PAOLA-1 STUDY Platine, Avastin and OLAparib in 1 st line of advanced - - PowerPoint PPT Presentation

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PAOLA-1 STUDY Platine, Avastin and OLAparib in 1 st line of advanced - - PowerPoint PPT Presentation

PAOLA-1 STUDY Platine, Avastin and OLAparib in 1 st line of advanced high grade epithelial ovarian, fallopian tube, or primary peritoneal cancer. Randomized, Double-Blind, Phase III Trial of Olaparib vs. Placebo in Patients with Advanced FIGO


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PAOLA-1 STUDY

Platine, Avastin and OLAparib in 1st line of advanced high grade epithelial ovarian, fallopian tube, or primary peritoneal cancer.

Randomized, Double-Blind, Phase III Trial of Olaparib vs. Placebo in Patients with Advanced FIGO Stage IIIB – IV High Grade Serous or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer treated with standard First-Line Treatment, Combining Platinum-Taxane Chemotherapy and Bevacizumab Concurrent with Chemotherapy and in Maintenance.

Principal Investigator: Pr Isabelle Ray-Coquard, MD Centre Léon BERARD, Lyon, France

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PAOLA -1 Study design

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Recruitment status_13/05/2016

454 registered patients including :

  • 166 randomized patients
  • 103 screened failure