15.07.2019 Mannheim Medical Technology Cluster Dr. Elmar Bourdon Head of Healthcare Industry, City of Mannheim Head of Project MMT-Campus PREMIUM HIGHWAY ACCESS PREMIUM HIGHSPEED-TRAIN ACCESS 0:31h ICE to FRA AIRPORT 2:58h ICE to MUNICH 3:09h ICE to PARIS 2 1
15.07.2019 MEDTECH ENVIRONMENT Medical Technology in Mannheim Medical Technology Cluster 100+ Enterprises Mannheim + Approx. 10.000 1 hour car drive Workforce 3 SELECTED MEDTECH COMPANIES IN MANNHEIM AND WITHIN 1 HOUR CAR DRIVE AROUND 4 2
15.07.2019 THEREOF GLOBAL CORPORATIONS Abbott Diagnostics Leica Micro/Biosystems Abbvie Pharma LeMaitre Bausch & Lomb Medical MAQUET BD (Becton Dickinson) Merck Bruker Merck Serono C.R. Bard Nestlé Healthcare Datascope Pfizer Pharma Dentsply Sirona Roche Diagnostics Fresenius Medical Care Sanofi Aventis Heraeus Medical Siemens Healthcare Hitachi High-Technologies Terumo Johnson & Johnson DePuy Johnson & Johnson LifeScan 5 CLINICAL OPPORTUNIT Y MANNHEIM provides you quick access to key opinion leaders in high-volume centers in MANNHEIM City and 10 miles around : � Mannheim University Hospital (1.400 beds) � Mannheim Theresien-Hospital & St. Hedwig (660 beds) � Mannheim / Speyer Diakonie Hospital (540 & 440 beds) � Ludwigshafen Hospital (940 beds) � BG Ludwigshafen Trauma Surgery Center (450 beds) � Heidelberg University Hospital (1.700 beds) � For further information visit: www.medtech-mannheim.de/en/research-clinics 6 3
15.07.2019 RESEARCH OPPORTUNITY YOUR FAST TRACK TO CLINICAL RESEARCH ORGANISATIONS Deep therapeutic knowledge and understanding of clinical development drives more efficient pathways to commercialization. Whether you are conducting a clinical study or are managing a product life-cycle, MANNHEIM includes CROs dedicated to support you. The following shortlist presents just a sample of CROs in MANNHEIM: � PharmaLex � AMS Advanced Medical Services � PRA International � CONET Clinical Operations Network � CRS Clinical Research Services Andernach � QUINTILES Innovex � Dr. Knoell Consult � Scope International � Institute or Heart Attack Research � SynapCon Limited � Invisio Clinical Studies Consulting & Services � Study Center of the German Society of � IST Clinical Research Surgery � KKS Coordination Center for Clinical Studies 7 RESEARCH OPPORTUNITY YOUR FAST TRACK TO PHYSICIAN TRAINING Physician training is key to launching medical devices, and to drive adoption and diffusion of new medical technologies. The MANNHEIM medical technology cluster provides you quick access to simulator centers dedicated to physician training in surgical and transcatheter therapies: � CatHi Simulator Training Center � CardioSkills Simulator Training Center � VRmagic Eyesi Simulator Training Center 8 4
15.07.2019 RESEARCH OPPORTUNITY YOUR FAST TRACK TO A POWERFUL R&D ECOSYSTEM MANNHEIM provides access to a powerful ecosystem of collabortive clinical research an product R&D: � Central Institute of Mental Health � European Laboratory for Molecular Biology (EMBL) � Fraunhofer Group for Automation in Medical Engineering and Bioengineering � Mannheim University of Applied Sciences � Freudenberg New Technologies GmbH � Max-Planck-Institute for Medical Research � German Cancer Research Center (DKFZ) � National Tumor Center (NCT) � Heidelberg University Medical Center � Roche Diagnostics Research Center Mannheim � Intitute of Medical Technology Mannheim � Mannheim University Medical Center 9 SKILLED LABOUR OPPORTUNITY & ACCESS TO EXPERTS YOUR FAST TRACK TO DEDICATED MEDTECH EXPERTS MANNHEIM provides direct access to a dedicated group of experts that offer specific consulting services to adress the key challenges of medical device start-ups and SMEs in four critical areas. Start-ups and SMEs based in Mannheim can apply for subsidies for using those consulting services. 10 5
15.07.2019 SKILLED LABOUR OPPORTUNITY & ACCESS TO EXPERTS YOUR FAST TRACK TO TALENTS & PROFESSIONALS MANNHEIM provides quick access to leading academic institutions dedicated to providing a ready pool of graduates for medical device R&D, operations, supply chain, QA, regulatory, marketing, sales and distribution: � University of Applied Science (Medical Engineering) � Medical Faculity Mannheim of Heidelberg University (Medicine) � DHBW Cooperative State University (Electrical/Medical Engneering) � Graduate School RN (Life Science & Healthcare Management) � Mannheim University (Business) � University of Applied Management Studies (Business) � Vocational colleges for nurses and nurse-technicians 11 SERVICES FOR YOU IN MANNHEIM READY-TO-GO SALES OFFICE IN MANNHEIM The initial set-up of your German/EU direct sales organization The Ready-to-go Sales Office may take care of the rest, i.e.: may present a significant challenge to both, your P&L as well as your risk profile and management resources. � regulatory/legal Status of »Inverkehrbringer von Medizinprodukten durch Herstellung oder Einfuhr« acc. to german medical device law MPG When setting up your German/EU direct sales affiliate in � customer service / order taking Mannheim, you will be able to address those challenges using � local warehouse the Ready-to-go Sales Office: Just hire your own local sales � order processing organization, and focus 100% on customers & taking market � consignment stock mngt. share. � shelf life mngt. � local recall mngt. � invoicing � accounts recievables mngt. � accounting, forecasting, reporting 12 6
15.07.2019 START-UP & COMPETENCE CENTER MEDICAL TECHNOLOGY � Site: University Medical Center Mannheim � 1.800m² floor space � 7 offices (16m²) � 16 iCubes (25m²) � Lounge, Meeting Room, Event Space and Kitchen � Fraunhofer Project Group for Automation in Medicine and Biotechnology with experimental Intervention Suite / Hybrid OR � BMBF Research Campus M²OLIE 13 Mannheim Medical Technology Campus – MMT Campus Short distance to companies, clinicians and research . Developing products faster and more effectively. Ready 09/2020 Ready now • Building Phase I bis IV • 20.000m² Office-, Workshop-, Laboratoy- and Cleanroom Space in Phase I • Redundant Fibre Glass Data Connection • Business-Restaurant / Conference Center • Streets ready in May 2018 • Buidling construction starts March 2018 • Key-ready move-in June 2019 Your cup of hot coffee will not even stand a chance to cool down on the way. 14 7
15.07.2019 FINANCIAL PERFORMANCE AND COMPLAINCE IN MANNHEIM Financial performance and compliance according to international standards present key metrics for managing your business. Four worldwide leaders in business & strategy consulting run offices in Mannheim City, and provide business consulting, finance, taxation, accounting, and payroll services to you on site: � Ernst & Young � Deloitte � KPMG � PriceWaterhouseCoopers 15 Mannheim Medical Technology Cluster Dr. Elmar Bourdon Phone +49 621 293 2155 Email: elmar.bourdon@mannheim.de Yvonne Soyke Phone +49 621 293 3367 Email: yvonne.soyke@mannheim.de 16 8
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