MS Cow Udder SEPIA SEPIA Part of: Rundvee uierhygiene E - - PowerPoint PPT Presentation

MS Cow Udder SEPIA MS Cow Udder SEPIA

Part of: “Rundvee uierhygiene E presentation and Treatment … “

Application: Agriculture

MS Cow Udder SEPIA

MS Cow Udder SEPIA: Mastitis

Number(s) 1 in costs per animal

Mastitis: average € 83,= per cow per year € 285,= per mastitis cow

(source UGCN, The Netherlands)

Claw: average € 53,= per cow per year € 250,= per cripple cow

Cost overview mastitis

loss of milk € 121 medication € 50 Losses for not supplied milk € 43 Culling € 63

MS Cow Udder SEPIA: Mastitis

Cell counts

Mastitis

 Mastitis is an inflammation of the udder, typically caused by a microbiological infection.(95%)  Many types of microbes can cause infection and they can be transmitted from both

• environmental sources (for example,

contaminated water, soil, bedding) and from

• contagious sources (from other infected cows).

 Milk from cows infected with mastitis generally have higher total bacteria counts and somatic cell counts than milk from uninfected cows.

Somatic Cells  Somatic cells are cells from the cow (predominantly white blood cells, otherwise

known as leukocytes) that are normally present in milk.  During most mastitis infections, the number of somatic cells present in the udder increases to help the cow fight the infection.

MS Cow Udder SEPIA: Mastitis

Cell counts

Healthy cows will always have a certain cell count In case of mastitis the cell counts increases

In case of sufficient resistance the cell counts drops (again) In case of poor resistance the cell counts remains high (chronically infection) <100.000 cells/ml = healthy cow 100.000 – 250.000 = suspicious cow = attention cow >250.000 cells/ml = mastitis suspicious cow (at least 1 udder quarter infected) Note: >150.00 cells/ml = mastitis suspicious heifer (at least 1 udder quarter infected) EU norm = 400.000 (>> = penalty on milk price) Average NL (2011) = 187.000 Average B – VL (2010) = 234.000 Average B – W (2010) = 276.000 USA norm = 750.000 Average USA (2010) = 228.000

CMT test for cell counts

MS Cow Udder SEPIA: Mastitis

Mastitis

With mastitis we distinct beween clinical and subclinical mastitis. Both forms occur in the same way (a bacterium that enters the udder), but the way the disorder presents itself is different

Clinical mastitis: Characterized by abnormal milk, swelling, pain and sometimes fever. The cell count of the affected quarter is increased.

The seriousness of the phenomena depends on cow factors (among other lactation stage) and of the pathogenic properties of the bacterium. The treatment focuses primarily on improving the well- being of the cow (less pain, less sick), healing of the udder and recovery of milk production

Subclinical mastitis: Characterized by: No abnormalities to milk or udder visible The cow exhibits no signs of disease. Increased cell counts as well as increased conductivity

Here is the treatment primarily focused on healing of the damaged udder and this on reducing the infection pressure

MS Cow Udder SEPIA: Mastits

Microbiology

Bacteria Contamination via Related to cow (=contagious) Staphylococcus aureus Liners, skin, udder cloths, farmers hands Streptococcus agalactiae Cow tot cow = cross contamination Related to environment Colifoms (E-coli) Straw, manure, drinking water and (wet) polluted udder cloths Streptococcus uberis Straw (litter) and contamination by surroundings during milking, polluted cubicles, Klebsiella Polluted bedding/sawdust Related to environment – cow (= contagious) Streptococcus dysgalactia Damage of teats due to poor housing and/or poor operating milking machine Coagulase negative staphylococcus Collective name for several environment and cow related mastitis causing micro-

• rganisms

MS Cow Udder SEPIA: Mastitis

Multifactor Temperature and humidity Milking machine Feed Genetics Climate Housing Cubicle hygiene Calving

MS Cow Udder SEPIA: Mastitis

Guidelines

Mastitis – Improvement guide lines

 Proper housing  Optimal feed  Good hygiene before and during milking  Optimal operating milking machine (check 2x per annum)  Cows with high cell counts (>200.000) to be milked last  Regular microbiological tests to be executed on “attention” cows  Treat mastitis according description producer of medication  Register treatment and results  Remove chronically mastitis cases from the herd (>4 months “attention” cow)  Apply appropriate dry cow therapy  Follow the dry cow therapy for “attention” cows by microbiological tests  Consult with your veterinarian on a regular base And last but not least:

Use a proper teat dip or spray after milking

MS Cow Udder SEPIA MS Cow Udder SEPIA

2 major considerations

MS Cow Udder SEPIA: Udder care

Udder care: To be split in 2 major considerations The skin The streak canal

Skin Streak canal Stressed by milking and environment Potential entrance of bacteria

MS Cow Udder SEPIA: Udder care

The skin

A skin in a good condition offers protection against cold, heat, sunlight (UV light), pain, loss of moisture, loss of heat, water, dirt, pressure, abrasions, wounds, and infections The skin also offers support to the structure body (strength), heat regulation, dispose of waste, transpiration, sensation/detection, storage of fat, production vitamin D and much more

UDDER CARE = SKIN CARE & PROTECTION

MS Cow Udder SEPIA: Udder care

The skin and its residents Residential flora (Contagious?)

The permanent residents of the skin. Normally innocent, Never able to be removed for full 100%. Pathogenic species are f.e. Staphylococcus aureus, Streptococcus and others

Transient flora (Environment related?)

The micro-organisms are impermanent and often taken up from the

• environment. Species found are f.e. Clostridia, Salmonella, E-coli and
• more. They are normally more easy to be removed by water and soap than

the residential flora Layers of oil, hair and dead skin make detach more difficult

MS Cow Udder SEPIA: Udder care

The skin should be clean, but……

Results before washing A skin which is clean and in good condition will contribute to health and protection. Cleaning is nevertheless to be accompanied with a clear message. Good; otherwise better not!!. Results after washing Poor cleaning

MS Cow Udder SEPIA: Udder care

The streak/teat canal

Mastitis results when bacteria pass through the teat canal, overcome the defenses in milk and multiply. Organisms pass through the teat canal in several ways:

• 1. Between milking (Risk period of up to 1 hour after milking = teat canal
• pen. High risk 30-120 seconds after milking)

Organisms pass through the teat canal by multiplying inside the canal.

• 2. During machine milking,

Organisms may be propelled into through the teat canal into the teat cistern and udder

UDDER CARE = TEAT CANAL PROTECTION

MS Cow Udder SEPIA MS Cow Udder SEPIA

Pretreatment and Post treatment

MS Cow Udder SEPIA: Udder care

To be split in 2 major treatments

Pre-treatment (Before milking) MS Lavettes MS Udder paper MS Cow Udder MAGENTA Post-treatment (After milking) MS Cow Udder MAROON MS Cow Udder SEPIA MS Cow Udder SEPIA MS Cow Udder MAGENTA MS GSD/JODES

MS Cow Udder SEPIA MS Cow Udder SEPIA

Post treatment

MS Cow Udder SEPIA: Udder care

Post-treatment (treatment after milking)

The benefits to be gained from post-treatment:  Exclude penetration of the teat canal  protects  prevents cross contaminations  cares and (re)conditions  disinfects

MS Cow Udder SEPIA: Udder care

Post treatment: 2 major considerations The skin The streak canal

Skin Streak canal Stressed by milking and environment Potential entrance of bacteria

MS Cow Udder SEPIA: Udder care

A little chemistry

• PVP Iodine: Polyvinylpyrrolidon-Iodine, Iodine

CAS: 125655-41-8 2,5 -5,0% (2,5000 ppm)

• Glycerol: Glycerine

CAS 56-81-5

• Allantoin: Allanton, Allantan

CAS 97-59-6

• Propylene glycol: Methyl Ethyl Glycol (MEG)

CAS 57-55-6

• Nonionic and anionic surfactants, thickening agents

and auxiliary agents

MS Cow Udder SEPIA: Udder care

PVP Iodine

Polyvinylpyrrolidon-Iodine, Iodine

Povidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of infection in wounds and openings. Initially developed for human applications. Belongs to the group of oxidizing disinfectants and offer quick action at low

• temperatures. (oxidizing = low temperature, quick action, no resistance, low fouling tolerance)

Contains 1.100 ppm total Iodine (reservoir), corresponding with some 8 -10 ppm available Iodine, which is responsible for microbiocidal activity. Available Iodine being reacted away, will be complemented from the reservoir (auto- recovery) again

MS Cow Udder SEPIA: Udder care

PVP Iodine

Polyvinylpyrrolidon-Iodine, Iodine

PVP Iodine solution (10%) which is equivalent to 2500 ppm Iodine Nonylphenols en PVP Iodine

Nonylphenols are surfactants and belong to the alkyl phenols and alkyl phenol ethoxylates (APEO). Nonylphenols are banned from several EU markets because of environment (first and second degree biodegradability, skin irritation, allergic reactions and fertility issues)

Nonylphenols PVP

Acute oral toxicity (rat) 200-2000 mg/kg 9620-13000 mg/kg Skin irritation (rabbit) Corrosive Not Irritating Eye irritation (rabbit) >>> irritating Not Irritating

• Cumm. Toxicity oral (rat)

100 mg/kg 75-750 mg/kg Carcinogenetic Suspected Not carcinogenic Shelf life 1 year 3 years

MS Cow Udder SEPIA: Udder care

PVP Iodine

Polyvinylpyrrolidon-Iodine, Iodine

Cosmetic film forming emulsion

Excellent microbiocidal properties

CFU pe rml after treatment with MS Cow Udder SEPIA CFU per ml Before treatment with MS Cow Udder SEPIA Contact times 24 hrs 7 days 14 days 21 days 28 days 1,2x10E5 9,1x10E4 <10 <10 <10 <10 <10 2,42x10E5 1,06x10E5 <10 <10 <10 <10 <10 1,12x10E5 8,1x10E4 <10 <10 <10 <10 <10 1,07x10E5 8,8x10E4 <10 <10 <10 <10 <10 Conclusion Log 4 reduction within 24 hours

MS Cow Udder SEPIA: Udder care

Glycerin

Glycerol

Glycerol is used in medical and pharmaceutical and personal care preparations, mainly as a means of improving smoothness, providing lubrication and as a humectant. water movement

MS Cow Udder SEPIA: Udder care

Allantoin

Allanton, Allantan

Allantoin is moisturizing and keratolytic, meaning that it causes keratin in the skin to soften. This property helps skin to heal more quickly and to bind moisture more effectively, making products containing allantoin useful for dry skin and for healing wounds, burns, and scars. It is also effective against sunburn, chapped lips, cold sores, diaper rash, and similar skin irritations.

°C

MS Cow Udder SEPIA: Udder care

Propylene glycol

Methyl ethylene glycol (MEG)

Propylene glycol is regarded by the World Health Organization as non-toxic at low concentrations and is allowed to be used in food, cosmetics and

• medication. The E-number is 1520

 Applied in cosmetics because of its hygroscopic (moisterizing) properties  Acts as a solvent  Applied as a medication against Acetomie (Slepende melkziekte)

NMF

NMF NMF

NMF

NMF NMF

MS Cow Udder SEPIA: Udder care

Surfactants and thickening agents ensure a stable emulsion

MS Cow Udder SEPIA is a unique and above all very stable emulsion. Emulsion: A composition of 2 liquids which are normally not miscible. In MS Cow Udder SEPIA is extremely rich in emollients/skin conditioners (oil based) that it requires a stabilized emulsion.

Two immiscible liquids, not yet emulsified An emulsion of Phase II dispersed in Phase I The unstable emulsion progressively separates The surfactant positions itself on the interfaces between Phase II and Phase I, stabilizing the emulsion

Composition

Iodine 1.100 ppm as highly efficient disinfectant PVP Iodine for efficacy and high skin compatibility Rich in Glycerin, Allantoin and Propylene glycol as skin conditioners Thickening agents and surfactants for stabilized emulsion Thickening agents for sufficient product to the skin

MS Cow Udder SEPIA

MS Cow Udder SEPIA: Udder care

MS Cow Udder SEPIA: Udder care

USP’s

 Based on PVP Iodine; highly effective, quick action and mild for skin. Free

• f Nonylphenol Iodine

 Bactericidal efficacy already within seconds and ideal for protection of the

• pen teat canal immediately after milking

 Contains 1.100 ppm Iodine which offers a perfect balance between efficacy and skin conditioning in synergism with the rich volume emollients  Effective against Coli, Streptococcus, Staphylococcus, Pseudomonas, Streptococcus and Klebsiella, known to be mastitis pathogens  The perfect emulsion for optimum skin care, conditioning and

• reconditioning. Therefore suited for circumstances which stress the skin

(weather, sun, dry, abrasion and similar)

MS Cow Udder SEPIA: Udder care

USP’s

 MS Cow Udder SEPIA is derived from cosmetic knowledge, which means:

• It strengthens the hygroscopic properties (brings moisture to the skin)
• It strengthens the moisturizing properties (brings moisture in the skin)
• It strengthens the properties holding the moisture in the skin

 The cosmetic properties of MS Cow Udder SEPIA ensure the skin being supple, strong, repaired and protect it against stress from the environment (weather change, sun, dirt)  Applicable only in dip methods. Option is to use a “dipmizer”..  The product does not drip form the teats after application  Requires approx. 77 – 105 grams per 100 dipping operations

water movement

MS Cow Udder SEPIA: Udder care

USP’s

 pH of the product which is in line with the pH of the skin and also here contributing to optimum skin compatibility  Registered as biocide in NL. Ready for biocide regulation (EC/98/9 BPR)  Applicable for dairy, goats and sheep immediately after milking.  In principle applicable all-year-round, but specifically beneficial under circumstances of severe threats of skin condition  MS Cow Udder SEPIA is ready for use

MS Cow Udder SEPIA: Udder care

Applications

„SUPERIOR SKIN CARE“

MS Cow Udder SEPIA: Udder care

Directions for use

Dairy cattle

MS Cow Udder Sepia is ready for use A dip cup should be used. Spraying is not possible/recommended Prepare the dip cup before milking with the required volume MS Cow Udder Sepia It is possible to use a “Dipmizer” Apply the product immediately after milking and ensure full coverage of the teats Also ensure the cows not to lay down immediately after milking Clean the dip cup after use Do not return superfluous liquid to the original drum

Greasy piglets

MS Cow Udder Sepia is ready for use, but can also be diluted up to 1:4 with water Application should take place immediately after preparation Spray the affected piglets with the solution up to twice per day untill recovery Affected piglets should be kept apart from the group

MS Cow Udder SEPIA: Udder care

Product Information Leaflet

MS Cow Udder SEPIA: Udder care

Packaging 2509857: 20 kg

MS Cow Udder SEPIA: Udder care

Label

MS Cow Udder SEPIA MS Cow Udder SEPIA

Superior udder and skin care