Laparoscopic Liver Resection Ten year experience in one center Tran - - PowerPoint PPT Presentation

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Laparoscopic Liver Resection Ten year experience in one center Tran - - PowerPoint PPT Presentation

Laparoscopic Liver Resection Ten year experience in one center Tran Cong Duy Long MD. Nguyen Hoang Bac MD. University Medical Center Ho Chi Minh City Vietnam Laparoscopic Liver Resection in UMC Ho Chi Minh City Vietnam The development


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Tran Cong Duy Long MD. Nguyen Hoang Bac MD.

Laparoscopic Liver Resection

Ten year experience in one center

University Medical Center Ho Chi Minh City Vietnam

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  • The development progress
  • Surgical techniques
  • Short and long-term results

Laparoscopic Liver Resection in UMC Ho Chi Minh City Vietnam

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Laparoscopic Liver Resection Surgical techniques

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Technical demanding in liver resection

Inflow control

Total inflow control Selective inflow control

Outflow control

Low CVP (Anesthesiologist assistance) IVC Clamping

Parenchymal transection

Surgical instrument, energy devices,,… Surgeon experience, skill...

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Total inflow control - Pringle maneuver

Decrease blood supply Minimize bleeding Total liver ischemia Non-anatomic liver resection

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No dissection in liver hilus Decrease post-op ascites Selective inflow control Minimize remnant ischemia

Hemi inflow control

Simple and effective for right side segmentectomy in cirrhotic liver

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Laparoscopic Left lateral sectionectomy

University Medical Center - Ho Chi Minh - Vietnam

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Innovation in the technique

Left lateral Sectionectomy

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Technichal innovation

Left lateral Sectionectomy

University Medical Center - Ho Chi Minh - Vietnam

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Innovation in the technique

Segmentectomy 3

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Laparoscopic Left medial sectionectomy

University Medical Center - Ho Chi Minh - Vietnam

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Technichal innovation

Left Medial Sectionectomy

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Laparoscopic Major Hepatectomy...? Liver hilar dissection

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Glissonean structures

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Technichal innovation

Liver Hilar Dissection

How’s … in laparoscopic techniques ?

Extrahepatic Approach Intra Glissonean Dissection Individual ligation Intrahepatic Approach Extra Glissonean Dissection

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Isolating Portal Vein, Artery and Bile duct Time consuming Avoiding complication (Abnormal variation) Increasing ascites Anatomical Sectionectomy ? Segmentectomy ?

Suitable for Right or Left Anatomic Hepatectomy

Intra Glissonean Dissection Individual ligation

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Extra Glissonean Approach Right hepatectomy

University Medical Center - Ho Chi Minh - Vietnam

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University Medical Center - Ho Chi Minh - Vietnam

Laparoscopic Left Liver Resection

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Parenchymal-sparing liver resection Laparoscopic Anatomic Sectionectomy

University Medical Center - Ho Chi Minh - Vietnam

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Technical innovation Right Anterior Sectionectomy

University Medical Center - Ho Chi Minh - Vietnam

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Laparoscopic right posterior sectionectomy

Right posterior Glissonean pedicle clamping Anatomical transection plane

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Laparoscopic liver resection Extra Glissonean Dissection

Minimizing liver hilus dissection

Decreasing ascites Avoiding complication (Anatomic variation)

Selecting inflow control

(Sectors Gilssonean pedicles)

Identifying sector limitation Performing Anatomic Resection

Minimize bloodloss Better oncologic results

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Extra-Glissonean Approach Feasible and effective in laparoscopic liver resection technique

University Medical Center in Ho Chi Minh - Vietnam

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How to do Liver parenchymal transsection

  • Selective Glissonean pedicle controled
  • Low CVP controled
  • Anatomic transection

Intersegmental plane

  • Caudate approach

Criteria steps of technique

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Laparoscopic liver resection

Caudate approach

(Source: Wakabayashi et al)

“…to the liver hilum and IVC”

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Liver parenchymal transsection

  • Instruments

Harmonic scalpel CUSA Bipolar Hem o lok Stapler

How to do liver parenchymal transection…

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Recent cases... with a tumor located in caudate lobe

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Recent cases... Lap caudate lobectomy

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Laparoscopic Liver Resection Short and long term results

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Our result of Lap liver resection

04 cases Diagnostic Lap 11 cases Conversion 260 cases Lap Liver Resection 275 patients Indicated for Lap Liver Resection From Jan, 2007 to Jun, 2014

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Patients features

Tumor size Mean tumor size: 3,85 cm. (1 cm, 12 cm) Stage of desease, BCLC classification Very early (BCLC 0): 13,8% Early (BCLC A): 65,0% Intermediate (BCLC B): 21,2%

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Type of resection

Type of resection Quantity Percent One segment Segment II 11 4.2 Segment III 11 4.2 Segment IV 14 5.4 Segment V 22 8.5 Segment VI 51 19.6 Segment VII 7 2.7 Segment VIII 2 0.8 Two segments Posterior sector 9 3.5 Anterior sector 7 2.7 Segment V & VI 20 7.7 Left lateral sector 82 31.5 Three segments Left liver 13 3.0 Central hepatectomy 2 0.8 Four segments Right liver 9 3.5 Total 260 100

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Safety of laparoscopic liver resection

Complications Number Percentage None 247 95,0 Bile leakage 2 0,77 Ascites 4 1,54 Hemorrhage 2 0,77 Pneumonia 2 0,77 Pleural effusion 3 1,15 Total 260 100

Overall complications: 13 patients (5 %) No mortality

Clavien-Dindo Classification: I (8 patients), II (2 patients) IIIA: 1 patient with pleural effusion  Thoracentesis IIIB: 2 post op hemorrhage  Reoperation

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Disease-free survival

Months Disease-free rate

Time 1 year 2 year 3 year 4 year 5 year Percent 79,3% 64,5% 56,0% 51,2% 46,8%

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Overall survival

Months Disease-free rate

Time 1 year 2 year 3 year 4 year 5 year Percent 96,4% 84% 78,7% 77,3% 77,3%

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Summary

With experience in performing Laparoscopic liver resection

  • Feasible and safe
  • Technique were standardized

Extra Glissonean pedicle dissection Caudate approach

  • Extended Indication: major, central liver resection
  • Oncologic results: comparable with open surgery
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Why we do ... lap surgery...?

Liver Resection

Why we do ... open...?

Maybe...in near future...

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Why…Laparoscopic Liver Resection?

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Liver Special anatomic position Liver resection Highly invasive surgery

Liver resection

Minimizing the invasion of treatment most expected innovation in surgery

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Lap liver resection

First performed by Gagner (1992) Through a long journey of developing… We have got great achievements – Initial dificulties were overcome – Surgical techniques were gradually standardized – Indications were extended

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Current status of Laparoscopic Liver Resection

  • Challenging tumor location

– Posterior, superior segments

  • Major and difficult hepatectomy

− Right or left hepatectomy − Central hepatectomy − Caudate lobectomy

  • Anatomical resection

– Better oncologic results

  • Lap Donor Hepatectomy
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  • During the dissection of the liver

parenchyma, there are no small branches

  • of the Glissonean pedicle, but only

branches of the hepatic vein across the

  • cut surface
  • intersegmental plane
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The most favorable indications for the laparoscopic resection Solitary lesions Smaller than 5 cm Located in peripheral liver segments 2 to 6. Left lateral sectionectomy, anterior segmentectomies

  • r

wedge resections were the most widely applied procedures. Major liver resections were shown to be feasible but remain difficult procedures

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Laparoscopic right liver resection

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Extra Glissonean Dissection Right hepatectomy

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Laparoscopic Right Liver Resection