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Neuroscience Research Building & 310 South Newstead Parking Garage Project Orientation Revised May 13, 2020 Project Executive Committee Craig Schnuck Andy Newman Andrew Martin David Perlmutter Jennifer Lodge Rick Stanton Hank Webber


  1. Neuroscience Research Building & 310 South Newstead Parking Garage Project Orientation Revised – May 13, 2020

  2. Project Executive Committee Craig Schnuck Andy Newman Andrew Martin David Perlmutter Jennifer Lodge Rick Stanton Hank Webber Melissa Hopkins Jamie Kolker Steven Sobo

  3. Project Core Advisory Committee Jennifer Lodge Rick Stanton David Holtzman Charles Zorumski Paul Taghert Richard Wahl Michael Avidan Jeff Milbrandt Greg Zipfel

  4. Design & Construction Team Edwin Cordes (P&W) Trevor Calarco (CannonDesign) Andy Poirot (McCarthy)

  5. School of Medicine Strategic Research Growth Goals: FY 17 – FY 27 Achieve #2 rank in NIH Funding within 10 years + Washington University Add 160 funded mid-career scientists in aging & School of + personalized medicine, physician-scientists Medicine Research Goals + Recruit 10 BJC Investigators

  6. One Project Solves Three Urgent Needs Research space + A Plan for Vivarium space + the Future + Parking Which program(s) should we build for?

  7. World Class Neuroscience at the School of Medicine

  8. Why Neurosciences? • Aging, Personalized Medicine and Physician-Scientists • World class research, but no concen trated “home” – enable collaborations • Elevate the visibility of our excellence in the neurosciences • Attract companies to St. Louis/Cortex • Scattered vacated space to enable growth in other programs

  9. Planned Researchers and Departments – New Facility Baseline Program Inclusions +88 Neurology Researcher Neuroscience teams Neurosurgery Psychiatry Anesthesiology +1,280 Collaborators Genetics, Medicine, Ophthalmology, (net new) Otolaryngology, Pediatrics, Biomedical Engineering, Cars Developmental Biology Numerous Specialties / Cores +40,000 Cages & NHP

  10. Critical Success Factors • neuroscience ‘ins titute-lik e’ research groups (not departmental), enabling collaborations and high impact science • adaptable and flexible • Theme based – not department centric • Connect to rest of campus via the link

  11. Research Themes & Adjacencies

  12. Blocking and Stacking

  13. Blocking and Stacking

  14. Blocking and Stacking

  15. Planning Principles Collaboration / Thematic Research Efficiencies / Collocation & Shared Resources Adaptability & Flexibility / Neighborhoods & Specialty Lab Support

  16. Typical Floor Concept Elevators / T oilets Meeting / Collaboration / Open Stair Offices / Workstations 4 Research Neighborhoods 4 3 Specialty, Lab Support & 1 2 Linear Equipment Room (LER) VERTICAL Vertical Vivarium VIVARIUM

  17. Prototypical Research Neighborhood Central Building Utilities Power (120v/208v) Standby Power (3 W/SF) Data Compressed Air CO2 (where required) Lab Vacuum Water (Hot/Cold) RO water

  18. Prototypical Specialty & Lab Support Rooms

  19. Central Vivarium, First, Second, Third & Typical Laboratory Floorplans

  20. Basement floorplan (central vivarium)

  21. Level 1 floorplan

  22. Level 2 floorplan

  23. Level 3 floorplan

  24. Typical laboratory floorplan

  25. Level 10 floorplan

  26. Site Analysis / Context This building creates an edge for our campus, adds to our campus environment, and is respectful of our neighbors. The investments made are in support of the great science that will be happening inside and across the campus.

  27. Defines campus edge

  28. View Looking Northeast

  29. CORTEX ACCESS A T GRADE CENTRAL CAMPUS LINK TO CORTEX CAMPUS IMMEDIA TE A T LEVEL 3 SURROUNDINGS

  30. SLCH Garage Pathway Integration

  31. Site Section Looking West

  32. Schematic Design Current Scheme

  33. Neuroscience Research Building View from north View from northwest

  34. Neuroscience Research Building View from northwest

  35. Neuroscience Research Building View from northeast

  36. Neuroscience Research Building View from northeast View of link

  37. Project Schedule

  38. Milestones • Design Development Phase : April 17, 2020 • Super Structure (multiple packages) : May 22 & July 3, 2020 • Construction Documents (interiors) : December 4, 2020 • Substantial Completion : June 2023 • Occupancy Start Date : July 2023

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