Mapping Your Career With NIH Sherry Mills, MD, MPH Director, Office - - PowerPoint PPT Presentation

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Mapping Your Career With NIH

Sherry Mills, MD, MPH

Director, Office of Extramural Programs Office of Extramural Research National Institutes of Health

NIH Office of Extramural Research

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Overview

• Introduction to the NIH
• Becoming an NIH-supported Researcher:

– Loan Repayment Programs (LRPs) – Training and Fellowship Programs

• Your Questions

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National Institutes of Health

NIH ... Turning Discovery Into Health Our mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce the burdens of illness and disability.

 World’s largest source of funding for biomedical research  Support more than 300,000 research personnel at over 3,000 universities and research institutions  27 Institutes and Centers (ICs) with specific research agendas

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NIH and You

• New investigators entering the ranks of

independent, NIH-funded researchers is essential to the health of the biomedical workforce:

– Bring fresh ideas and technologies to existing biomedical research problems – Pioneer new areas of investigation – Continue to contribute to the pipeline

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Intramural Research: 10.0% R&D Contracts: 11.0% Research Project Grants: 53.0% Other Research: 6.0% All Other: 2.0% Research Mgmt & Support: 5.0% Research Training: 2.5% Research Centers: 10.0%

$794 M (2.5%) ‐ Training $652 M (2.0%) ‐ Career (Ks) $1.45 B (4.5%) ‐ Combined

FY 2012 Budget: $31.9 Billion

Includes Ks: 2%

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Tuition and Indebtedness: Young MDs

• Medical school median tuition & fees growth

(1984-2011)*:

– 604% increase for public medical schools – 567% increase for private medical schools

• Medical student median debt growth*:

– Public medical school students

• $22,000 in 1984
• $155,000 in 2011

– Private medical school students

• $27,000 in 1984
• $180,000 in 2011

*Source: AAMC “Medical School Tuition and Young Physician Indebtedness” report and Debt Fact Cards

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Loan Repayment Program National Research Service Awards Career Development Awards

NIH Funding Opportunities: Paths to Independent Research

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The NIH Research Application Process

• 1. Great Idea
• 2. Consult/collaborate

with others

• 3. Write an organized

proposal

• 4. Review

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My Application

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$$$

Center for Scientific Review

Assigns IRG in CSR

• r IC

Scientific Review Group

Evaluates Scientific Merit

Institute or Center (IC)

Evaluates Relevance

Advisory Council

Recommends Action

IC Director

Allocates Funds PI / Institution Submits application Conduct Research

The NIH Review Process

Revision / Resubmission

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Loan Repayment Program National Research Service Awards Career Development Awards

NIH Funding Opportunities: Paths to Independent Research

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NIH Loan Repayment Programs (LRPs): How They Work

LRPs are a vital component of our nation's efforts to attract health professionals to careers in research:

Increase the number of biomedical and behavioral research scientists NIH: Repays up to $35,000 per year of your qualified educational debt and pays 39% for federal taxes You: Commit to perform research for 2 years, with possible renewal

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Five Extramural LRPs

• Clinical Research
• Pediatric Research
• Health Disparities Research
• Contraception and Infertility

Research

• Clinical Research for

Individuals from Disadvantaged Backgrounds

Note: NIH employees in research positions are eligible for Intramural LRPs

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Eligibility

• Doctoral degree (M.D., Ph.D., or equivalent)
• EXCEPTION: Contraception and Infertility Research LRP
• Funding for research funded by a U.S. domestic

nonprofit, university, or government organization

**NIH grant or award support NOT required**

• Educational loan debt must be at least 20% of

applicant’s annual salary

• Must conduct qualifying research for at least 20

hours/week

• U.S. Citizen or permanent resident

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Qualifying Loans and Repayment

NIH will repay:

• Educational loans backed by the U.S. Government
• Educational loans from accredited U.S. academic institutions and

commercial lenders NIH will not repay:

• Non-education loans (e.g., home equity loans)
• Loans consolidated with another individual (e.g., spouse or child)
• PLUS loans to parents
• EXCEPTION: PLUS loans disbursed to graduate and

professional students on or after July 1, 2006, qualify for LRP repayment

• Loans converted to a service obligation
• Loans that are delinquent loans or in default

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Qualifying Loans and Repayment (cont.)

Individuals are not eligible for the NIH LRPs if they:

• Have a Federal judgment lien against their property

arising from a Federal debt

• Owe an obligation of health professional service to the

Federal Government, a state, or other entity, unless deferrals are granted for the length of their LRP service obligation

• NRSA T32, T90 and F32 awardees are eligible—NIH grants

automatic extensions of the NRSA service obligation.)

• Are a full-time Federal government employee or VA

Fellow

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Success Rates for LRPs

FY12 Applications Awards Success Rates

New 1,835 706 38.5% Renewal 1,265 848 67.0% Total 3,100 1,554 51.8%

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Awards by Doctoral Degree of Recipient (FY 2011)

LRP Physician Doctorate Professional Clinical Doctorate Academic Doctorate Physician Doctorate / Academic Doctorate Total Clinical Research 190 10 166 38 404 Pediatric Research 86 2 80 17 185 Health Disparities Research 27 94 1 122 Clinical Research for Individuals from Disadvantaged Backgrounds 8 1 7 1 17 Contraception and Infertility Research 8 1 7 1 17* Total 319 14 354 58 745

New Awards

*Does not include 2 Contraception and Infertility Awardees who did not have doctoral level degrees.

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Awardees by State (FY 2011)

California and Massachusetts had the most recipients, followed by New York and Pennsylvania.

AZ NM TX OK AR LA MS AL FL GA SC TN WA OR CA NV ID MT ND SD WY UT CO KS NE MO IA MN WI MI IN IL KY NC VA WV OH PA NY ME VT DE NJ CT HI NH RI MD PR DC MA

Number of Participants States*

AK,ID,ME,NV,WV,WY 1 -25 AL,AZ,AR,DE,DC,HI,IN,IA,KS KY,LA,MS,MT,NE,NH,NJ,NM,ND OK,OR,PR,SC,SD,UT,VT 26-50 CO,CT,FL,GA,MI,MN,MO,OH RI,TN,VA,WI 51-100 IL,MD,NC,TX,WA 101-150 NY,PA 151-200 CA,MA

AK

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Online Information and Application Application Deadline November 15 http://www.lrp.nih.gov

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Connect with Us

Resources: http://www.lrp.nih.gov/resources

• LRP Ambassador Network: connect with current and past recipients
• Webinars
• Tools and training for the applying

Social Media: Follow us on Facebook: http://www.facebook.com/nihlrp Follow us on Twitter: @ NIH LRP Subscribe to our listserv NIH_LRP list (https://list.nih.gov/cgi- bin/wa.exe?SUBED1=nih_lrp&A=1)

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Loan Repayment Program National Research Service Awards Career Development Awards

NIH Funding Opportunities: Paths to Independent Research

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Research Career Track (e.g. Ph.D.)

Graduate student Independent PI Ph.D. Faculty Position

T32 F31 F32

• r

T32 K22 R01 R37 K02 F33 R21 R03

Diversity Supplements

K99/ R00 Ps Us

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Clinical Career Track (e.g. MD)

Medical Student Independent PI M.D. Faculty Position

T35 T32

• r

F32 R01 R37 K08

• r

K23 K22

Clinical Training

K02 K24 F33 R21 K99/ R00 Diversity Supplements F30 NIH Intramural Summer Internships

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Ruth L. Kirschstein National Research Service Awards

Overview:

“help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical, behavioral, and clinical research needs.”

NRSA Opportunities:

• Training grants (Ts): Multi-slot

awards that are used to support research training activities for several individuals.

• Fellowships (Fs): Awards for

graduate students working on a doctoral degree and researchers who have just earned their doctorates (postdocs).

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Fellowships

Overview:

• Awarded to Predoctoral or

Postdoctoral fellows who are working with mentors.

• Training can be at domestic or foreign

institutions.

• Opportunities in basic and/or clinical

research.

• Open to any scientific area within the

NIH scientific mission.

• PhDs and MD/PhDs receive most of

the awards. F-Kiosk:

http://grants.nih.gov/training/F_files_nrsa.htm

Core Review Criteria: 1. Fellowship Applicant – Academic record and training, publications, etc. 2. Sponsors, Collaborators, and Consultants 3. Research Training Plan 4. Training Potential 5. Institutional Environment & Commitment to Training Additional Review Consideration: 1. Training in the Responsible Conduct of Research

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F30 and F31 Predoctoral Fellowships

Overview:

• Support Predoctoral Fellows during

graduate (possibly medical) training.

• F30 (MD/PhD) may support up to 6

years of training.

• F31 is limited to 5 years total.
• Promising doctoral candidates who

will be performing dissertation research.

• Some Institutes and Centers only

support Diversity F31s.

• Fellows may not change the scope,

move fellowship, or change mentor without prior NIH approval!

Program Features:

• Stipend:

 FY 2012: $22,032

• Tuition/Fees:

 60% of requested tuition, capped at $16,000 ($21,000 for MD/PhD programs)

• Institutional Allowance:

 $4,200  Includes health insurance

• Travel Allowance:

 Part of Institutional Allowance

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Success Rates for Fellowships

FY 2011 Success Rate F30 34% F31 34% F32 26%

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Loan Repayment Program National Research Service Awards Career Development Awards

NIH Funding Opportunities: Paths to Independent Research

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Career Development Awards

Overview:

• Individual and Institutional Awards.
• Opportunities for basic and clinical

investigators.

• Mix of mentored and independent

mechanisms.

• Some designed as awards for faculty

investigators.

• Newer programs (K22 and K99/R00)

are transition awards for MDs and PhDs. K-Kiosk: http://grants.nih.gov/training/careerdevelo pmentawards.htm Core Review Criteria:

• 1. Candidate
• 2. Career Development Plan/Career

Goals & Objectives (or Plan to Provide Mentoring*)

• 3. Research Plan
• 4. Mentor(s), Consultants(s) and

Collaborator(s)

• 5. Environment and Institutional

Commitment to the Candidate Additional Review Consideration: 1. Training in the Responsible Conduct of Research

* For Independent K awards

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K01 Mentored Research Scientist Development Award

Overview:

• Supports an intensive, supervised

career development experience in the biomedical, behavioral, or clinical sciences leading to research independence.

• Some ICs use the K01 for individuals

who propose to train in a new field or those who have had a hiatus in their research career.

• Some ICs utilize the K01 award to

increase research workforce diversity.

• Primarily for PhDs or equivalent

research doctoral degrees.

Program Features:

• Duration: 3 to 5 years
• Salary Support: Up to legislative

cap (varies by Institute/Center) – Most common salary cap is $75,000

• Research Support: Up to

$50,000/year (varies by Institute/Center)

 Institute and Center contacts and policies: See Funding Opportunity Announcement

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K08 Mentored Clinical Scientist Development Award K23 Mentored Patient-Oriented Research Career

Development Award

Overview:

• K08: Supports individuals with a

clinical doctoral degree for a period of intensive, supervised research career development experience in the fields

• f biomedical and behavioral

research, including translational research.

• K23: Supports career development of

investigators who have made a commitment to patient-oriented research.

• Majority of awardees are MDs and

MD/PhDs.

Program Features:

• Duration: 3 to 5 years
• Salary Support: Up to legislative

cap (varies by Institute/Center) – Most common salary cap is $75,000

• Research Support: up to

$50,000/year (varies by Institute/Center)

 Institute and Center contacts and policies: See Funding Opportunity Announcement

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K25 Mentored Quantitative Research Development Award

Overview:

• For investigators whose quantitative

science and engineering research has thus far not been focused primarily on questions of health and disease.

• Supports a period of supervised study

and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.

Benefits

• Duration: 3 to 5 years
• Salary Support: Up to legislative

cap (varies by Institute/Center)

• Research Support: up to

$50,000/year (varies by Institute/Center)

 Institute and Center contacts and policies: See Funding Opportunity Announcement

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K22 Research Scholar Development Award

Overview:

• Facilitates the transition of

investigators from the mentored stage

• f career development to the

independent stage.

• Typically, transition award for

Postdocs moving to assistant professor positions.

Two Phases:

• Phase 1: May or may not be affiliated

with an institution. Some IC’s require NIH Intramural experience

• Phase 2: Assistant professor with own

lab and little to no teaching and administrative responsibilities.

Program Features:

• Duration: 2 years mentored

(Intramural), followed by 3 years independent

• Salary Support: Up to legislative

cap (varies by Institute/Center)

– None during Intramural phase

• Research Support: up to

$50,000/year (varies by Institute/Center)

– None during Intramural phase  Institute and Center contacts and policies: See Funding Opportunity Announcement

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K99/R00 Pathway to Independence Award

Overview:

• To facilitate a timely transition from a

mentored postdoctoral research position to a stable independent research position with independent NIH or other independent research support at an earlier stage than is currently the norm.

• Transition award for postdocs moving

to assistant professor positions (tenure track or equivalent)

• Supported by almost all ICs with

variations

• No citizenship/green card requirement

Program Features:

• K99 Phase

– Mentored Phase: Up to 2 years – Research Support: Up to $90,000/year (most Institutes & Centers provide more funds)

• R00 Phase

– Independent Phase: Up to 3 years; 75% effort – Research Support: $249,000/year

 Institute and Center contacts and policies: See Funding Opportunity Announcement

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Success Rates for Career Awards

FY 2011 Success Rate K01 33% K08 41% K23 34% K99 22%

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NIH New Investigator Policies

• New investigators are considered essential to the vitality of health‐

related research, thus several NIH initiatives to nurture promising scientists.

• New Investigators receive special attention at Council as high

program priority.

• No imposed reductions in duration and amount of awards (beyond

the recommendations of the initial review group) for New Investigators.

• Fund applications to achieve a designated success rate rather than

setting a specific payline for New Investigators applying for R01s.

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Advice for Mapping Your Career With NIH

• Review Institute/Center (IC) priorities and goals. Each IC has a

research training and career development program.

• Learn the NIH application and review process
• Identify the grant programs offered by each IC
• Make early contact with program officers
• Find innovative, well-respected mentors and collaborators
• Study successful grant applications- talk to your mentor
• Propose your best and most creative ideas
• Apply (and then persevere): “It's not that I'm so smart, it's just

that I stay with problems longer.” – Albert Einstein

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Resources

• NIH Office of Extramural Research: http://grants.nih.gov
• NIH Research Training and Career Development:

http://grants.nih.gov/training, including:

– Career Award Wizard – NRSAs – Career Developments Awards

• NIH Loan Repayment Programs:

http://www.lrp.nih.gov/index.aspx

• NIH New and Early Stage Investigator Policies:

http://grants.nih.gov/grants/new_investigators/index.htm

Follow us on Twitter: @ NIHforFunding