nutrient deficiencies in upper gastro-intestinal cancer patients - PowerPoint PPT Presentation

The prevalence of micro- nutrient deficiencies in upper gastro-intestinal cancer patients after treatment with surgery and chemotherapy Stephanie Wakefield – Upper GI Dietitian

Micronutrients • Fat malabsorption – vitamins A,D,E • pH changes – iron, vitamin B1, B12, folic acid • Free radicals – vitamins A & E • Duodenal bypass, bacterial overgrowth, decreased transit time, reduced IF, impaired pancreatic secretion • Previous studies include small patient numbers and are dated

Methodology • Invite all cancer-free post-surgery patients • Single visit study linked in with OPA • Blood sample and interview to assess: alcohol intake, smoking habit, bowel function, pancreatic enzyme therapy, multivitamin, B12 injection, PPI, iron supplementation • Gender, age, weight, BMI, weight loss • Operation type, chemotherapy regime

Timelines • August 2010: Ethics application • October 2010 – March 2011: Recruit • April – May 2011: Data analysis • June – September 2011: Write up • November 2011: Publish and Present

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