Dr. Clmentine Bosch-Bouju PhD in Neuroscience Postdoc in - - PowerPoint PPT Presentation

dr cl mentine bosch bouju
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Dr. Clmentine Bosch-Bouju PhD in Neuroscience Postdoc in - - PowerPoint PPT Presentation

Dr. Clmentine Bosch-Bouju PhD in Neuroscience Postdoc in Neuroscience (2008-2011) (2011-2013) o Collge de France (Paris) o University of Otago (New Zealand) o Parkinsons disease o Parkinsons disease o Patch-clamp


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SLIDE 1
  • Dr. Clémentine Bosch-Bouju
  • PhD in Neuroscience

(2008-2011)

  • Collège de France (Paris)
  • Parkinson’s disease
  • Patch-clamp electrophysiology

recordings and 3D anatomy

  • Postdoc in Neuroscience

(2011-2013)

  • University of Otago (New Zealand)
  • Parkinson’s disease
  • Optogenetics and freely moving

electrophysiology

Deniau et al., 2010 Bosch et al., 2011; 2012 Nelson et al., 2013 Bosch-Bouju et al., 2013 Bosch-Bouju et al., in press

10 um

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SLIDE 2
  • Omega-3 play multiple beneficial

roles in the brain

  • There is a direct link between
  • mega-3 levels and depression in

patients

  • Mechanisms by which omega-3

could help to cure depression are poorly understood

Omega-3: Docosahexaenoic acid DHA (22:6n-3)

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SLIDE 3

Project funded by Agreenskills: omega-3 and depression

Social defeat protocol In vitro recording of neuronal plasticity

  • How depression affects endocannabinoid plasticity?
  • Can omega-3 supplementation restore cannabinoid plasticity?
  • Can omega-3 supplementation prevent depressive-like behaviours?