Oral Microbiome A secret garden with a rabbit hole Dr Frederik - - PowerPoint PPT Presentation

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Oral Microbiome A secret garden with a rabbit hole Dr Frederik - - PowerPoint PPT Presentation

Dec 13, 2023 363 likes •1.43k views

Oral Microbiome A secret garden with a rabbit hole Dr Frederik Martin Timmermans BDS MSC PICTON DENTAL SPA 1982 graduation Uni Utrecht NL BDS MSC Specific training in periodontal surgery 1983 first in Rotterdam to do amalgam replacement 1984

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Oral Microbiome

A secret garden with a rabbit hole

Dr Frederik Martin Timmermans BDS MSC

PICTON DENTAL SPA

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1982 graduation Uni Utrecht NL BDS MSC Specific training in periodontal surgery 1983 first in Rotterdam to do amalgam replacement 1984 postgrad prosthodontics & implant surgery 1987 implant surgery implemented in clinic 1992 setting up peer studygroup dentistry 1995 Uni A’dam training psycho analysis 2000 training Tera Mai Reiki 2003 -2007 board of advisors Dutch Dental Assoc. 2007 moved to Picton New Zealand 2008 Picton Dental Spa clinic

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In the beginner's mind there are many possibilities, but in the expert’s there are few - Shunryu Suzuki

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SPA DENTISTRY Sound & Music Back massage in dental chair Therapeutic hot stone Oxygen Therapies Safe Amalgam Removal Micro Current Therapy

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Senior dentistry = complex

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ECLECTIC DENTISTRY SKILLSETS

COMPASSION & REASSURING FEAR, STRESS, ANXIETY COMMUNICATOR WITH TEAM & MEDICAL FIELD ARTIST TO CREATE NATURAL SMILES RADIOLOGY X-RAYS AND CT ANESTHESIOLOGIST INCLUDING CPR SURGEON PERIO AND IMPLANTS PROSTHODONTIC SKILLS FOR RESTORING TECHNIQUES

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Mentoring Program for Integrative Senior Dentistry

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“combines the best of conventional western medicine with evidence-based complementary medicine and therapies”

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Using evidence - based reductionism to convince Holistic healing is working…?

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How reliable is evidence based research?

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Both editors in chief of the Lancet and the New England Journal of Medicine: at least 50% of published medical research is false!

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WHAT IS THE 50 % GOOD RESEARCH? WHAT IS THE MAINSTREAM MATRIX? FOLLOW THE MONEY?

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Biotech is BIG BIG business Agri - Food - Cosmetics Pharmaceuticals - Implants One newly developed chemical every 3 seconds!

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👅SALIVA TONGUE CHEEK 👅TEETH BIOFILM 👅RESTORATION BIOFILM 👅ENDODONTIC INFECTION 👅PERIODONTAL DYSBIOSIS 👅MICROBIAL PARADIGM SHIFT

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SALIVA TONGUE CHEEK BIOFILM

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Xerostomia

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500 prescription pharmaceuticals cause xerostomia

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  • Atropine and Scopolamine
  • Antidepressants
  • Antihypertensives
  • Phenothiazines
  • Antihistamines
  • Anti-Reflux Drugs (Proton

Pump Inhibitors)

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  • Retinoids
  • Bupropion
  • Protease Inhibitors
  • Opioids
  • Cannabinoids
  • Cytotoxic Drugs
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  • Didanosine
  • Diuretics
  • Ephedrine
  • Benzodiazepines
  • Interleukin-2
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Picture caries dry mouth

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Mouthbreathing Snoring

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Nose passage Pillows Buteyko method Anti snore devices Night guard

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Geo tongue Fissured tongue

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Candida

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Warning sign for dysbyosis Antibiotics and or sugar diet

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Simple tips

For dry mouth

Drink more (frequent) water or tea Reduce sugary food & drinks Check nose passage & snoring Frequent preventative dentistry Can include varnish / nightguard Please reduce medication causing it

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TEETH MICROBIOME

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Anton 200 x Surgical stereo 20 x S.E.M. up to 1,000.000x

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CARIES

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Diet is essential Simple carbohydrates grow biofilm much faster HERE Frequency is important

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Grazing bottle Sucking “Empty Energy” drinks

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Balanced occlusion articulation

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Oral hygiene has low influence

  • n prevention of caries,

frequency is less important than quality (better one long daily clean including interdental)

Cochrane review

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AUCH

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The administration of penicillin does NOT significantly reduce the pain perception or the quantity of pain medication required by people with irreversible pulpitis

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There is no study done ever to justify consequent systemic antibiotic use

  • n adults with painful apical

periodontitis or acute apical abscess

Dental antibiotic prescription accounts for 10 to 15 percent of all antibiotic use

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My Simple Tips

For really bad toothache

ADVISE DENTISTRY IS NECESSARY AND MORE GENTLE NOWADAYS ADVISE WINZ OR HOSPITAL CAN HELP WHEN C S CARD ADVISE RINSE WARM SALT WATER COLD COMPRESS FOR SWELLING RUB CLOVE OIL ON GUM, CURCUMINIOIDS CAN HELP PRESCRIBE IBUPROFEN MAX DAILY DOSAGE AND PARACETAMOL MAX DAILY DOSAGE, TAKE INTERMITTENTLY; (prednisolon 40 mg?)

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Exceptionial Antibiotics

WHEN?

1 CELLULITIC INFECTION (LOTS OF SWELLING USUALLY MANDIBULAR INCLUDING INCREASED TEMPERATURE, LYMPHADENITIS) CELLULITIC PATIENTS CAN BEST GO TO HOSPITAL CARE 2 IMMUNE COMPROMISED PATIENTS?

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Resist prescribing opioids Allegedly the opioid addiction epidemic has a frequent origin from prescription for dental issues… defensive medicine?

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RESTORATION BIOFILM

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Amalgam filling induced Oral Lichen Planus >2004 study NL: all patients who had amalgam replaced by composite fillings healed

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Composite surface roughness

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White fillings are all slightly cytotoxic It is concerning that minimal research is done on cytotoxicity of dental materials. One material has been tested non toxic: PEX, crosslinked poly-ethylene.

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Rough Oral Implant Surfaces

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ENDODONTIC INFECTION

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What if I could tell you that 98% of women who have breastcancer have a rootcanal on the same side of the mouth

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Suppose I would tell you that x % women with a wedding ring Have a rootcanal on the same side of the mouth?

Is this a correlation or causation?

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Marriage is bad for your teeth?

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Are there Alternatives To rootcanal treatment?

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Cone Beam CT scan

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Lesion Sterilisation Tissue Repair

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Prof. Edsuro Hoshino

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Pharmaceutical compounding made fresh every day

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Caries in pulpal dentin remains under dressing Filling Material

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Clinical and Radiological success of Lesion Sterilization and Tissue Repair with 3MIX-MP Antibiotic paste in a high age group. A retrospective

  • bservational study

Fred M. Timmermans BDS MSC , Lindsay Carlier BDS MSC NO CONFLICT OF INTEREST, NO SPONSOR, JUST CURIOSITY

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237 patients followed over minimal 24 months to 48 months

  • Av. age 57.6 yrs ranging 19 till 89 years

Overall clinical success (symptom free) 71.3 % Radiological success 49.4% Single rooted teeth had higher success than molars

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At our clinic we now nearly only do LSTR treatments for pulp infections. We are now on a quest for replacing antibiotics with essential oils

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SLIDE 80 J Dent Res. 2019 Jan;98(1):27-35. doi: 10.1177/0022034518808754. Epub 2018 Oct 29.

Pulp Stem Cell-Mediated Functional Pulp Regeneration.

Sui B1,2, Chen C2, Kou X2,3, Li B1, Xuan K1, Shi S2,3, Jin Y1. Author information 1 1 State Key Laboratory of Military Stomatology, Center for Tissue Engineering, School of Stomatology, Fourth Military Medical University, Xi'an, China. 2 2 Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA. 3 3 Guanghua School of Stomatology, South China Center of Craniofacial Stem Cell Research, Sun Yat-sen University, Guangzhou, China.
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PERIODONTAL DYSBIOSIS

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scurvy

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New Zealand has junkfood vit C deficiencies causing subclinical and clinical scurvy

  • 1. Dachs G, Munn D, Carr A, et al. Consumption of vitamin C is

below recommended daily intake in many cancer patients and healthy volunteers in Christchurch. N Z Med J. 2014; 127:73– 6.

  • 2. Carr A, Vissers M, Lewis J, Elder P. Multiple nutrient

insufficiencies--hypovitaminosis D and C in young adult New Zealand males. N Z Med J. 2012; 125:119–20.

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Porphyromonas Gingivalis is keystone pathogen while it can weaken the immune response through communication with cells

Biomed J. 2016 Aug;39(4):251-260. doi: 10.1016/j.bj.2016.08.003. Epub 2016 Sep 24.

Purinergic signaling during Porphyromonas gingivalis infection.

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Dysbiosis oral microbiome

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Manuka Honey & Oxygen

The effects of manuka honey

  • n plaque and gingivitis: a pilot
  • study. 2004
Source: PubMed

Periodontal Application of Manuka Honey: Antimicrobial and Demineralising Effects In Vitro

2017 Honey - a potential agent against Porphyromonas gingivalis: an in vitro

  • study. 2014
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Professional Ultrasonic scaling removes 99% of biofilm

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At home: Start one organic garden outside and one in your mouth Sprayfree!

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Get the right garden tools: 1: weedeater 2: hand weeder

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My Simple Tips:

Stop flossing! It’s traumatising! 2 minutes Oral B elec brushing 30 seconds wood stick treatment Once a day when healthy or Twice a day when bleeding

For oral hygiene

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MICRO BIOTA PARADIGM SHIFT

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Diet is better than brushing

The impact of the stone age diet on gingival conditions in the absence of oral hygiene.

Baumgartner S, et al. J Periodontol. 2009. Show full citation Abstract BACKGROUND: The objective of this study was to assess the oral microbiota and clinical data in subjects without access to traditional oral hygiene methods and who ate a diet available in the Stone Age. METHODS: Ten subjects living in an environment replicating the Stone Age for 4 weeks were enrolled in this study. Bleeding on probingSG (BOP), gingival and plaque indices, and probing depth (PD) were assessed at baseline and at 4 weeks. Microbiologic samples were collected at the mesio-buccal subgingival aspects of all teeth and from the dorsum of the tongue and were processed by checkerboard DNA-DNA hybridization methods. RESULTS: No subject had periodontitis. Mean BOP decreased from 34.8% to 12.6% (P <0.001). Mean gingival index scores changed from 0.38 to 0.43 (not statistically significant) and mean plaque scores increased from 0.68 to 1.47 (P <0.001). PD at sites of subgingival sampling decreased (mean difference: 0.2 mm; P <0.001). At week 4, the total
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Good food

So easy is it. Or not?

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SUGAR IS THE NEW TOBACCO Cristin Kearns

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INDUSTRY MANIPULATION OF RESEARCH

  • 1. Form your own research organisations
  • 2. Fund / create research to support position
  • 3. Cultivate relationships with policymakers
  • 4. Direct influence policymakers on dietary

guidelines and food labeling

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The threat is being described by WHO insiders as tantamount to blackmail and worse than any pressure exerted by the tobacco lobby.

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In New Zealand we consume

1.2 million dollar

in soft drinks per year

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MY VISION Growing consciousness health - mind - body - food connections in NZ dentistry

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Dentistry has the unique

  • pportunity to see

people on a regular

  • basis. We should use this
  • pportunity to expand

health consciousness and educate primal food

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  • WE. HERE. NOW.

ARE THE CHANGE WE WISH IN THIS CRAZY BEAUTIFUL WORLD

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Thank you Aroha Nui (Big Love)

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Thank you Aroha Nui (Big Love)