SLIDE 1
G A M M A S Y N C H R O N I Z A T I O N
P H A S E R E L A T I O N S H I P S
N E U R O N A L R H Y T H M S A F R A M E W O R K F O R U N D E - - PowerPoint PPT Presentation
N E U R O N A L R H Y T H M S A F R A M E W O R K F O R U N D E - - PowerPoint PPT Presentation
2 n d N E U RO M AT WO R K S H O P S TO C H A S T I C M O D E L I N G A N D S P I K E DATA A N A LY S I S N E U R O N A L R H Y T H M S A F R A M E W O R K F O R U N D E R S T A N D I N G I N T E R A C T I O N S I N T H E B R A I N
SLIDE 2
SLIDE 3
FRANCISCO VARELA
H O W D O E S T H E B R A I N
O R C H E S T R A T E T H E S Y M P H O N Y
O F E M O T I O N S , P E R C E P T I O N S ,
T H O U G H T S A N D A C T I O N S T H A T C O M E T O G E T H E R E F F O R T L E S S L Y F R O M N E U R A L P R O C E S S E S A C R O S S T H E B R A I N ?
— B Y S Y N C H R O N Y O V E R
M U L T I P L E F R E Q U E N C Y B A N D S .
NATURE REVIEWS, 2001
SLIDE 4
W H A T I S S P E C I A L I N
G A M M A S Y N C H R O N I Z A T I O N ?
ɣ
SLIDE 5
G R A Y e t a l . , N a t u r e , 1 9 8 9
B I N D I N G B Y S Y N C H R O N I Z A T I O N
T H E L O N G - B A R E X P E R I M E N T
SLIDE 6
B I N D I N G B Y S Y N C H R O N I Z A T I O N
C O N T R O V E R S I E S P A L A N C A e t a l . , N e u r o n 2 0 0 6 K R E I T E R a n d S I N G E R , J N S 1 9 9 6
SLIDE 7
C A S T E L O - B R A N C O . . N E U E N S C H W A N D E R … N a t u r e , 2 0 0 0
80
- 80
500 ms
Time (ms)
jeb012a02 2-2
1 1+2
0.2 0.0
Coincidences
Time L I M A … N E U E N S C H W A N D E R C e b C o r t e x , 2 0 1 0
B I N D I N G B Y S Y N C H R O N I Z A T I O N
C O N T R O V E R S I E S
80
- 80
500 ms
Time (ms)
jeb012a02 2-2
1 1+2
0.2 0.0
Coincidences
Time
SLIDE 8
SLIDE 9
S E L E C T I V E A T T E N T I O N
R O L E O F G A M M A O S C I L L A T I O N S
F R I E S E T A L . , S C I E N C E 2 0 0 1
In V4 cells activated by the attended stimulus show increased gamma-frequency (35 to 90 hertz) synchronization compared with neurons activated by distracters.
SLIDE 10
S E L E C T I V E A T T E N T I O N
R O L E O F G A M M A O S C I L L A T I O N S
F R I E S , N E U R O N 2 0 1 5
Selective coherence implies into selective communication.
SLIDE 11
m o d i f i e d f r o m W O M E L S D O R F , V I N C K , L I M A , . . N E U E N S C H W A N D E R , F R I E S P N A S , 2 0 1 2
S T I M U L U S E N C O D I N G W I T H G A M M A
P H A S E C O D I N G
In V1, orientation is encoded by phase relationships between spike and LFP signals.
SLIDE 12
B I N D I N G B Y S Y N C H R O N I Z A T I O N
C O N T R O V E R S I E S
T I C S , 2 0 1 5
SLIDE 13
D O G A M M A O S C I L L A T I O N S P L A Y A
R O L E I N V I S I O N ?
SLIDE 14
A R T I F I C I A L v s . N A T U R A L
S E E I N G F I X E D G A Z E
SLIDE 15
I T O , M A L D O N A D O , S I N G E R , G R Ü N C e r e b r a l C o r t e x . , 2 0 1 3
B E T A R E S P O N S E S
C A P U C H I N M O N K E Y
20 Hz
2 5 0 m s
S A C C A D E - O N S E T F I X A T I O N - O N S E T
SLIDE 16
B R U N E T … F R I E S C e r e b r a l C o r t e x . , 2 0 1 3
G A M M A R E S P O N S E S
M A C A Q U E M O N K E Y
SLIDE 17
B R U N E T … F R I E S C e r e b r a l C o r t e x . , 2 0 1 3
G A M M A R E S P O N S E S
M A C A Q U E M O N K E Y
SLIDE 18
B R U N E T … F R I E S C e r e b r a l C o r t e x . , 2 0 1 3
G A M M A R E S P O N S E S
M A C A Q U E M O N K E Y
SLIDE 19
G A M M A O F L F P
S T I M U L U S D I R E C T I O N O F M O V E M E N T
1-1
254
2-2
219
3-3
154
2°
Gamma modulation depends strongly on stimulus properties, such as orientation.
SLIDE 20
Center Periphery
R E C O R D I N G S F R O M C A P U C H I N V 1
SLIDE 21
C E N T E R v s . P E R I P H E R Y
G A M M A F R E Q U E N C Y D E P E N D S O N S P E E D
Gamma oscillation frequency is much high for central representation.
3.25 °/s 2.25 °/s 2.75 °/s 1.75 °/s 1.25 °/s 0.75 °/s
juj013b03 - 04
Speed (°/s)
Rate
3.2 0.7 2.0 160 70 sp/s 90 65 Hz
Freq
juj013a01
1°
3.5 °/s 2.0 °/s 2.5 °/s 3.0 °/s 1.5 °/s 1.0 °/s 0.5 °/s
juj011a04 juj011a03
17°
Speed (°/s)
Rate
3.5 0.5 2.0 180 120 sp/s 55 45 Hz
Freq
SLIDE 22
Does gamma oscillation frequency depends on visual map?
40 N= 129 N= 129 100 50 75 25 100 50 75 25
Power (z-score)
LFP 40 90 80 70 60 50 40 3° 10°
Peak freqency (Hz)
90 80 70 60 50 40 3° 10°
Eccentricity Frequency (Hz)
A B
nic077a03..04 1-1 3-3
2° 2°
L I M A , C H E N , S I N G E R , N E U E N S C H W A N D E R C E R E B R A L C O R T E X , 2 0 1 0
C E N T E R v s . P E R I P H E R Y
M A C A Q U E M O N K E Y
SLIDE 23
25 pixels
juj012a01
1°
25° 1° Stimulus size RF 20°
Direction 112.5° Spatial frequency 1.5 cycles/ ° Speed 2°/ s
FP
SLIDE 24
Gamma modulation increases dramatically with stimulus size. Frequency decreases.
250 ms
45 Hz Size (pixels)
100
30
Size MUA responses Power of LFP Rate
50 75 100 150 200 300 400 500
500 30 58 Hz 48 Hz 95 sp/s 325 0.50 0.07
Gamma Freq
juj012a05
1° 20°
G A M M A D E P E N D S O N S I Z E
SLIDE 25
T R I A L 1
F I X A T I O N E P O C H
SLIDE 26
F R E E - V I E W I N G E P O C H
T R I A L 1
SLIDE 27
T R I A L N
F I X A T I O N E P O C H
G R A T I N G S
SLIDE 28
T R I A L N
F R E E - V I E W I N G E P O C H
G R A T I N G S
SLIDE 29
G R E A T R E S P O N S E S T O G R A T I N G S
L F P G A M M A I N C A P U C H I N V 1
F I X A T I O N F R E E - V I E W I N G
SLIDE 30
F R O x C O R T I C A L G A M M A
O S C I L L A T I O N F R E Q U E N C Y D E C R E A S E
Direction 225° Speed 2°/ s
1°
FIXATION FREE-VIEWING
juj013b08
77 Hz
SLIDE 31
N A T U R A L S C E N E S
O P T I M A L D I R E C T I O N
1°
Direction 225° Speed 2°/ s
FIXATION FREE-VIEWING
juj013b08
SLIDE 32
I N S T I T U T O D O C É R E B R O - U F R N N A T A L
V I S L A B K A T I A - S I M O N E R O C H A ( M E S T R A D O ) L U A N A D A N T A S ( M E S T R A D O ) R A F A E L A F A U S T I N O ( D O U T O R A D O ) S E R G I O N E U E N S C H W A N D E R
S P E C I A L T H A N K S T O