<log 10 s> 0 1 2 2 log 10 s max 1 0 1 2 L L e B B - - PowerPoint PPT Presentation

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log 10 s

<log 10 s> 0 1 2 2 log 10 s max 1 0 1 2 L L e B B - - PowerPoint PPT Presentation

Feb 10, 2023 353 likes •432 views

Antigen processing and presentation all genes sink node genes

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SLIDE 1

Antigen processing and presentation

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all genes

maximum = 3

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sink node genes

maximum = 2 −2 −1 1 2

<log10 s>

−2 −1 1 2

log10 smax

m B L i n t e r m e d i a t e n

n

− m B L

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SLIDE 2

CD74 CD74 HLA−DMA NFYA RFX5... CREB1 CIITA CTSB LGMN CD74 CD74 CTSB LGMN IFI30 K10784... K10784... CD4 KIR2DS2 CD8A TAPBP CALR PDIA3 B2M B2M B2M HLA−A 100509457... 100509457... 100509457... HLA−A HLA−A HLA−A TAP1 HLA−A CANX HSPA5 HSP90AA1 HSPA1A PSME3 TNF IFNG Proteasome T cell receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway

Antigen processing and presentation (genes with data)

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SLIDE 3

CD74 CD74 HLA−DMA NFYA RFX5... CREB1 CIITA CTSB LGMN CD74 CD74 CTSB LGMN IFI30 K10784... K10784... CD4 KIR2DS2 CD8A TAPBP CALR PDIA3 B2M B2M B2M HLA−A 100509457... 100509457... 100509457... HLA−A HLA−A HLA−A TAP1 HLA−A CANX HSPA5 HSP90AA1 HSPA1A PSME3 TNF IFNG Proteasome T cell receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway

Antigen processing and presentation (sink nodes)

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SLIDE 4

CD74 CD74 HLA−DMA NFYA RFX5... CREB1 CIITA CTSB LGMN CD74 CD74 CTSB LGMN IFI30 K10784... K10784... CD4 KIR2DS2 CD8A TAPBP CALR PDIA3 B2M B2M B2M HLA−A 100509457... 100509457... 100509457... HLA−A HLA−A HLA−A TAP1 HLA−A CANX HSPA5 HSP90AA1 HSPA1A PSME3 TNF IFNG Proteasome T cell receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway

Antigen processing and presentation mBL

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SLIDE 5

CD74 CD74 HLA−DMA NFYA RFX5... CREB1 CIITA CTSB LGMN CD74 CD74 CTSB LGMN IFI30 K10784... K10784... CD4 KIR2DS2 CD8A TAPBP CALR PDIA3 B2M B2M B2M HLA−A 100509457... 100509457... 100509457... HLA−A HLA−A HLA−A TAP1 HLA−A CANX HSPA5 HSP90AA1 HSPA1A PSME3 TNF IFNG Proteasome T cell receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway

Antigen processing and presentation intermediate

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SLIDE 6

CD74 CD74 HLA−DMA NFYA RFX5... CREB1 CIITA CTSB LGMN CD74 CD74 CTSB LGMN IFI30 K10784... K10784... CD4 KIR2DS2 CD8A TAPBP CALR PDIA3 B2M B2M B2M HLA−A 100509457... 100509457... 100509457... HLA−A HLA−A HLA−A TAP1 HLA−A CANX HSPA5 HSP90AA1 HSPA1A PSME3 TNF IFNG Proteasome T cell receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway

Antigen processing and presentation non−mBL