Laboratory- derived measures of critical intensity: what's new? - - PowerPoint PPT Presentation

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Laboratory- derived measures of critical intensity: what's new? - - PowerPoint PPT Presentation

Jan 14, 2023 39 likes •300 views

Laboratory- derived measures of critical intensity: what's new? Silvia Pogliaghi, MD, PhD DIPARTIMENTO DI NEUROSCIENZE, BIOMEDICINA E MOVIMENTO Exercise-intensity domains: Exercise duration, VO2 profile, change in intracellular composition

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Laboratory- derived measures

  • f critical intensity: what's new?

Silvia Pogliaghi, MD, PhD DIPARTIMENTO DI NEUROSCIENZE, BIOMEDICINA E MOVIMENTO

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Jones AM and Poole DC, 2005

Exercise-intensity domains:

Exercise duration, VO2 profile, change in intracellular composition

Heavy-Severe boundary

Increasing Metabolic instability

Steady-state non tenable Inefficiency, intolerance Delayed homeostasis Valid identification is essential for individualised quantification

  • f exercise «dose»
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Why measure heavy- severe boundary?

SUBMAXIMAL INDEX OF AEROBIC FITNESS SENSITIVE TO AEROBIC TRAINING INDICATOR OF “INTERNAL LOAD” TARGET INTENSITY FOR EXERCISE TRAINING DETERMINANT OF SPORT PERFORMANCE

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How to measure?

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VT

IAT

Dmax

CP

OBLA

LT2

RCP

AT HRDP MLSS VT2

VAM

How to measure?

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COST (time, equipment, expertiese) EFFORT (children, patients, motivation) RISK (older adults, patients) Objectivity (RCP) Correspondance between measures

Alternatives? What’s new?

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Can we determine critical intensity from deoxyHb profile? Correspondence with gold standard

# Age (yrs) Weight (kg) Stature (m) BMI VO2max (mL·kg-1·min-1) Mean ± SD Range 32 48±17 23-74 76 ± 8 62-98 1.75±0.09 1.56-1.90 25±3 20-31 39.4 ± 11.4 21.8-59.8

Bellotti C, MSSE 2013

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MLSS deoxyHbBP VO2 (L·min-1) 2.25 ± 0.54 2.23 ± 0.59

Bellotti C, MSSE 2013

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deoxyHbBP and RCP

Murias JM, RPNB 2013 Fontana FY, JSMC 2015 N=20 N=118

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Can maximal effort be spared?

EFFORT RISK COST

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6 8 10 12 14 16 2 4 6 8 10 12 VOBLA (Km/h) [LA] (mmol/l)

Sirtori M.D. e coll. Med.Sport 46: 281-286, 1993

13,5 Km/h, 6 min

y = (-0.575 * x) + 15.73 r2 = 0.86

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14 ♂ 31 ± 7 yrs

(range 23-44)

49 ± 7 ml*Kg-1*min-1

(range 44-65)

Fontana FY, JSS 2016

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Fontana FY, JSS 2016

Vs validated intensity

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SUBJECTS: 40 healthy ♂: 42±18 years (range 22-78), 48±8 ml Kg-1 min-1 (range 25-68)

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50 100 150 200 250 300 350 difference between measures (watt)

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100 200 50 100 150 200 250 300 350 estimated critical power (watt) 50 100 150 200 250 300 350 r = 0.89 p < 0.001 b0 = 17.97; b1 = 0.91 SEE = 19.9 W 40 50 60 70 80 90 100

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100 200 Bias = 1.5 Precision = 20.3 z = 0.95; p= 0.33 b1 = 0.13 ; b0 = -7.63 p = 0.41

A B C

average between measures (watt) difference between measures (watt) % peak power output 20 30 40 50 60 70 80

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  • 100

100 200

D

difference between measures (watt) age (yeras) b1 = 0.00 ; b0 = 0.01 p = 0.99 r = 0.91 p < 0.001 b0 = 0.13; b1 = 0.99 SEE = 18 W Bias = 0.02 Precision = 18.3 z = 0.01; p= 0.99 b1 = 0.27 ; b0 = -9.06 p = 0.02 b1 = 0.01 ; b0 = -0.37 p = 0.94 validated critical power (watt)

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VT

IAT

Dmax

CP

OBLA

LT2

RCP

AT HRDP MLSS VT2 HHbDP

VAM

Correspondance between measures?

3-minSMtest

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VT

IAT

Dmax CP OBLA

LT2

RCP

AT HRDP MLSS VT2

HHbDP VAM

Same thing from different angles?

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  • O2 - exercise intensity in

Incremental vs Constant PO exercise The issue of “Translation”

Intensity (PO, speed) V O2 (L·min-1 or %) LT Critical Intensity V O2max GET/VT1 CP/MLSS

moderate heavy severe extreme moderate heavy severe

MRT

Ramp-incremental Constant-intensity

Pupper

Keir et al. (in review)

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25 50 75 100 125 150 175 200 225 250 275 300 325 350 375 400 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5

VO2p (L⋅min

  • 1)

WR (watts)

Power Output (watts)

Incremental exercise→ Constant PO

3.1 L·min-1 = 270 W

MRT

3.1 L·min-1 = 250 W

  • O2p (L·min-1)

correctedW= (VO2-intercept) – ∆W * MRT

∆time slope

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25 50 75 100 125 150 175 200 225 250 275 300 325 350 375 400 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5

VO2p (L⋅min

  • 1)

WR (watts)

VO2p (L·min-1)

Power Output (watts)

Incremental exercise → Constant PO

Slow Component

correctedW= - (VO2-VO2@GET) * (slope2-slope1)

(slope2 * slope1)

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CP, RCP, MLSS and HHBBP occur at equivalent VO2?

Keir DA, MSSE, 2015 N=12

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Keir DA, MSSE, 2015

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How to measure heavy- severe boundary

WE HAVE «SMART» ALTERNATIVES INTERCHANGEABLE «WITH CARE»

TO DETERMINE AND MONITOR THE LIMITS OF TOLERABLE ENDURANCE EXERCISE AND ALLOW INDIVIDUALISED TRAINING LOAD QUANTIFICATION

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Individual Measure of heavy-severe boundary «Translate» it correctly =

Essential for exercise quantification and development of evidence-based, individualised exercise prescription to improve exercise tolerance

AND THAT’S ALL I HAVE TO SAY ABOUT THAT

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Carlo Capelli Enrico Tam Luca Dal Sacco Paolo Bruseghini Federico Fontana Giorgia Spigolon

Alessandro Colosio

Don Paterson Juan Murias Daniel Keir

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GRAZIE THANK YOU MERCI GRACIAS