell – Rob Phillips et. al.
Chapters 5 and 6
- Biological Physics – Energy, Information, Life – Phil Nelson
Chapter 6